BICYCLE THERAPEUTICS PLC

BICYCLE THERAPEUTICS PLCBCYCEarnings & Financial Report

Nasdaq · Health Care · Pharmaceutical Preparations

Bicycle Therapeutics PLC is a clinical-stage biopharmaceutical firm developing innovative bicyclic peptide therapies for unmet medical needs. Its core pipeline covers oncology, rare diseases, and immunological disorders, with operations in Europe and North America, and partnerships with global pharma leaders to advance drug candidates to market.

BCYC Q4 FY2025 Key Financial Metrics

Revenue

$48.0M

Gross Profit

N/A

Operating Profit

$-24.7M

Net Profit

$-20.2M

Gross Margin

N/A

Operating Margin

-51.5%

Net Margin

-42.0%

YoY Growth

1193.3%

EPS

$-0.29

BICYCLE THERAPEUTICS PLC Q4 FY2025 Financial Summary

BICYCLE THERAPEUTICS PLC reported revenue of $48.0M (up 1193.3% YoY) for Q4 FY2025, with a net profit of $-20.2M (up 61.1% YoY) (-42.0% margin).

Key Financial Metrics

Total Revenue$48.0M
Net Profit$-20.2M
Gross MarginN/A
Operating Margin-51.5%
Report PeriodQ4 FY2025

BICYCLE THERAPEUTICS PLC Annual Revenue by Year

BICYCLE THERAPEUTICS PLC annual revenue history includes year-by-year totals (for example, 2025 revenue was $72.6M).

YearAnnual Revenue
2025$72.6Mvs 2024
2024$35.3Mvs 2023
2023$27.0Mvs 2022
2022$14.5M

BICYCLE THERAPEUTICS PLC Quarterly Revenue & Net Profit History

BICYCLE THERAPEUTICS PLC results over the last 8 reported quarters, including revenue, net profit and year-over-year growth.

QuarterRevenueRevenue YoYNet ProfitNet Margin
Q4 FY2025$48.0M+1193.3%$-20.2M-42.0%
Q3 FY2025$11.7M+338.5%$-59.1M-503.7%
Q2 FY2025$2.9M-68.8%$-79.0M-2703.8%
Q1 FY2025$10.0M-48.9%$-60.8M-608.9%
Q4 FY2024$3.7M-30.4%N/AN/A
Q3 FY2024$2.7M-50.0%$-50.8M-1898.4%
Q2 FY2024$9.4M-17.9%$-39.8M-425.3%
Q1 FY2024$19.5M+298.9%$-26.6M-136.0%

Income Statement

Q1 2024Q2 2024Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025
Revenue$19.5M$9.4M$2.7M$3.7M$10.0M$2.9M$11.7M$48.0M
YoY Growth298.9%-17.9%-50.0%-30.4%-48.9%-68.8%338.5%1193.3%

Balance Sheet

Q1 2024Q2 2024Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025
Assets$547.1M$1.06B$996.7M$956.9M$883.9M$832.2M$764.0M$717.6M
Liabilities$191.1M$183.5M$165.7M$163.8M$143.6M$163.3M$145.5M$107.6M
Equity$356.0M$873.8M$831.0M$793.1M$740.3M$668.9M$618.5M$610.0M

Cash Flow

Q1 2024Q2 2024Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025
Operating CF$-70.9M$-44.6M$-39.8M$-164.7M$-86.4M$-72.8M$-71.2M$-19.3M