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Side-by-side financial comparison of ProFrac Holding Corp. (ACDC) and Ascendis Pharma A/S (ASND). Click either name above to swap in a different company.

ProFrac Holding Corp. is the larger business by last-quarter revenue ($436.5M vs $267.3M, roughly 1.6× Ascendis Pharma A/S). On growth, Ascendis Pharma A/S posted the faster year-over-year revenue change (42.3% vs -4.0%). Over the past eight quarters, Ascendis Pharma A/S's revenue compounded faster (60.7% CAGR vs -13.4%).

ProFrac Holding Corp. is a leading North American energy services firm that provides hydraulic fracturing, well completion, and associated support services to upstream oil and gas exploration and production operators. It primarily serves clients active across major onshore shale and conventional hydrocarbon production basins in the U.S. and Canada.

Growth hormone therapy refers to the use of growth hormone (GH) as a prescription medication—it is one form of hormone therapy. Growth hormone is a peptide hormone secreted by the pituitary gland that stimulates growth and cell reproduction. In the past, growth hormone was extracted from human pituitary glands. Growth hormone is now produced by recombinant DNA technology and is prescribed for a variety of reasons. GH therapy has been a focus of social and ethical controversies for 50 years.

ACDC vs ASND — Head-to-Head

Bigger by revenue
ACDC
ACDC
1.6× larger
ACDC
$436.5M
$267.3M
ASND
Growing faster (revenue YoY)
ASND
ASND
+46.3% gap
ASND
42.3%
-4.0%
ACDC
Faster 2-yr revenue CAGR
ASND
ASND
Annualised
ASND
60.7%
-13.4%
ACDC

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
ACDC
ACDC
ASND
ASND
Revenue
$436.5M
$267.3M
Net Profit
$-144.7M
Gross Margin
90.5%
Operating Margin
-24.9%
Net Margin
-33.2%
Revenue YoY
-4.0%
42.3%
Net Profit YoY
-37.8%
EPS (diluted)
$-0.83

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ACDC
ACDC
ASND
ASND
Q4 25
$436.5M
$267.3M
Q3 25
$403.1M
$230.7M
Q2 25
$501.9M
$170.7M
Q1 25
$600.3M
$109.0M
Q4 24
$454.7M
$187.8M
Q3 24
$575.3M
$62.5M
Q2 24
$579.4M
$38.9M
Q1 24
$581.5M
$103.6M
Net Profit
ACDC
ACDC
ASND
ASND
Q4 25
$-144.7M
Q3 25
$-100.9M
$-65.9M
Q2 25
$-105.9M
$-42.0M
Q1 25
$-17.5M
$-102.2M
Q4 24
$-105.0M
Q3 24
$-45.2M
$-107.1M
Q2 24
$-66.7M
$-118.1M
Q1 24
$1.8M
$-141.5M
Gross Margin
ACDC
ACDC
ASND
ASND
Q4 25
90.5%
Q3 25
89.5%
Q2 25
80.1%
Q1 25
82.6%
Q4 24
91.9%
Q3 24
80.6%
Q2 24
68.2%
Q1 24
92.1%
Operating Margin
ACDC
ACDC
ASND
ASND
Q4 25
-24.9%
Q3 25
-19.5%
5.1%
Q2 25
-10.8%
-33.5%
Q1 25
2.7%
-103.2%
Q4 24
-10.3%
Q3 24
-0.7%
-167.3%
Q2 24
-8.5%
-370.2%
Q1 24
6.9%
-51.2%
Net Margin
ACDC
ACDC
ASND
ASND
Q4 25
-33.2%
Q3 25
-25.0%
-28.5%
Q2 25
-21.1%
-24.6%
Q1 25
-2.9%
-93.7%
Q4 24
-23.1%
Q3 24
-7.9%
-171.5%
Q2 24
-11.5%
-303.9%
Q1 24
0.3%
-136.6%
EPS (diluted)
ACDC
ACDC
ASND
ASND
Q4 25
$-0.83
Q3 25
$-0.60
Q2 25
$-0.67
Q1 25
$-0.12
Q4 24
$-0.67
Q3 24
$-0.29
Q2 24
$-0.42
Q1 24
$0.00

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ACDC
ACDC
ASND
ASND
Cash + ST InvestmentsLiquidity on hand
$22.9M
$665.3M
Total DebtLower is stronger
$832.7M
Stockholders' EquityBook value
$717.5M
$-175.8M
Total Assets
$2.6B
$1.4B
Debt / EquityLower = less leverage
1.16×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ACDC
ACDC
ASND
ASND
Q4 25
$22.9M
$665.3M
Q3 25
$58.0M
$582.2M
Q2 25
$26.0M
$533.6M
Q1 25
$16.0M
$559.4M
Q4 24
$14.8M
$604.3M
Q3 24
$25.5M
$675.6M
Q2 24
$24.0M
$279.4M
Q1 24
$28.3M
$345.9M
Total Debt
ACDC
ACDC
ASND
ASND
Q4 25
$832.7M
Q3 25
$907.0M
Q2 25
$941.9M
Q1 25
$967.9M
Q4 24
$936.1M
Q3 24
$986.7M
Q2 24
$1.0B
Q1 24
$895.1M
Stockholders' Equity
ACDC
ACDC
ASND
ASND
Q4 25
$717.5M
$-175.8M
Q3 25
$862.0M
$-188.0M
Q2 25
$875.5M
$-202.6M
Q1 25
$988.1M
$-205.0M
Q4 24
$1.0B
$-114.2M
Q3 24
$1.1B
$-105.1M
Q2 24
$1.1B
$-346.8M
Q1 24
$1.2B
$-257.2M
Total Assets
ACDC
ACDC
ASND
ASND
Q4 25
$2.6B
$1.4B
Q3 25
$2.7B
$1.2B
Q2 25
$2.8B
$1.2B
Q1 25
$3.0B
$1.1B
Q4 24
$3.0B
$1.3B
Q3 24
$3.1B
$1.2B
Q2 24
$3.2B
$819.0M
Q1 24
$3.0B
$866.7M
Debt / Equity
ACDC
ACDC
ASND
ASND
Q4 25
1.16×
Q3 25
1.05×
Q2 25
1.08×
Q1 25
0.98×
Q4 24
0.93×
Q3 24
0.90×
Q2 24
0.88×
Q1 24
0.74×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ACDC
ACDC
ASND
ASND
Operating Cash FlowLast quarter
$49.5M
$58.2M
Free Cash FlowOCF − Capex
$12.9M
FCF MarginFCF / Revenue
3.0%
Capex IntensityCapex / Revenue
8.4%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$19.6M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ACDC
ACDC
ASND
ASND
Q4 25
$49.5M
$58.2M
Q3 25
$900.0K
Q2 25
$100.4M
Q1 25
$38.7M
$-15.5M
Q4 24
$76.5M
$-330.7M
Q3 24
$98.2M
Q2 24
$113.5M
Q1 24
$79.1M
$-109.7M
Free Cash Flow
ACDC
ACDC
ASND
ASND
Q4 25
$12.9M
Q3 25
$-33.4M
Q2 25
$53.9M
Q1 25
$-13.8M
Q4 24
$13.3M
Q3 24
$28.2M
Q2 24
$51.6M
Q1 24
$19.2M
FCF Margin
ACDC
ACDC
ASND
ASND
Q4 25
3.0%
Q3 25
-8.3%
Q2 25
10.7%
Q1 25
-2.3%
Q4 24
2.9%
Q3 24
4.9%
Q2 24
8.9%
Q1 24
3.3%
Capex Intensity
ACDC
ACDC
ASND
ASND
Q4 25
8.4%
Q3 25
8.5%
Q2 25
9.3%
Q1 25
8.7%
Q4 24
13.9%
Q3 24
12.2%
Q2 24
10.7%
Q1 24
10.3%
Cash Conversion
ACDC
ACDC
ASND
ASND
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
43.94×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

ACDC
ACDC

Services$385.6M88%
Products$50.9M12%

ASND
ASND

Segment breakdown not available.

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