vs

Side-by-side financial comparison of APPLIED OPTOELECTRONICS, INC. (AAOI) and REPLIGEN CORP (RGEN). Click either name above to swap in a different company.

REPLIGEN CORP is the larger business by last-quarter revenue ($197.9M vs $134.3M, roughly 1.5× APPLIED OPTOELECTRONICS, INC.). On growth, APPLIED OPTOELECTRONICS, INC. posted the faster year-over-year revenue change (33.9% vs 13.6%). REPLIGEN CORP produced more free cash flow last quarter ($17.6M vs $-104.6M). Over the past eight quarters, APPLIED OPTOELECTRONICS, INC.'s revenue compounded faster (81.7% CAGR vs 14.4%).

Applied Optoelectronics Inc. is an American semiconductor company that focuses on optical devices. It was founded in 1997 at the University of Houston and is headquartered in Sugar Land, Texas.

Repligen Corporation is a global life sciences company devoted to the development and commercialization of innovative bioprocessing technologies and systems that enable efficiencies in the process of manufacturing biological drugs.2025 The company is based in Waltham, Massachusetts,2014 and was incorporated in Delaware in 1981. A public company, Repligen is listed on the NASDAQ exchange under the symbol RGEN. As of 2025, Repligen employs over 1,900 employees globally and serves primarily biop...

AAOI vs RGEN — Head-to-Head

Bigger by revenue
RGEN
RGEN
1.5× larger
RGEN
$197.9M
$134.3M
AAOI
Growing faster (revenue YoY)
AAOI
AAOI
+20.3% gap
AAOI
33.9%
13.6%
RGEN
More free cash flow
RGEN
RGEN
$122.2M more FCF
RGEN
$17.6M
$-104.6M
AAOI
Faster 2-yr revenue CAGR
AAOI
AAOI
Annualised
AAOI
81.7%
14.4%
RGEN

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
AAOI
AAOI
RGEN
RGEN
Revenue
$134.3M
$197.9M
Net Profit
$13.3M
Gross Margin
31.2%
52.5%
Operating Margin
-8.6%
9.0%
Net Margin
6.7%
Revenue YoY
33.9%
13.6%
Net Profit YoY
143.9%
EPS (diluted)
$-0.02
$0.24

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
AAOI
AAOI
RGEN
RGEN
Q4 25
$134.3M
$197.9M
Q3 25
$118.6M
$188.8M
Q2 25
$103.0M
$182.4M
Q1 25
$99.9M
$169.2M
Q4 24
$100.3M
$174.1M
Q3 24
$65.2M
$154.9M
Q2 24
$43.3M
$154.1M
Q1 24
$40.7M
$151.3M
Net Profit
AAOI
AAOI
RGEN
RGEN
Q4 25
$13.3M
Q3 25
$-17.9M
$14.9M
Q2 25
$-9.1M
$14.9M
Q1 25
$-9.2M
$5.8M
Q4 24
$-30.3M
Q3 24
$-17.8M
$-654.0K
Q2 24
$-26.1M
$3.3M
Q1 24
$-23.2M
$2.1M
Gross Margin
AAOI
AAOI
RGEN
RGEN
Q4 25
31.2%
52.5%
Q3 25
28.0%
53.2%
Q2 25
30.3%
50.0%
Q1 25
30.6%
53.6%
Q4 24
28.7%
26.1%
Q3 24
24.4%
50.0%
Q2 24
22.1%
49.8%
Q1 24
18.7%
49.5%
Operating Margin
AAOI
AAOI
RGEN
RGEN
Q4 25
-8.6%
9.0%
Q3 25
-15.3%
8.9%
Q2 25
-15.5%
7.6%
Q1 25
-8.9%
3.9%
Q4 24
-6.5%
-17.7%
Q3 24
-25.4%
-5.1%
Q2 24
-60.7%
1.0%
Q1 24
-53.2%
1.3%
Net Margin
AAOI
AAOI
RGEN
RGEN
Q4 25
6.7%
Q3 25
-15.1%
7.9%
Q2 25
-8.8%
8.2%
Q1 25
-9.2%
3.4%
Q4 24
-17.4%
Q3 24
-27.3%
-0.4%
Q2 24
-60.4%
2.2%
Q1 24
-57.0%
1.4%
EPS (diluted)
AAOI
AAOI
RGEN
RGEN
Q4 25
$-0.02
$0.24
Q3 25
$-0.28
$0.26
Q2 25
$-0.16
$0.26
Q1 25
$-0.18
$0.10
Q4 24
$-2.82
$-0.55
Q3 24
$-0.42
$-0.01
Q2 24
$-0.66
$0.06
Q1 24
$-0.60
$0.04

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
AAOI
AAOI
RGEN
RGEN
Cash + ST InvestmentsLiquidity on hand
$206.1M
$767.6M
Total DebtLower is stronger
$34.0M
$542.2M
Stockholders' EquityBook value
$733.9M
$2.1B
Total Assets
$1.2B
$2.9B
Debt / EquityLower = less leverage
0.05×
0.26×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
AAOI
AAOI
RGEN
RGEN
Q4 25
$206.1M
$767.6M
Q3 25
$137.0M
$748.7M
Q2 25
$64.7M
$708.9M
Q1 25
$51.1M
$697.2M
Q4 24
$67.4M
$757.4M
Q3 24
$34.1M
$784.0M
Q2 24
$10.7M
$809.1M
Q1 24
$8.4M
$780.6M
Total Debt
AAOI
AAOI
RGEN
RGEN
Q4 25
$34.0M
$542.2M
Q3 25
$537.9M
Q2 25
Q1 25
$22.1M
Q4 24
$26.7M
$525.6M
Q3 24
$29.5M
Q2 24
$22.5M
Q1 24
$24.1M
Stockholders' Equity
AAOI
AAOI
RGEN
RGEN
Q4 25
$733.9M
$2.1B
Q3 25
$559.1M
$2.1B
Q2 25
$425.0M
$2.1B
Q1 25
$309.0M
$2.0B
Q4 24
$229.1M
$2.0B
Q3 24
$212.1M
$2.0B
Q2 24
$186.5M
$2.0B
Q1 24
$195.7M
$2.0B
Total Assets
AAOI
AAOI
RGEN
RGEN
Q4 25
$1.2B
$2.9B
Q3 25
$978.5M
$2.9B
Q2 25
$796.9M
$2.9B
Q1 25
$644.7M
$2.9B
Q4 24
$547.0M
$2.8B
Q3 24
$410.0M
$2.8B
Q2 24
$348.0M
$2.9B
Q1 24
$350.9M
$2.8B
Debt / Equity
AAOI
AAOI
RGEN
RGEN
Q4 25
0.05×
0.26×
Q3 25
0.26×
Q2 25
Q1 25
0.07×
Q4 24
0.12×
0.27×
Q3 24
0.14×
Q2 24
0.12×
Q1 24
0.12×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
AAOI
AAOI
RGEN
RGEN
Operating Cash FlowLast quarter
$-29.6M
$25.7M
Free Cash FlowOCF − Capex
$-104.6M
$17.6M
FCF MarginFCF / Revenue
-77.9%
8.9%
Capex IntensityCapex / Revenue
55.9%
4.1%
Cash ConversionOCF / Net Profit
1.93×
TTM Free Cash FlowTrailing 4 quarters
$-353.6M
$93.9M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
AAOI
AAOI
RGEN
RGEN
Q4 25
$-29.6M
$25.7M
Q3 25
$-28.5M
$48.1M
Q2 25
$-65.5M
$28.6M
Q1 25
$-50.9M
$15.0M
Q4 24
$-24.6M
$39.2M
Q3 24
$-14.4M
$49.3M
Q2 24
$-2.0M
$42.2M
Q1 24
$-28.5M
$44.7M
Free Cash Flow
AAOI
AAOI
RGEN
RGEN
Q4 25
$-104.6M
$17.6M
Q3 25
$-78.7M
$43.4M
Q2 25
$-91.0M
$21.5M
Q1 25
$-79.3M
$11.4M
Q4 24
$-53.0M
$33.6M
Q3 24
$-20.7M
$42.3M
Q2 24
$-5.0M
$37.4M
Q1 24
$-34.2M
$36.4M
FCF Margin
AAOI
AAOI
RGEN
RGEN
Q4 25
-77.9%
8.9%
Q3 25
-66.3%
23.0%
Q2 25
-88.3%
11.8%
Q1 25
-79.4%
6.8%
Q4 24
-52.9%
19.3%
Q3 24
-31.8%
27.3%
Q2 24
-11.5%
24.3%
Q1 24
-84.2%
24.0%
Capex Intensity
AAOI
AAOI
RGEN
RGEN
Q4 25
55.9%
4.1%
Q3 25
42.4%
2.5%
Q2 25
24.7%
3.9%
Q1 25
28.4%
2.1%
Q4 24
28.3%
3.2%
Q3 24
9.7%
4.5%
Q2 24
6.9%
3.1%
Q1 24
14.2%
5.5%
Cash Conversion
AAOI
AAOI
RGEN
RGEN
Q4 25
1.93×
Q3 25
3.23×
Q2 25
1.92×
Q1 25
2.57×
Q4 24
Q3 24
Q2 24
12.70×
Q1 24
21.35×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

AAOI
AAOI

Data Center$74.9M56%
CATV$54.0M40%
Telecom$5.1M4%

RGEN
RGEN

Segment breakdown not available.

Related Comparisons