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Side-by-side financial comparison of AXCELIS TECHNOLOGIES INC (ACLS) and Ascendis Pharma A/S (ASND). Click either name above to swap in a different company.

Ascendis Pharma A/S is the larger business by last-quarter revenue ($267.3M vs $238.3M, roughly 1.1× AXCELIS TECHNOLOGIES INC). On growth, Ascendis Pharma A/S posted the faster year-over-year revenue change (42.3% vs -5.6%). Over the past eight quarters, Ascendis Pharma A/S's revenue compounded faster (60.7% CAGR vs -2.8%).

Axcelis Technologies, Inc. is an American company engaging in the design, manufacture, and servicing of capital equipment for the semiconductor manufacturing industry worldwide. It produces ion implantation systems, including high and medium current implanters, and high energy implanters, and curing systems used in the fabrication of semiconductor chips. The company was incorporated in 1995 and is headquartered in Beverly, Massachusetts, United States.

Growth hormone therapy refers to the use of growth hormone (GH) as a prescription medication—it is one form of hormone therapy. Growth hormone is a peptide hormone secreted by the pituitary gland that stimulates growth and cell reproduction. In the past, growth hormone was extracted from human pituitary glands. Growth hormone is now produced by recombinant DNA technology and is prescribed for a variety of reasons. GH therapy has been a focus of social and ethical controversies for 50 years.

ACLS vs ASND — Head-to-Head

Bigger by revenue
ASND
ASND
1.1× larger
ASND
$267.3M
$238.3M
ACLS
Growing faster (revenue YoY)
ASND
ASND
+47.9% gap
ASND
42.3%
-5.6%
ACLS
Faster 2-yr revenue CAGR
ASND
ASND
Annualised
ASND
60.7%
-2.8%
ACLS

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
ACLS
ACLS
ASND
ASND
Revenue
$238.3M
$267.3M
Net Profit
$34.3M
Gross Margin
47.0%
90.5%
Operating Margin
15.2%
Net Margin
14.4%
Revenue YoY
-5.6%
42.3%
Net Profit YoY
-31.3%
EPS (diluted)
$1.11

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ACLS
ACLS
ASND
ASND
Q4 25
$238.3M
$267.3M
Q3 25
$213.6M
$230.7M
Q2 25
$194.5M
$170.7M
Q1 25
$192.6M
$109.0M
Q4 24
$252.4M
$187.8M
Q3 24
$256.6M
$62.5M
Q2 24
$256.5M
$38.9M
Q1 24
$252.4M
$103.6M
Net Profit
ACLS
ACLS
ASND
ASND
Q4 25
$34.3M
Q3 25
$26.0M
$-65.9M
Q2 25
$31.4M
$-42.0M
Q1 25
$28.6M
$-102.2M
Q4 24
$50.0M
Q3 24
$48.6M
$-107.1M
Q2 24
$50.9M
$-118.1M
Q1 24
$51.6M
$-141.5M
Gross Margin
ACLS
ACLS
ASND
ASND
Q4 25
47.0%
90.5%
Q3 25
41.6%
89.5%
Q2 25
44.9%
80.1%
Q1 25
46.1%
82.6%
Q4 24
46.0%
91.9%
Q3 24
42.9%
80.6%
Q2 24
43.8%
68.2%
Q1 24
46.0%
92.1%
Operating Margin
ACLS
ACLS
ASND
ASND
Q4 25
15.2%
Q3 25
11.7%
5.1%
Q2 25
14.9%
-33.5%
Q1 25
15.1%
-103.2%
Q4 24
21.6%
Q3 24
18.3%
-167.3%
Q2 24
20.6%
-370.2%
Q1 24
22.4%
-51.2%
Net Margin
ACLS
ACLS
ASND
ASND
Q4 25
14.4%
Q3 25
12.2%
-28.5%
Q2 25
16.1%
-24.6%
Q1 25
14.8%
-93.7%
Q4 24
19.8%
Q3 24
18.9%
-171.5%
Q2 24
19.8%
-303.9%
Q1 24
20.4%
-136.6%
EPS (diluted)
ACLS
ACLS
ASND
ASND
Q4 25
$1.11
Q3 25
$0.83
Q2 25
$0.98
Q1 25
$0.88
Q4 24
$1.54
Q3 24
$1.49
Q2 24
$1.55
Q1 24
$1.57

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ACLS
ACLS
ASND
ASND
Cash + ST InvestmentsLiquidity on hand
$374.3M
$665.3M
Total DebtLower is stronger
Stockholders' EquityBook value
$1.0B
$-175.8M
Total Assets
$1.4B
$1.4B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ACLS
ACLS
ASND
ASND
Q4 25
$374.3M
$665.3M
Q3 25
$449.6M
$582.2M
Q2 25
$549.8M
$533.6M
Q1 25
$587.1M
$559.4M
Q4 24
$571.3M
$604.3M
Q3 24
$579.4M
$675.6M
Q2 24
$548.3M
$279.4M
Q1 24
$530.2M
$345.9M
Stockholders' Equity
ACLS
ACLS
ASND
ASND
Q4 25
$1.0B
$-175.8M
Q3 25
$1.0B
$-188.0M
Q2 25
$1.0B
$-202.6M
Q1 25
$1.0B
$-205.0M
Q4 24
$1.0B
$-114.2M
Q3 24
$975.6M
$-105.1M
Q2 24
$934.9M
$-346.8M
Q1 24
$901.7M
$-257.2M
Total Assets
ACLS
ACLS
ASND
ASND
Q4 25
$1.4B
$1.4B
Q3 25
$1.4B
$1.2B
Q2 25
$1.3B
$1.2B
Q1 25
$1.3B
$1.1B
Q4 24
$1.3B
$1.3B
Q3 24
$1.3B
$1.2B
Q2 24
$1.3B
$819.0M
Q1 24
$1.3B
$866.7M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ACLS
ACLS
ASND
ASND
Operating Cash FlowLast quarter
$-6.6M
$58.2M
Free Cash FlowOCF − Capex
$-8.9M
FCF MarginFCF / Revenue
-3.7%
Capex IntensityCapex / Revenue
1.0%
Cash ConversionOCF / Net Profit
-0.19×
TTM Free Cash FlowTrailing 4 quarters
$107.0M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ACLS
ACLS
ASND
ASND
Q4 25
$-6.6M
$58.2M
Q3 25
$45.4M
Q2 25
$39.7M
Q1 25
$39.8M
$-15.5M
Q4 24
$12.8M
$-330.7M
Q3 24
$45.7M
Q2 24
$40.1M
Q1 24
$42.2M
$-109.7M
Free Cash Flow
ACLS
ACLS
ASND
ASND
Q4 25
$-8.9M
Q3 25
$43.3M
Q2 25
$37.7M
Q1 25
$34.8M
Q4 24
$8.1M
Q3 24
$41.8M
Q2 24
$38.1M
Q1 24
$40.6M
FCF Margin
ACLS
ACLS
ASND
ASND
Q4 25
-3.7%
Q3 25
20.3%
Q2 25
19.4%
Q1 25
18.1%
Q4 24
3.2%
Q3 24
16.3%
Q2 24
14.8%
Q1 24
16.1%
Capex Intensity
ACLS
ACLS
ASND
ASND
Q4 25
1.0%
Q3 25
0.9%
Q2 25
1.0%
Q1 25
2.6%
Q4 24
1.8%
Q3 24
1.5%
Q2 24
0.8%
Q1 24
0.6%
Cash Conversion
ACLS
ACLS
ASND
ASND
Q4 25
-0.19×
Q3 25
1.75×
Q2 25
1.27×
Q1 25
1.39×
Q4 24
0.26×
Q3 24
0.94×
Q2 24
0.79×
Q1 24
0.82×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

ACLS
ACLS

Products$224.6M94%
Services$13.7M6%

ASND
ASND

Segment breakdown not available.

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