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Side-by-side financial comparison of ASCENTAGE PHARMA GROUP INTERNATIONAL (AAPG) and Aclaris Therapeutics, Inc. (ACRS). Click either name above to swap in a different company.

Aclaris Therapeutics, Inc. is the larger business by last-quarter revenue ($1.3M vs $574.1K, roughly 2.3× ASCENTAGE PHARMA GROUP INTERNATIONAL).

Ascentage Pharma Group International is a global clinical-stage biotechnology company specializing in developing novel targeted therapies for cancers, chronic viral infections, and age-related diseases. It focuses on small molecule drugs targeting apoptosis pathways and other key oncogenic mechanisms, with operations spanning China, the U.S., and other global markets, serving patients with unmet medical needs worldwide.

Aclaris Therapeutics, Inc. is a clinical-stage biopharmaceutical firm focused on developing targeted therapies for immunological, inflammatory, and dermatological diseases. Its pipeline includes candidates for unmet needs like alopecia areata and vitiligo, serving global patient groups.

AAPG vs ACRS — Head-to-Head

Bigger by revenue
ACRS
ACRS
2.3× larger
ACRS
$1.3M
$574.1K
AAPG

Income Statement — Q4 2025 vs Q4 2025

Metric
AAPG
AAPG
ACRS
ACRS
Revenue
$574.1K
$1.3M
Net Profit
$-19.8M
Gross Margin
58.9%
Operating Margin
-1755.5%
Net Margin
-1528.6%
Revenue YoY
-85.9%
Net Profit YoY
79.5%
EPS (diluted)
$-0.16

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
AAPG
AAPG
ACRS
ACRS
Q4 25
$574.1K
$1.3M
Q3 25
$3.3M
Q2 25
$32.6M
$1.8M
Q1 25
$1.5M
Q4 24
$9.2M
Q3 24
$4.3M
Q2 24
$2.8M
Q1 24
$2.4M
Net Profit
AAPG
AAPG
ACRS
ACRS
Q4 25
$-19.8M
Q3 25
$-14.6M
Q2 25
$11.4M
$-15.4M
Q1 25
$-15.1M
Q4 24
$-96.6M
Q3 24
$-7.6M
Q2 24
$-11.0M
Q1 24
$-16.9M
Gross Margin
AAPG
AAPG
ACRS
ACRS
Q4 25
58.9%
Q3 25
83.7%
Q2 25
90.7%
71.0%
Q1 25
65.2%
Q4 24
92.3%
Q3 24
85.0%
Q2 24
77.4%
Q1 24
66.3%
Operating Margin
AAPG
AAPG
ACRS
ACRS
Q4 25
-1755.5%
Q3 25
-519.8%
Q2 25
-1035.9%
Q1 25
-1242.9%
Q4 24
-1082.3%
Q3 24
-240.9%
Q2 24
-464.7%
Q1 24
-789.4%
Net Margin
AAPG
AAPG
ACRS
ACRS
Q4 25
-1528.6%
Q3 25
-443.0%
Q2 25
-868.3%
Q1 25
-1036.8%
Q4 24
-1048.3%
Q3 24
-174.6%
Q2 24
-397.2%
Q1 24
-706.5%
EPS (diluted)
AAPG
AAPG
ACRS
ACRS
Q4 25
$-0.16
Q3 25
$-0.12
Q2 25
$-0.13
Q1 25
$-0.12
Q4 24
$-1.21
Q3 24
$-0.11
Q2 24
$-0.15
Q1 24
$-0.24

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
AAPG
AAPG
ACRS
ACRS
Cash + ST InvestmentsLiquidity on hand
$20.0M
Total DebtLower is stronger
Stockholders' EquityBook value
$103.1M
Total Assets
$160.5M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
AAPG
AAPG
ACRS
ACRS
Q4 25
$20.0M
Q3 25
$25.3M
Q2 25
$25.4M
Q1 25
$30.4M
Q4 24
$24.6M
Q3 24
$47.7M
Q2 24
$22.8M
Q1 24
$35.8M
Stockholders' Equity
AAPG
AAPG
ACRS
ACRS
Q4 25
$103.1M
Q3 25
$120.1M
Q2 25
$131.7M
Q1 25
$144.1M
Q4 24
$155.6M
Q3 24
$130.2M
Q2 24
$133.8M
Q1 24
$142.0M
Total Assets
AAPG
AAPG
ACRS
ACRS
Q4 25
$160.5M
Q3 25
$175.5M
Q2 25
$189.1M
Q1 25
$198.1M
Q4 24
$220.3M
Q3 24
$182.4M
Q2 24
$161.1M
Q1 24
$174.1M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
AAPG
AAPG
ACRS
ACRS
Operating Cash FlowLast quarter
$-13.1M
Free Cash FlowOCF − Capex
$-13.2M
FCF MarginFCF / Revenue
-1015.8%
Capex IntensityCapex / Revenue
1.9%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-47.2M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
AAPG
AAPG
ACRS
ACRS
Q4 25
$-13.1M
Q3 25
$-10.9M
Q2 25
$-10.0M
Q1 25
$-13.1M
Q4 24
$-8.9M
Q3 24
$22.0M
Q2 24
$-12.3M
Q1 24
$-20.8M
Free Cash Flow
AAPG
AAPG
ACRS
ACRS
Q4 25
$-13.2M
Q3 25
$-11.0M
Q2 25
$-10.0M
Q1 25
$-13.1M
Q4 24
Q3 24
Q2 24
$-12.3M
Q1 24
$-20.9M
FCF Margin
AAPG
AAPG
ACRS
ACRS
Q4 25
-1015.8%
Q3 25
-332.1%
Q2 25
-563.5%
Q1 25
-900.3%
Q4 24
Q3 24
Q2 24
-446.0%
Q1 24
-873.6%
Capex Intensity
AAPG
AAPG
ACRS
ACRS
Q4 25
1.9%
Q3 25
0.7%
Q2 25
1.2%
Q1 25
3.0%
Q4 24
0.0%
Q3 24
0.0%
Q2 24
0.5%
Q1 24
5.6%

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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