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Side-by-side financial comparison of ADVANCE AUTO PARTS INC (AAP) and Vertex Pharmaceuticals (VRTX). Click either name above to swap in a different company.

Vertex Pharmaceuticals is the larger business by last-quarter revenue ($3.2B vs $2.0B, roughly 1.6× ADVANCE AUTO PARTS INC). Vertex Pharmaceuticals runs the higher net margin — 37.3% vs 0.3%, a 37.0% gap on every dollar of revenue. On growth, ADVANCE AUTO PARTS INC posted the faster year-over-year revenue change (130.1% vs 9.5%). Vertex Pharmaceuticals produced more free cash flow last quarter ($348.6M vs $-21.0M). Over the past eight quarters, Vertex Pharmaceuticals's revenue compounded faster (8.9% CAGR vs -15.7%).

Advance Auto Parts, Inc. is an American automotive aftermarket parts provider. Headquartered in Raleigh, North Carolina, it serves professional installer and do it yourself (DIY) customers.

Vertex Pharmaceuticals Incorporated is an American biopharmaceutical company based in Boston, Massachusetts. It was one of the first biotech firms to use an explicit strategy of rational drug design rather than combinatorial chemistry. It maintains headquarters in Boston, Massachusetts, and three research facilities, in San Diego, California, and Milton Park, Oxfordshire, England.

AAP vs VRTX — Head-to-Head

Bigger by revenue
VRTX
VRTX
1.6× larger
VRTX
$3.2B
$2.0B
AAP
Growing faster (revenue YoY)
AAP
AAP
+120.6% gap
AAP
130.1%
9.5%
VRTX
Higher net margin
VRTX
VRTX
37.0% more per $
VRTX
37.3%
0.3%
AAP
More free cash flow
VRTX
VRTX
$369.6M more FCF
VRTX
$348.6M
$-21.0M
AAP
Faster 2-yr revenue CAGR
VRTX
VRTX
Annualised
VRTX
8.9%
-15.7%
AAP

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
AAP
AAP
VRTX
VRTX
Revenue
$2.0B
$3.2B
Net Profit
$6.0M
$1.2B
Gross Margin
44.1%
85.4%
Operating Margin
2.2%
37.8%
Net Margin
0.3%
37.3%
Revenue YoY
130.1%
9.5%
Net Profit YoY
101.4%
30.5%
EPS (diluted)
$0.10
$4.64

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
AAP
AAP
VRTX
VRTX
Q1 26
$2.0B
Q4 25
$2.0B
$3.2B
Q3 25
$2.0B
$3.1B
Q2 25
$2.6B
$3.0B
Q1 25
$2.8B
Q4 24
$2.1B
$2.9B
Q3 24
$2.2B
$2.8B
Q2 24
$2.8B
$2.6B
Net Profit
AAP
AAP
VRTX
VRTX
Q1 26
$6.0M
Q4 25
$-1.0M
$1.2B
Q3 25
$15.0M
$1.1B
Q2 25
$24.0M
$1.0B
Q1 25
$646.3M
Q4 24
$-6.0M
$913.0M
Q3 24
$45.0M
$1.0B
Q2 24
$40.0M
$-3.6B
Gross Margin
AAP
AAP
VRTX
VRTX
Q1 26
44.1%
Q4 25
43.3%
85.4%
Q3 25
43.5%
86.5%
Q2 25
42.9%
86.3%
Q1 25
86.9%
Q4 24
42.3%
85.5%
Q3 24
43.6%
85.8%
Q2 24
43.4%
85.9%
Operating Margin
AAP
AAP
VRTX
VRTX
Q1 26
2.2%
Q4 25
1.1%
37.8%
Q3 25
1.1%
38.6%
Q2 25
-5.1%
38.8%
Q1 25
22.7%
Q4 24
35.2%
Q3 24
2.5%
40.3%
Q2 24
1.9%
-132.9%
Net Margin
AAP
AAP
VRTX
VRTX
Q1 26
0.3%
Q4 25
-0.0%
37.3%
Q3 25
0.7%
35.2%
Q2 25
0.9%
34.8%
Q1 25
23.3%
Q4 24
-0.3%
31.4%
Q3 24
2.1%
37.7%
Q2 24
1.4%
-135.8%
EPS (diluted)
AAP
AAP
VRTX
VRTX
Q1 26
$0.10
Q4 25
$-0.02
$4.64
Q3 25
$0.25
$4.20
Q2 25
$0.40
$3.99
Q1 25
$2.49
Q4 24
$-0.10
$3.62
Q3 24
$0.75
$4.01
Q2 24
$0.67
$-13.92

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
AAP
AAP
VRTX
VRTX
Cash + ST InvestmentsLiquidity on hand
$3.1B
$6.6B
Total DebtLower is stronger
$3.4B
Stockholders' EquityBook value
$2.2B
$18.7B
Total Assets
$11.8B
$25.6B
Debt / EquityLower = less leverage
1.55×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
AAP
AAP
VRTX
VRTX
Q1 26
$3.1B
Q4 25
$3.2B
$6.6B
Q3 25
$1.7B
$6.3B
Q2 25
$1.7B
$6.4B
Q1 25
$6.2B
Q4 24
$464.5M
$6.1B
Q3 24
$479.4M
$6.5B
Q2 24
$451.0M
$5.8B
Total Debt
AAP
AAP
VRTX
VRTX
Q1 26
$3.4B
Q4 25
$3.4B
Q3 25
$1.8B
Q2 25
$1.8B
Q1 25
Q4 24
$1.8B
Q3 24
$1.8B
Q2 24
$1.8B
Stockholders' Equity
AAP
AAP
VRTX
VRTX
Q1 26
$2.2B
Q4 25
$2.2B
$18.7B
Q3 25
$2.2B
$17.3B
Q2 25
$2.2B
$17.2B
Q1 25
$16.5B
Q4 24
$2.6B
$16.4B
Q3 24
$2.6B
$15.6B
Q2 24
$2.6B
$14.8B
Total Assets
AAP
AAP
VRTX
VRTX
Q1 26
$11.8B
Q4 25
$12.1B
$25.6B
Q3 25
$10.5B
$24.9B
Q2 25
$10.6B
$24.0B
Q1 25
$22.9B
Q4 24
$12.5B
$22.5B
Q3 24
$12.3B
$22.2B
Q2 24
$12.2B
$20.1B
Debt / Equity
AAP
AAP
VRTX
VRTX
Q1 26
1.55×
Q4 25
1.55×
Q3 25
0.81×
Q2 25
0.81×
Q1 25
Q4 24
0.69×
Q3 24
0.69×
Q2 24
0.70×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
AAP
AAP
VRTX
VRTX
Operating Cash FlowLast quarter
$72.0M
$498.0M
Free Cash FlowOCF − Capex
$-21.0M
$348.6M
FCF MarginFCF / Revenue
-1.1%
10.9%
Capex IntensityCapex / Revenue
4.7%
4.7%
Cash ConversionOCF / Net Profit
12.00×
0.42×
TTM Free Cash FlowTrailing 4 quarters
$-298.0M
$3.2B

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
AAP
AAP
VRTX
VRTX
Q1 26
$72.0M
Q4 25
$-12.0M
$498.0M
Q3 25
$50.0M
$1.2B
Q2 25
$-156.0M
$1.1B
Q1 25
$818.9M
Q4 24
$70.0M
$584.6M
Q3 24
$85.0M
$1.4B
Q2 24
$3.0M
$-3.8B
Free Cash Flow
AAP
AAP
VRTX
VRTX
Q1 26
$-21.0M
Q4 25
$-76.0M
$348.6M
Q3 25
$-3.0M
$1.1B
Q2 25
$-198.0M
$927.4M
Q1 25
$778.2M
Q4 24
$27.0M
$492.0M
Q3 24
$44.0M
$1.3B
Q2 24
$-43.0M
$-3.8B
FCF Margin
AAP
AAP
VRTX
VRTX
Q1 26
-1.1%
Q4 25
-3.7%
10.9%
Q3 25
-0.1%
37.0%
Q2 25
-7.7%
31.3%
Q1 25
28.1%
Q4 24
1.3%
16.9%
Q3 24
2.0%
47.0%
Q2 24
-1.6%
-144.5%
Capex Intensity
AAP
AAP
VRTX
VRTX
Q1 26
4.7%
Q4 25
3.1%
4.7%
Q3 25
2.6%
3.3%
Q2 25
1.6%
4.9%
Q1 25
1.5%
Q4 24
2.0%
3.2%
Q3 24
1.9%
2.4%
Q2 24
1.7%
2.6%
Cash Conversion
AAP
AAP
VRTX
VRTX
Q1 26
12.00×
Q4 25
0.42×
Q3 25
3.33×
1.15×
Q2 25
-6.50×
1.04×
Q1 25
1.27×
Q4 24
0.64×
Q3 24
1.89×
1.31×
Q2 24
0.07×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

AAP
AAP

Segment breakdown not available.

VRTX
VRTX

TRIKAFTAKAFTRIO$2.6B81%
ALYFTREK$380.1M12%
Manufactured Product Other$237.4M7%

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