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Side-by-side financial comparison of Alkermes plc. (ALKS) and Hess Midstream LP (HESM). Click either name above to swap in a different company.

Alkermes plc. is the larger business by last-quarter revenue ($384.5M vs $204.1M, roughly 1.9× Hess Midstream LP). Hess Midstream LP runs the higher net margin — 77.3% vs 12.8%, a 64.4% gap on every dollar of revenue. On growth, Hess Midstream LP posted the faster year-over-year revenue change (2.1% vs -10.6%). Over the past eight quarters, Alkermes plc.'s revenue compounded faster (4.8% CAGR vs -25.3%).

Alkermes plc is a fully-integrated biopharmaceutical company that focuses on developing medicines for psychiatric and neurological disorders. The company was founded in 1987 by Michael Wall. In September 2011 Alkermes, Inc. merged with Elan Drug Technologies (EDT), the former drug formulation and manufacturing division of Élan Corporation, plc. The company is headquartered in Dublin, and has an R&D center in Waltham, Massachusetts, and a manufacturing facility in Wilmington, Ohio.

Hess Corporation is an American global independent energy company involved in the exploration and production of crude oil and natural gas. It was formed by the merger of Hess Oil and Chemical and Amerada Petroleum in 1968. Leon Hess was CEO from the early 1960s until 1995, after which his son John B Hess succeeded him as chairman and CEO. The company agreed to be acquired by rival oil company Chevron in October 2023, and the acquisition closed in July 2025.

ALKS vs HESM — Head-to-Head

Bigger by revenue
ALKS
ALKS
1.9× larger
ALKS
$384.5M
$204.1M
HESM
Growing faster (revenue YoY)
HESM
HESM
+12.7% gap
HESM
2.1%
-10.6%
ALKS
Higher net margin
HESM
HESM
64.4% more per $
HESM
77.3%
12.8%
ALKS
Faster 2-yr revenue CAGR
ALKS
ALKS
Annualised
ALKS
4.8%
-25.3%
HESM

Income Statement — Q4 FY2025 vs Q1 FY2026

Metric
ALKS
ALKS
HESM
HESM
Revenue
$384.5M
$204.1M
Net Profit
$49.3M
$157.7M
Gross Margin
88.0%
Operating Margin
15.1%
116.7%
Net Margin
12.8%
77.3%
Revenue YoY
-10.6%
2.1%
Net Profit YoY
-66.3%
-2.3%
EPS (diluted)
$0.29
$0.68

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ALKS
ALKS
HESM
HESM
Q1 26
$204.1M
Q4 25
$384.5M
$404.2M
Q3 25
$394.2M
$420.9M
Q2 25
$390.7M
$414.2M
Q1 25
$306.5M
$382.0M
Q4 24
$430.0M
$395.9M
Q3 24
$378.1M
$378.5M
Q2 24
$399.1M
$365.5M
Net Profit
ALKS
ALKS
HESM
HESM
Q1 26
$157.7M
Q4 25
$49.3M
$93.3M
Q3 25
$82.8M
$97.7M
Q2 25
$87.1M
$90.3M
Q1 25
$22.5M
$71.6M
Q4 24
$146.5M
$70.4M
Q3 24
$92.4M
$58.6M
Q2 24
$91.4M
$49.5M
Gross Margin
ALKS
ALKS
HESM
HESM
Q1 26
Q4 25
88.0%
Q3 25
86.9%
Q2 25
87.3%
Q1 25
83.9%
Q4 24
85.6%
Q3 24
83.3%
Q2 24
84.6%
Operating Margin
ALKS
ALKS
HESM
HESM
Q1 26
116.7%
Q4 25
15.1%
62.2%
Q3 25
22.6%
61.5%
Q2 25
23.8%
62.8%
Q1 25
4.5%
62.1%
Q4 24
37.8%
61.4%
Q3 24
27.7%
61.2%
Q2 24
27.5%
60.8%
Net Margin
ALKS
ALKS
HESM
HESM
Q1 26
77.3%
Q4 25
12.8%
23.1%
Q3 25
21.0%
23.2%
Q2 25
22.3%
21.8%
Q1 25
7.3%
18.7%
Q4 24
34.1%
17.8%
Q3 24
24.4%
15.5%
Q2 24
22.9%
13.5%
EPS (diluted)
ALKS
ALKS
HESM
HESM
Q1 26
$0.68
Q4 25
$0.29
Q3 25
$0.49
Q2 25
$0.52
Q1 25
$0.13
Q4 24
$0.88
Q3 24
$0.55
Q2 24
$0.53

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ALKS
ALKS
HESM
HESM
Cash + ST InvestmentsLiquidity on hand
$388.6M
Total DebtLower is stronger
Stockholders' EquityBook value
$1.8B
Total Assets
$2.5B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ALKS
ALKS
HESM
HESM
Q1 26
Q4 25
$388.6M
$1.9M
Q3 25
$616.4M
$5.5M
Q2 25
$521.2M
$4.5M
Q1 25
$399.8M
$6.1M
Q4 24
$291.1M
$4.3M
Q3 24
$396.3M
$10.3M
Q2 24
$535.1M
$99.6M
Total Debt
ALKS
ALKS
HESM
HESM
Q1 26
Q4 25
$3.8B
Q3 25
Q2 25
Q1 25
Q4 24
$3.5B
Q3 24
Q2 24
Stockholders' Equity
ALKS
ALKS
HESM
HESM
Q1 26
Q4 25
$1.8B
Q3 25
$1.7B
Q2 25
$1.6B
Q1 25
$1.5B
Q4 24
$1.5B
Q3 24
$1.3B
Q2 24
$1.3B
Total Assets
ALKS
ALKS
HESM
HESM
Q1 26
Q4 25
$2.5B
$4.4B
Q3 25
$2.3B
$4.4B
Q2 25
$2.3B
$4.4B
Q1 25
$2.1B
$4.3B
Q4 24
$2.1B
$4.2B
Q3 24
$2.2B
$4.1B
Q2 24
$2.2B
$4.1B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ALKS
ALKS
HESM
HESM
Operating Cash FlowLast quarter
$170.1M
$253.3M
Free Cash FlowOCF − Capex
$170.0M
FCF MarginFCF / Revenue
44.2%
Capex IntensityCapex / Revenue
0.0%
51.4%
Cash ConversionOCF / Net Profit
3.45×
1.61×
TTM Free Cash FlowTrailing 4 quarters
$480.3M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ALKS
ALKS
HESM
HESM
Q1 26
$253.3M
Q4 25
$170.1M
$245.6M
Q3 25
$101.7M
$258.9M
Q2 25
$150.2M
$276.9M
Q1 25
$98.8M
$202.4M
Q4 24
$190.4M
$258.5M
Q3 24
$81.6M
$224.9M
Q2 24
$146.0M
$271.6M
Free Cash Flow
ALKS
ALKS
HESM
HESM
Q1 26
Q4 25
$170.0M
$178.9M
Q3 25
$84.4M
$178.9M
Q2 25
$137.2M
$213.5M
Q1 25
$88.7M
$156.9M
Q4 24
$180.6M
$163.4M
Q3 24
$73.3M
$132.6M
Q2 24
$138.9M
$207.7M
FCF Margin
ALKS
ALKS
HESM
HESM
Q1 26
Q4 25
44.2%
44.3%
Q3 25
21.4%
42.5%
Q2 25
35.1%
51.5%
Q1 25
28.9%
41.1%
Q4 24
42.0%
41.3%
Q3 24
19.4%
35.0%
Q2 24
34.8%
56.8%
Capex Intensity
ALKS
ALKS
HESM
HESM
Q1 26
51.4%
Q4 25
0.0%
16.5%
Q3 25
4.4%
19.0%
Q2 25
3.3%
15.3%
Q1 25
3.3%
11.9%
Q4 24
2.3%
24.0%
Q3 24
2.2%
24.4%
Q2 24
1.8%
17.5%
Cash Conversion
ALKS
ALKS
HESM
HESM
Q1 26
1.61×
Q4 25
3.45×
2.63×
Q3 25
1.23×
2.65×
Q2 25
1.72×
3.07×
Q1 25
4.40×
2.83×
Q4 24
1.30×
3.67×
Q3 24
0.88×
3.84×
Q2 24
1.60×
5.49×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

ALKS
ALKS

Vivitrol$124.1M32%
Aristada And Aristada Initio$97.2M25%
LYBALVI$94.1M24%
Royalty$65.7M17%
Manufacturing Revenue$3.3M1%

HESM
HESM

Affiliate services$197.9M97%
Third-party services$6.2M3%

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