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Side-by-side financial comparison of C3.ai, Inc. (AI) and OPKO HEALTH, INC. (OPK). Click either name above to swap in a different company.
OPKO HEALTH, INC. is the larger business by last-quarter revenue ($148.5M vs $75.1M, roughly 2.0× C3.ai, Inc.). OPKO HEALTH, INC. runs the higher net margin — -21.1% vs -139.3%, a 118.2% gap on every dollar of revenue. On growth, OPKO HEALTH, INC. posted the faster year-over-year revenue change (-19.2% vs -20.3%). OPKO HEALTH, INC. produced more free cash flow last quarter ($-28.6M vs $-46.9M). Over the past eight quarters, C3.ai, Inc.'s revenue compounded faster (-2.1% CAGR vs -7.5%).
C3.ai, Inc. is a leading enterprise artificial intelligence software provider that develops and delivers scalable AI applications, platform tools, and industry-specific solutions for clients across sectors including manufacturing, energy, financial services, healthcare and public sector. Its offerings help organizations optimize operations, reduce costs, mitigate risks, and realize data-driven decision making.
OPKO Health, Inc. is a medical test and medication company focused on diagnostics and pharmaceuticals. The company is a publicly traded company on NASDAQ and TASE under the symbol "OPK".
AI vs OPK — Head-to-Head
Income Statement — Q2 FY2026 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $75.1M | $148.5M |
| Net Profit | $-104.7M | $-31.3M |
| Gross Margin | 40.4% | 43.1% |
| Operating Margin | -149.2% | -25.8% |
| Net Margin | -139.3% | -21.1% |
| Revenue YoY | -20.3% | -19.2% |
| Net Profit YoY | -58.7% | -322.8% |
| EPS (diluted) | $-0.75 | $-0.04 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $75.1M | $148.5M | ||
| Q3 25 | $70.3M | $151.7M | ||
| Q2 25 | $108.7M | $156.8M | ||
| Q1 25 | $98.8M | $150.0M | ||
| Q4 24 | $94.3M | $183.6M | ||
| Q3 24 | $87.2M | $173.6M | ||
| Q2 24 | $86.6M | $182.2M | ||
| Q1 24 | $78.4M | $173.7M |
| Q4 25 | $-104.7M | $-31.3M | ||
| Q3 25 | $-116.8M | $21.6M | ||
| Q2 25 | $-79.7M | $-148.4M | ||
| Q1 25 | $-80.2M | $-67.6M | ||
| Q4 24 | $-66.0M | $14.0M | ||
| Q3 24 | $-62.8M | $24.9M | ||
| Q2 24 | $-72.9M | $-10.3M | ||
| Q1 24 | $-72.6M | $-81.8M |
| Q4 25 | 40.4% | 43.1% | ||
| Q3 25 | 37.6% | 32.9% | ||
| Q2 25 | 62.1% | 31.5% | ||
| Q1 25 | 59.1% | 28.4% | ||
| Q4 24 | 61.3% | 46.1% | ||
| Q3 24 | 59.8% | 23.1% | ||
| Q2 24 | 59.6% | 28.4% | ||
| Q1 24 | 57.8% | 24.2% |
| Q4 25 | -149.2% | -25.8% | ||
| Q3 25 | -177.7% | 31.7% | ||
| Q2 25 | -81.8% | -38.3% | ||
| Q1 25 | -88.7% | -44.8% | ||
| Q4 24 | -79.8% | -18.0% | ||
| Q3 24 | -83.2% | 8.2% | ||
| Q2 24 | -95.1% | -33.9% | ||
| Q1 24 | -105.3% | -41.2% |
| Q4 25 | -139.3% | -21.1% | ||
| Q3 25 | -166.2% | 14.3% | ||
| Q2 25 | -73.3% | -94.7% | ||
| Q1 25 | -81.2% | -45.1% | ||
| Q4 24 | -69.9% | 7.6% | ||
| Q3 24 | -72.0% | 14.3% | ||
| Q2 24 | -84.2% | -5.7% | ||
| Q1 24 | -92.6% | -47.1% |
| Q4 25 | $-0.75 | $-0.04 | ||
| Q3 25 | $-0.86 | $0.03 | ||
| Q2 25 | $-0.60 | $-0.19 | ||
| Q1 25 | $-0.62 | $-0.10 | ||
| Q4 24 | $-0.52 | $0.02 | ||
| Q3 24 | $-0.50 | $0.03 | ||
| Q2 24 | $-0.59 | $-0.01 | ||
| Q1 24 | $-0.60 | $-0.12 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $675.0M | $364.4M |
| Total DebtLower is stronger | — | $344.0M |
| Stockholders' EquityBook value | $771.9M | $1.3B |
| Total Assets | $961.3M | $1.9B |
| Debt / EquityLower = less leverage | — | 0.27× |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $675.0M | $364.4M | ||
| Q3 25 | $711.9M | $412.0M | ||
| Q2 25 | $742.7M | $267.3M | ||
| Q1 25 | $724.3M | $428.8M | ||
| Q4 24 | $730.4M | $426.6M | ||
| Q3 24 | $762.5M | $400.1M | ||
| Q2 24 | $750.4M | $40.6M | ||
| Q1 24 | $723.3M | $75.6M |
| Q4 25 | — | $344.0M | ||
| Q3 25 | — | $344.2M | ||
| Q2 25 | — | $343.3M | ||
| Q1 25 | — | $439.2M | ||
| Q4 24 | — | $437.2M | ||
| Q3 24 | — | $441.0M | ||
| Q2 24 | — | $201.9M | ||
| Q1 24 | — | $350.1M |
| Q4 25 | $771.9M | $1.3B | ||
| Q3 25 | $798.8M | $1.3B | ||
| Q2 25 | $838.3M | $1.3B | ||
| Q1 25 | $860.2M | $1.3B | ||
| Q4 24 | $859.0M | $1.4B | ||
| Q3 24 | $874.9M | $1.4B | ||
| Q2 24 | $873.4M | $1.4B | ||
| Q1 24 | $898.0M | $1.3B |
| Q4 25 | $961.3M | $1.9B | ||
| Q3 25 | $968.7M | $2.0B | ||
| Q2 25 | $1.0B | $2.0B | ||
| Q1 25 | $1.1B | $2.1B | ||
| Q4 24 | $1.0B | $2.2B | ||
| Q3 24 | $1.1B | $2.3B | ||
| Q2 24 | $1.0B | $2.0B | ||
| Q1 24 | $1.1B | $2.0B |
| Q4 25 | — | 0.27× | ||
| Q3 25 | — | 0.26× | ||
| Q2 25 | — | 0.26× | ||
| Q1 25 | — | 0.33× | ||
| Q4 24 | — | 0.32× | ||
| Q3 24 | — | 0.31× | ||
| Q2 24 | — | 0.14× | ||
| Q1 24 | — | 0.28× |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-46.5M | $-25.9M |
| Free Cash FlowOCF − Capex | $-46.9M | $-28.6M |
| FCF MarginFCF / Revenue | -62.4% | -19.3% |
| Capex IntensityCapex / Revenue | 0.5% | 1.8% |
| Cash ConversionOCF / Net Profit | — | — |
| TTM Free Cash FlowTrailing 4 quarters | $-93.2M | $-190.8M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-46.5M | $-25.9M | ||
| Q3 25 | $-33.5M | $-34.6M | ||
| Q2 25 | $11.3M | $-83.4M | ||
| Q1 25 | $-22.0M | $-34.6M | ||
| Q4 24 | $-38.7M | $-44.4M | ||
| Q3 24 | $8.0M | $-77.1M | ||
| Q2 24 | $21.3M | $-26.4M | ||
| Q1 24 | $-39.1M | $-35.6M |
| Q4 25 | $-46.9M | $-28.6M | ||
| Q3 25 | $-34.3M | $-37.8M | ||
| Q2 25 | $10.3M | $-86.7M | ||
| Q1 25 | $-22.4M | $-37.7M | ||
| Q4 24 | $-39.5M | $-49.8M | ||
| Q3 24 | $7.1M | $-85.0M | ||
| Q2 24 | $18.8M | $-33.7M | ||
| Q1 24 | $-45.1M | $-40.0M |
| Q4 25 | -62.4% | -19.3% | ||
| Q3 25 | -48.8% | -24.9% | ||
| Q2 25 | 9.5% | -55.3% | ||
| Q1 25 | -22.7% | -25.2% | ||
| Q4 24 | -41.9% | -27.1% | ||
| Q3 24 | 8.2% | -49.0% | ||
| Q2 24 | 21.7% | -18.5% | ||
| Q1 24 | -57.6% | -23.0% |
| Q4 25 | 0.5% | 1.8% | ||
| Q3 25 | 1.1% | 2.1% | ||
| Q2 25 | 0.9% | 2.1% | ||
| Q1 25 | 0.4% | 2.1% | ||
| Q4 24 | 0.9% | 2.9% | ||
| Q3 24 | 1.1% | 4.6% | ||
| Q2 24 | 2.9% | 4.0% | ||
| Q1 24 | 7.8% | 2.6% |
| Q4 25 | — | — | ||
| Q3 25 | — | -1.60× | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | -3.17× | ||
| Q3 24 | — | -3.10× | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
AI
| License And Service | $70.2M | 93% |
| Professional Services | $4.9M | 7% |
OPK
| Services | $71.1M | 48% |
| Transfer Of Intellectual Property And Other | $33.7M | 23% |
| IE | $22.1M | 15% |
| Rayaldee | $8.8M | 6% |
| Barda Agreement | $6.8M | 5% |
| MX | $6.3M | 4% |
