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Side-by-side financial comparison of Adagene Inc. (ADAG) and Align Technology (ALGN). Click either name above to swap in a different company.

Adagene Inc. is a global clinical-stage biotechnology company specializing in the research, development, and commercialization of innovative antibody-based cancer immunotherapies. Leveraging its proprietary next-generation antibody technology platforms, it develops targeted oncology treatments for patients across global markets, with core R&D bases in China and clinical programs covering North America, Asia, and Europe.

Align Technology, Inc., a medical device company, designs, manufactures, and markets Invisalign clear aligners and iTero intraoral scanners and services for orthodontists and general practitioner dentists, and restorative and aesthetic dentistry. It operates in two segments, Clear Aligner; and Scanners and Services. The Clear Aligner segment consists of comprehensive products, including Invisalign comprehensive treatment that addresses the orthodontic needs of teenage patients, such as mandib...

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ADAG
ADAG
ALGN
ALGN
Q4 25
$1.0B
Q3 25
$995.7M
Q2 25
$1.0B
Q1 25
$979.3M
Q4 24
$995.2M
Q3 24
$977.9M
Q2 24
$1.0B
Q1 24
$997.4M
Net Profit
ADAG
ADAG
ALGN
ALGN
Q4 25
$135.8M
Q3 25
$56.8M
Q2 25
$124.6M
Q1 25
$93.2M
Q4 24
$103.8M
Q3 24
$116.0M
Q2 24
$96.6M
Q1 24
$105.0M
Gross Margin
ADAG
ADAG
ALGN
ALGN
Q4 25
65.3%
Q3 25
64.2%
Q2 25
69.9%
Q1 25
69.5%
Q4 24
70.0%
Q3 24
69.7%
Q2 24
70.3%
Q1 24
70.0%
Operating Margin
ADAG
ADAG
ALGN
ALGN
Q4 25
14.8%
Q3 25
9.7%
Q2 25
16.1%
Q1 25
13.4%
Q4 24
14.5%
Q3 24
16.6%
Q2 24
14.3%
Q1 24
15.5%
Net Margin
ADAG
ADAG
ALGN
ALGN
Q4 25
13.0%
Q3 25
5.7%
Q2 25
12.3%
Q1 25
9.5%
Q4 24
10.4%
Q3 24
11.9%
Q2 24
9.4%
Q1 24
10.5%
EPS (diluted)
ADAG
ADAG
ALGN
ALGN
Q4 25
$1.88
Q3 25
$0.78
Q2 25
$1.72
Q1 25
$1.27
Q4 24
$1.40
Q3 24
$1.55
Q2 24
$1.28
Q1 24
$1.39

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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