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Side-by-side financial comparison of ACADIA PHARMACEUTICALS INC (ACAD) and IDEAYA Biosciences, Inc. (IDYA). Click either name above to swap in a different company.

ACADIA PHARMACEUTICALS INC is the larger business by last-quarter revenue ($284.0M vs $207.8M, roughly 1.4× IDEAYA Biosciences, Inc.). ACADIA PHARMACEUTICALS INC runs the higher net margin — 96.3% vs 57.4%, a 39.0% gap on every dollar of revenue.

Acadia Pharmaceuticals Inc. is a biopharmaceutical company headquartered in Del Mar, San Diego, California.

IDEAYA Biosciences, Inc. is a clinical-stage biotechnology company focused on oncology, developing targeted therapies and synthetic lethality treatments for patients with genetically defined cancers. It advances a pipeline of candidates across multiple tumor types, partnering with industry stakeholders to accelerate global access to innovative cancer care solutions.

ACAD vs IDYA — Head-to-Head

Bigger by revenue
ACAD
ACAD
1.4× larger
ACAD
$284.0M
$207.8M
IDYA
Higher net margin
ACAD
ACAD
39.0% more per $
ACAD
96.3%
57.4%
IDYA

Income Statement — Q4 FY2025 vs Q3 FY2025

Metric
ACAD
ACAD
IDYA
IDYA
Revenue
$284.0M
$207.8M
Net Profit
$273.6M
$119.2M
Gross Margin
90.8%
Operating Margin
6.1%
52.2%
Net Margin
96.3%
57.4%
Revenue YoY
9.4%
Net Profit YoY
90.3%
330.1%
EPS (diluted)
$1.61
$1.33

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ACAD
ACAD
IDYA
IDYA
Q4 25
$284.0M
Q3 25
$278.6M
$207.8M
Q2 25
$264.6M
Q1 25
$244.3M
Q4 24
$259.6M
Q3 24
$250.4M
$0
Q2 24
$242.0M
$0
Q1 24
$205.8M
$0
Net Profit
ACAD
ACAD
IDYA
IDYA
Q4 25
$273.6M
Q3 25
$71.8M
$119.2M
Q2 25
$26.7M
Q1 25
$19.0M
Q4 24
$143.7M
Q3 24
$32.8M
$-51.8M
Q2 24
$33.4M
$-52.8M
Q1 24
$16.6M
$-39.6M
Gross Margin
ACAD
ACAD
IDYA
IDYA
Q4 25
90.8%
Q3 25
92.2%
Q2 25
92.2%
Q1 25
91.7%
Q4 24
91.6%
Q3 24
92.5%
Q2 24
92.5%
Q1 24
88.8%
Operating Margin
ACAD
ACAD
IDYA
IDYA
Q4 25
6.1%
Q3 25
12.8%
52.2%
Q2 25
12.2%
Q1 25
7.9%
Q4 24
59.1%
Q3 24
12.6%
Q2 24
12.6%
Q1 24
7.4%
Net Margin
ACAD
ACAD
IDYA
IDYA
Q4 25
96.3%
Q3 25
25.8%
57.4%
Q2 25
10.1%
Q1 25
7.8%
Q4 24
55.4%
Q3 24
13.1%
Q2 24
13.8%
Q1 24
8.0%
EPS (diluted)
ACAD
ACAD
IDYA
IDYA
Q4 25
$1.61
Q3 25
$0.42
$1.33
Q2 25
$0.16
Q1 25
$0.11
Q4 24
$0.86
Q3 24
$0.20
$-0.60
Q2 24
$0.20
$-0.68
Q1 24
$0.10
$-0.53

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ACAD
ACAD
IDYA
IDYA
Cash + ST InvestmentsLiquidity on hand
$177.7M
$786.9M
Total DebtLower is stronger
Stockholders' EquityBook value
$1.2B
$1.1B
Total Assets
$1.6B
$1.2B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ACAD
ACAD
IDYA
IDYA
Q4 25
$177.7M
Q3 25
$258.0M
$786.9M
Q2 25
$253.6M
Q1 25
$217.7M
Q4 24
$319.6M
Q3 24
$155.1M
$920.0M
Q2 24
$177.1M
$701.7M
Q1 24
$204.7M
$698.8M
Stockholders' Equity
ACAD
ACAD
IDYA
IDYA
Q4 25
$1.2B
Q3 25
$917.3M
$1.1B
Q2 25
$822.4M
Q1 25
$765.2M
Q4 24
$732.8M
Q3 24
$577.2M
$1.2B
Q2 24
$516.7M
$931.7M
Q1 24
$464.0M
$935.3M
Total Assets
ACAD
ACAD
IDYA
IDYA
Q4 25
$1.6B
Q3 25
$1.3B
$1.2B
Q2 25
$1.2B
Q1 25
$1.1B
Q4 24
$1.2B
Q3 24
$976.9M
$1.2B
Q2 24
$914.1M
$973.7M
Q1 24
$855.1M
$961.5M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ACAD
ACAD
IDYA
IDYA
Operating Cash FlowLast quarter
$-48.7M
$142.2M
Free Cash FlowOCF − Capex
$142.2M
FCF MarginFCF / Revenue
68.4%
Capex IntensityCapex / Revenue
0.0%
Cash ConversionOCF / Net Profit
-0.18×
1.19×
TTM Free Cash FlowTrailing 4 quarters
$13.5M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ACAD
ACAD
IDYA
IDYA
Q4 25
$-48.7M
Q3 25
$74.3M
$142.2M
Q2 25
$64.0M
Q1 25
$20.3M
Q4 24
$40.4M
Q3 24
$63.2M
$-49.2M
Q2 24
$25.0M
$-32.9M
Q1 24
$29.1M
$-43.8M
Free Cash Flow
ACAD
ACAD
IDYA
IDYA
Q4 25
Q3 25
$73.9M
$142.2M
Q2 25
Q1 25
Q4 24
Q3 24
$63.2M
$-49.7M
Q2 24
$-33.9M
Q1 24
$-45.1M
FCF Margin
ACAD
ACAD
IDYA
IDYA
Q4 25
Q3 25
26.5%
68.4%
Q2 25
Q1 25
Q4 24
Q3 24
25.2%
Q2 24
Q1 24
Capex Intensity
ACAD
ACAD
IDYA
IDYA
Q4 25
Q3 25
0.1%
0.0%
Q2 25
Q1 25
Q4 24
Q3 24
0.0%
Q2 24
Q1 24
Cash Conversion
ACAD
ACAD
IDYA
IDYA
Q4 25
-0.18×
Q3 25
1.03×
1.19×
Q2 25
2.40×
Q1 25
1.07×
Q4 24
0.28×
Q3 24
1.93×
Q2 24
0.75×
Q1 24
1.76×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

ACAD
ACAD

Nuplazid$174.4M61%
Daybue$109.6M39%

IDYA
IDYA

Segment breakdown not available.

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