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Side-by-side financial comparison of Astera Labs, Inc. (ALAB) and OPKO HEALTH, INC. (OPK). Click either name above to swap in a different company.
Astera Labs, Inc. is the larger business by last-quarter revenue ($270.6M vs $148.5M, roughly 1.8× OPKO HEALTH, INC.). Astera Labs, Inc. runs the higher net margin — 16.6% vs -21.1%, a 37.7% gap on every dollar of revenue. On growth, Astera Labs, Inc. posted the faster year-over-year revenue change (91.8% vs -19.2%). Astera Labs, Inc. produced more free cash flow last quarter ($76.6M vs $-28.6M). Over the past eight quarters, Astera Labs, Inc.'s revenue compounded faster (103.6% CAGR vs -7.5%).
Astera Labs, Inc. is an American fabless semiconductor manufacturer and artificial intelligence company. The company specializes in designing high-speed connectivity solutions for data centers and AI infrastructure. The company has been listed on the Nasdaq since March 2024.
OPKO Health, Inc. is a medical test and medication company focused on diagnostics and pharmaceuticals. The company is a publicly traded company on NASDAQ and TASE under the symbol "OPK".
ALAB vs OPK — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $270.6M | $148.5M |
| Net Profit | $45.0M | $-31.3M |
| Gross Margin | 75.6% | 43.1% |
| Operating Margin | 24.7% | -25.8% |
| Net Margin | 16.6% | -21.1% |
| Revenue YoY | 91.8% | -19.2% |
| Net Profit YoY | 82.0% | -322.8% |
| EPS (diluted) | $0.25 | $-0.04 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $270.6M | $148.5M | ||
| Q3 25 | $230.6M | $151.7M | ||
| Q2 25 | $191.9M | $156.8M | ||
| Q1 25 | $159.4M | $150.0M | ||
| Q4 24 | $141.1M | $183.6M | ||
| Q3 24 | $113.1M | $173.6M | ||
| Q2 24 | $76.8M | $182.2M | ||
| Q1 24 | $65.3M | $173.7M |
| Q4 25 | $45.0M | $-31.3M | ||
| Q3 25 | $91.1M | $21.6M | ||
| Q2 25 | $51.2M | $-148.4M | ||
| Q1 25 | $31.8M | $-67.6M | ||
| Q4 24 | $24.7M | $14.0M | ||
| Q3 24 | $-7.6M | $24.9M | ||
| Q2 24 | $-7.5M | $-10.3M | ||
| Q1 24 | $-93.0M | $-81.8M |
| Q4 25 | 75.6% | 43.1% | ||
| Q3 25 | 76.2% | 32.9% | ||
| Q2 25 | 75.8% | 31.5% | ||
| Q1 25 | 74.9% | 28.4% | ||
| Q4 24 | 74.0% | 46.1% | ||
| Q3 24 | 77.7% | 23.1% | ||
| Q2 24 | 77.9% | 28.4% | ||
| Q1 24 | 77.4% | 24.2% |
| Q4 25 | 24.7% | -25.8% | ||
| Q3 25 | 24.0% | 31.7% | ||
| Q2 25 | 20.7% | -38.3% | ||
| Q1 25 | 7.1% | -44.8% | ||
| Q4 24 | 0.1% | -18.0% | ||
| Q3 24 | -7.9% | 8.2% | ||
| Q2 24 | -31.7% | -33.9% | ||
| Q1 24 | -127.1% | -41.2% |
| Q4 25 | 16.6% | -21.1% | ||
| Q3 25 | 39.5% | 14.3% | ||
| Q2 25 | 26.7% | -94.7% | ||
| Q1 25 | 20.0% | -45.1% | ||
| Q4 24 | 17.5% | 7.6% | ||
| Q3 24 | -6.7% | 14.3% | ||
| Q2 24 | -9.8% | -5.7% | ||
| Q1 24 | -142.5% | -47.1% |
| Q4 25 | $0.25 | $-0.04 | ||
| Q3 25 | $0.50 | $0.03 | ||
| Q2 25 | $0.29 | $-0.19 | ||
| Q1 25 | $0.18 | $-0.10 | ||
| Q4 24 | $1.23 | $0.02 | ||
| Q3 24 | $-0.05 | $0.03 | ||
| Q2 24 | $-0.05 | $-0.01 | ||
| Q1 24 | $-1.77 | $-0.12 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $167.6M | $364.4M |
| Total DebtLower is stronger | — | $344.0M |
| Stockholders' EquityBook value | $1.4B | $1.3B |
| Total Assets | $1.5B | $1.9B |
| Debt / EquityLower = less leverage | — | 0.27× |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $167.6M | $364.4M | ||
| Q3 25 | $140.4M | $412.0M | ||
| Q2 25 | $162.3M | $267.3M | ||
| Q1 25 | $86.4M | $428.8M | ||
| Q4 24 | $79.6M | $426.6M | ||
| Q3 24 | $126.1M | $400.1M | ||
| Q2 24 | $421.1M | $40.6M | ||
| Q1 24 | $696.1M | $75.6M |
| Q4 25 | — | $344.0M | ||
| Q3 25 | — | $344.2M | ||
| Q2 25 | — | $343.3M | ||
| Q1 25 | — | $439.2M | ||
| Q4 24 | — | $437.2M | ||
| Q3 24 | — | $441.0M | ||
| Q2 24 | — | $201.9M | ||
| Q1 24 | — | $350.1M |
| Q4 25 | $1.4B | $1.3B | ||
| Q3 25 | $1.3B | $1.3B | ||
| Q2 25 | $1.1B | $1.3B | ||
| Q1 25 | $1.0B | $1.3B | ||
| Q4 24 | $964.8M | $1.4B | ||
| Q3 24 | $889.6M | $1.4B | ||
| Q2 24 | $845.3M | $1.4B | ||
| Q1 24 | $808.8M | $1.3B |
| Q4 25 | $1.5B | $1.9B | ||
| Q3 25 | $1.4B | $2.0B | ||
| Q2 25 | $1.3B | $2.0B | ||
| Q1 25 | $1.1B | $2.1B | ||
| Q4 24 | $1.1B | $2.2B | ||
| Q3 24 | $983.1M | $2.3B | ||
| Q2 24 | $915.5M | $2.0B | ||
| Q1 24 | $864.9M | $2.0B |
| Q4 25 | — | 0.27× | ||
| Q3 25 | — | 0.26× | ||
| Q2 25 | — | 0.26× | ||
| Q1 25 | — | 0.33× | ||
| Q4 24 | — | 0.32× | ||
| Q3 24 | — | 0.31× | ||
| Q2 24 | — | 0.14× | ||
| Q1 24 | — | 0.28× |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $95.3M | $-25.9M |
| Free Cash FlowOCF − Capex | $76.6M | $-28.6M |
| FCF MarginFCF / Revenue | 28.3% | -19.3% |
| Capex IntensityCapex / Revenue | 6.9% | 1.8% |
| Cash ConversionOCF / Net Profit | 2.12× | — |
| TTM Free Cash FlowTrailing 4 quarters | $281.8M | $-190.8M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $95.3M | $-25.9M | ||
| Q3 25 | $78.2M | $-34.6M | ||
| Q2 25 | $135.4M | $-83.4M | ||
| Q1 25 | $10.5M | $-34.6M | ||
| Q4 24 | $39.7M | $-44.4M | ||
| Q3 24 | $63.5M | $-77.1M | ||
| Q2 24 | $29.8M | $-26.4M | ||
| Q1 24 | $3.7M | $-35.6M |
| Q4 25 | $76.6M | $-28.6M | ||
| Q3 25 | $65.9M | $-37.8M | ||
| Q2 25 | $133.3M | $-86.7M | ||
| Q1 25 | $6.0M | $-37.7M | ||
| Q4 24 | $24.3M | $-49.8M | ||
| Q3 24 | $46.8M | $-85.0M | ||
| Q2 24 | $28.5M | $-33.7M | ||
| Q1 24 | $228.0K | $-40.0M |
| Q4 25 | 28.3% | -19.3% | ||
| Q3 25 | 28.6% | -24.9% | ||
| Q2 25 | 69.5% | -55.3% | ||
| Q1 25 | 3.7% | -25.2% | ||
| Q4 24 | 17.2% | -27.1% | ||
| Q3 24 | 41.4% | -49.0% | ||
| Q2 24 | 37.1% | -18.5% | ||
| Q1 24 | 0.3% | -23.0% |
| Q4 25 | 6.9% | 1.8% | ||
| Q3 25 | 5.3% | 2.1% | ||
| Q2 25 | 1.1% | 2.1% | ||
| Q1 25 | 2.8% | 2.1% | ||
| Q4 24 | 10.9% | 2.9% | ||
| Q3 24 | 14.8% | 4.6% | ||
| Q2 24 | 1.7% | 4.0% | ||
| Q1 24 | 5.2% | 2.6% |
| Q4 25 | 2.12× | — | ||
| Q3 25 | 0.86× | -1.60× | ||
| Q2 25 | 2.64× | — | ||
| Q1 25 | 0.33× | — | ||
| Q4 24 | 1.61× | -3.17× | ||
| Q3 24 | — | -3.10× | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
ALAB
Segment breakdown not available.
OPK
| Services | $71.1M | 48% |
| Transfer Of Intellectual Property And Other | $33.7M | 23% |
| IE | $22.1M | 15% |
| Rayaldee | $8.8M | 6% |
| Barda Agreement | $6.8M | 5% |
| MX | $6.3M | 4% |
