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Side-by-side financial comparison of Adaptive Biotechnologies Corp (ADPT) and Twist Bioscience Corp (TWST). Click either name above to swap in a different company.
Twist Bioscience Corp is the larger business by last-quarter revenue ($103.7M vs $70.9M, roughly 1.5× Adaptive Biotechnologies Corp). Adaptive Biotechnologies Corp runs the higher net margin — 4.7% vs -29.4%, a 34.2% gap on every dollar of revenue. On growth, Adaptive Biotechnologies Corp posted the faster year-over-year revenue change (35.1% vs 16.9%).
ExpreS2ion Biotechnologies is a Danish biotechnology company specialised in the development of new vaccines and immunotherapy products based in Hørsholm, Denmark and listed on the Nasdaq First North Growth Market Sweden.
Twist Bioscience is a public biotechnology company based in South San Francisco that manufactures synthetic DNA and DNA products for customers in a wide range of industries. Twist was founded in 2013 by Emily Leproust, Bill Banyai, and Bill Peck.
ADPT vs TWST — Head-to-Head
Income Statement — Q1 FY2026 vs Q1 FY2026
| Metric | | |
|---|---|---|
| Revenue | $70.9M | $103.7M |
| Net Profit | $3.4M | $-30.5M |
| Gross Margin | 73.6% | 52.0% |
| Operating Margin | -27.1% | -31.7% |
| Net Margin | 4.7% | -29.4% |
| Revenue YoY | 35.1% | 16.9% |
| Net Profit YoY | — | 3.4% |
| EPS (diluted) | — | $-0.50 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q1 26 | $70.9M | — | ||
| Q4 25 | $71.7M | $103.7M | ||
| Q3 25 | $94.0M | — | ||
| Q2 25 | $58.9M | — | ||
| Q1 25 | $52.4M | — | ||
| Q4 24 | $47.5M | — | ||
| Q3 24 | $46.4M | — | ||
| Q2 24 | $43.2M | — |
| Q1 26 | $3.4M | — | ||
| Q4 25 | $-13.6M | $-30.5M | ||
| Q3 25 | $9.5M | — | ||
| Q2 25 | $-25.6M | — | ||
| Q1 25 | $-29.9M | — | ||
| Q4 24 | $-33.7M | — | ||
| Q3 24 | $-32.1M | — | ||
| Q2 24 | $-46.2M | — |
| Q1 26 | 73.6% | — | ||
| Q4 25 | 74.6% | 52.0% | ||
| Q3 25 | 80.7% | — | ||
| Q2 25 | 69.4% | — | ||
| Q1 25 | 67.6% | — | ||
| Q4 24 | 62.0% | — | ||
| Q3 24 | 64.1% | — | ||
| Q2 24 | 55.3% | — |
| Q1 26 | -27.1% | — | ||
| Q4 25 | -17.8% | -31.7% | ||
| Q3 25 | 10.9% | — | ||
| Q2 25 | -42.5% | — | ||
| Q1 25 | -56.4% | — | ||
| Q4 24 | -71.3% | — | ||
| Q3 24 | -70.3% | — | ||
| Q2 24 | -109.6% | — |
| Q1 26 | 4.7% | — | ||
| Q4 25 | -18.9% | -29.4% | ||
| Q3 25 | 10.2% | — | ||
| Q2 25 | -43.5% | — | ||
| Q1 25 | -56.9% | — | ||
| Q4 24 | -71.0% | — | ||
| Q3 24 | -69.1% | — | ||
| Q2 24 | -107.0% | — |
| Q1 26 | — | — | ||
| Q4 25 | $-0.08 | $-0.50 | ||
| Q3 25 | $0.06 | — | ||
| Q2 25 | $-0.17 | — | ||
| Q1 25 | $-0.20 | — | ||
| Q4 24 | $-0.22 | — | ||
| Q3 24 | $-0.22 | — | ||
| Q2 24 | $-0.31 | — |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $77.6M | $197.9M |
| Total DebtLower is stronger | — | — |
| Stockholders' EquityBook value | — | $456.1M |
| Total Assets | $505.9M | $638.1M |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q1 26 | $77.6M | — | ||
| Q4 25 | $70.5M | $197.9M | ||
| Q3 25 | $55.0M | — | ||
| Q2 25 | $43.2M | — | ||
| Q1 25 | $50.6M | — | ||
| Q4 24 | $47.9M | — | ||
| Q3 24 | $38.1M | — | ||
| Q2 24 | $59.8M | — |
| Q1 26 | — | — | ||
| Q4 25 | $218.8M | $456.1M | ||
| Q3 25 | $204.4M | — | ||
| Q2 25 | $179.7M | — | ||
| Q1 25 | $190.4M | — | ||
| Q4 24 | $202.7M | — | ||
| Q3 24 | $223.8M | — | ||
| Q2 24 | $241.6M | — |
| Q1 26 | $505.9M | — | ||
| Q4 25 | $512.7M | $638.1M | ||
| Q3 25 | $490.6M | — | ||
| Q2 25 | $496.6M | — | ||
| Q1 25 | $510.9M | — | ||
| Q4 24 | $539.4M | — | ||
| Q3 24 | $558.5M | — | ||
| Q2 24 | $584.9M | — |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | — | $-24.8M |
| Free Cash FlowOCF − Capex | — | $-34.8M |
| FCF MarginFCF / Revenue | — | -33.5% |
| Capex IntensityCapex / Revenue | — | 9.6% |
| Cash ConversionOCF / Net Profit | — | — |
| TTM Free Cash FlowTrailing 4 quarters | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q1 26 | — | — | ||
| Q4 25 | $2.1M | $-24.8M | ||
| Q3 25 | $-7.1M | — | ||
| Q2 25 | $-12.4M | — | ||
| Q1 25 | $-28.5M | — | ||
| Q4 24 | $-12.5M | — | ||
| Q3 24 | $-27.1M | — | ||
| Q2 24 | $-17.3M | — |
| Q1 26 | — | — | ||
| Q4 25 | $1.4M | $-34.8M | ||
| Q3 25 | $-7.5M | — | ||
| Q2 25 | $-13.1M | — | ||
| Q1 25 | $-29.7M | — | ||
| Q4 24 | $-12.6M | — | ||
| Q3 24 | $-27.4M | — | ||
| Q2 24 | $-19.0M | — |
| Q1 26 | — | — | ||
| Q4 25 | 2.0% | -33.5% | ||
| Q3 25 | -8.0% | — | ||
| Q2 25 | -22.2% | — | ||
| Q1 25 | -56.7% | — | ||
| Q4 24 | -26.5% | — | ||
| Q3 24 | -59.0% | — | ||
| Q2 24 | -44.1% | — |
| Q1 26 | — | — | ||
| Q4 25 | 0.9% | 9.6% | ||
| Q3 25 | 0.4% | — | ||
| Q2 25 | 1.1% | — | ||
| Q1 25 | 2.4% | — | ||
| Q4 24 | 0.2% | — | ||
| Q3 24 | 0.7% | — | ||
| Q2 24 | 4.0% | — |
| Q1 26 | — | — | ||
| Q4 25 | — | — | ||
| Q3 25 | -0.75× | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | — | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
ADPT
Segment breakdown not available.
TWST
| Industrial Chemicals | $37.2M | 36% |
| Diagnostics | $35.3M | 34% |
| Food Or Agriculture | $12.8M | 12% |
| Academic Research | $12.2M | 12% |
| Health Care | $6.1M | 6% |
