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Side-by-side financial comparison of Aclarion, Inc. (ACON) and GRAIL, Inc. (GRAL). Click either name above to swap in a different company.

GRAIL, Inc. is the larger business by last-quarter revenue ($43.6M vs $18.5K, roughly 2359.4× Aclarion, Inc.). GRAIL, Inc. runs the higher net margin — -227.5% vs -10223.7%, a 9996.3% gap on every dollar of revenue. On growth, Aclarion, Inc. posted the faster year-over-year revenue change (80.6% vs 14.0%). Over the past eight quarters, Aclarion, Inc.'s revenue compounded faster (35.2% CAGR vs 27.7%).

Aclarion, Inc. is a medical technology company focused on developing non-invasive solutions for chronic lower back pain diagnosis and treatment. Its core offerings leverage proprietary magnetic resonance spectroscopy technology to accurately identify painful intervertebral discs, serving healthcare providers and patients across the United States, with key focus on the chronic pain management and spinal care segments.

GRAIL, Inc. is an American biotechnology company based in Menlo Park, California founded in 2015 seeking to develop an early cancer screening test for people who do not have symptoms. As a startup it was a subsidiary of Illumina, which bought it outright in 2021.

ACON vs GRAL — Head-to-Head

Bigger by revenue
GRAL
GRAL
2359.4× larger
GRAL
$43.6M
$18.5K
ACON
Growing faster (revenue YoY)
ACON
ACON
+66.6% gap
ACON
80.6%
14.0%
GRAL
Higher net margin
GRAL
GRAL
9996.3% more per $
GRAL
-227.5%
-10223.7%
ACON
Faster 2-yr revenue CAGR
ACON
ACON
Annualised
ACON
35.2%
27.7%
GRAL

Income Statement — Q4 2025 vs Q4 2025

Metric
ACON
ACON
GRAL
GRAL
Revenue
$18.5K
$43.6M
Net Profit
$-1.9M
$-99.2M
Gross Margin
9.7%
Operating Margin
-10785.8%
-285.4%
Net Margin
-10223.7%
-227.5%
Revenue YoY
80.6%
14.0%
Net Profit YoY
5.0%
-2.2%
EPS (diluted)
$1.39
$-2.37

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ACON
ACON
GRAL
GRAL
Q4 25
$18.5K
$43.6M
Q3 25
$18.9K
$36.2M
Q2 25
$19.3K
$35.5M
Q1 25
$19.0K
$31.8M
Q4 24
$10.2K
$38.3M
Q3 24
$14.4K
$28.7M
Q2 24
$11.0K
$32.0M
Q1 24
$10.1K
$26.7M
Net Profit
ACON
ACON
GRAL
GRAL
Q4 25
$-1.9M
$-99.2M
Q3 25
$-1.7M
$-89.0M
Q2 25
$-1.6M
$-114.0M
Q1 25
$-2.0M
$-106.2M
Q4 24
$-2.0M
$-97.1M
Q3 24
$-1.4M
$-125.7M
Q2 24
$-1.2M
$-1.6B
Q1 24
$-2.4M
$-218.9M
Gross Margin
ACON
ACON
GRAL
GRAL
Q4 25
9.7%
Q3 25
23.2%
Q2 25
26.6%
Q1 25
-23.6%
Q4 24
-100.9%
Q3 24
-48.1%
Q2 24
-112.3%
Q1 24
-92.6%
Operating Margin
ACON
ACON
GRAL
GRAL
Q4 25
-10785.8%
-285.4%
Q3 25
-9666.2%
-346.2%
Q2 25
-8988.6%
-446.9%
Q1 25
-7856.0%
-482.5%
Q4 24
-17652.7%
-358.0%
Q3 24
-8995.3%
-640.5%
Q2 24
-10350.6%
-5133.8%
Q1 24
-12609.3%
-851.1%
Net Margin
ACON
ACON
GRAL
GRAL
Q4 25
-10223.7%
-227.5%
Q3 25
-9008.0%
-245.8%
Q2 25
-8285.9%
-320.7%
Q1 25
-10728.4%
-333.6%
Q4 24
-19444.6%
-253.8%
Q3 24
-9482.7%
-438.7%
Q2 24
-11285.0%
-4958.8%
Q1 24
-23720.6%
-819.3%
EPS (diluted)
ACON
ACON
GRAL
GRAL
Q4 25
$1.39
$-2.37
Q3 25
$-2.93
$-2.46
Q2 25
$-2.75
$-3.18
Q1 25
$-9.32
$-3.10
Q4 24
$-809.36
$-1.49
Q3 24
$-1321.49
$-3.94
Q2 24
$-1362.83
$-51.06
Q1 24
$-3985.22
$-7.05

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ACON
ACON
GRAL
GRAL
Cash + ST InvestmentsLiquidity on hand
$12.0M
$249.7M
Total DebtLower is stronger
Stockholders' EquityBook value
$12.8M
$2.6B
Total Assets
$13.7M
$2.9B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ACON
ACON
GRAL
GRAL
Q4 25
$12.0M
$249.7M
Q3 25
$11.3M
$126.9M
Q2 25
$12.8M
$127.4M
Q1 25
$14.8M
$133.9M
Q4 24
$453.7K
$214.2M
Q3 24
$1.3M
$853.6M
Q2 24
$1.2M
$958.8M
Q1 24
$2.1M
$199.7M
Stockholders' Equity
ACON
ACON
GRAL
GRAL
Q4 25
$12.8M
$2.6B
Q3 25
$12.5M
$2.2B
Q2 25
$14.2M
$2.3B
Q1 25
$15.8M
$2.4B
Q4 24
$970.1K
$2.5B
Q3 24
$2.5M
$2.6B
Q2 24
$1.6M
$2.7B
Q1 24
$2.5M
Total Assets
ACON
ACON
GRAL
GRAL
Q4 25
$13.7M
$2.9B
Q3 25
$13.2M
$2.6B
Q2 25
$14.8M
$2.7B
Q1 25
$16.5M
$2.8B
Q4 24
$2.1M
$3.0B
Q3 24
$3.2M
$3.1B
Q2 24
$3.1M
$3.3B
Q1 24
$3.7M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ACON
ACON
GRAL
GRAL
Operating Cash FlowLast quarter
$-1.6M
$-63.8M
Free Cash FlowOCF − Capex
$-63.9M
FCF MarginFCF / Revenue
-146.5%
Capex IntensityCapex / Revenue
0.2%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-299.9M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ACON
ACON
GRAL
GRAL
Q4 25
$-1.6M
$-63.8M
Q3 25
$-1.2M
$-63.2M
Q2 25
$-1.9M
$-77.0M
Q1 25
$-2.5M
$-95.0M
Q4 24
$-922.9K
Q3 24
$-1.1M
$-104.6M
Q2 24
$-1.1M
$-171.8M
Q1 24
$-2.2M
$-207.3M
Free Cash Flow
ACON
ACON
GRAL
GRAL
Q4 25
$-63.9M
Q3 25
$-1.2M
$-63.6M
Q2 25
$-77.3M
Q1 25
$-95.1M
Q4 24
Q3 24
$-105.6M
Q2 24
$-173.2M
Q1 24
$-209.8M
FCF Margin
ACON
ACON
GRAL
GRAL
Q4 25
-146.5%
Q3 25
-6164.6%
-175.8%
Q2 25
-217.6%
Q1 25
-298.6%
Q4 24
Q3 24
-368.4%
Q2 24
-541.7%
Q1 24
-785.3%
Capex Intensity
ACON
ACON
GRAL
GRAL
Q4 25
0.2%
Q3 25
38.6%
1.1%
Q2 25
1.0%
Q1 25
0.2%
Q4 24
Q3 24
0.0%
3.4%
Q2 24
4.3%
Q1 24
9.5%

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

ACON
ACON

Segment breakdown not available.

GRAL
GRAL

Screening Revenue$42.3M97%
Developmental Services Revenue$1.3M3%

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