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Side-by-side financial comparison of ALNYLAM PHARMACEUTICALS, INC. (ALNY) and CIMPRESS plc (CMPR). Click either name above to swap in a different company.

ALNYLAM PHARMACEUTICALS, INC. is the larger business by last-quarter revenue ($1.2B vs $1.0B, roughly 1.1× CIMPRESS plc). ALNYLAM PHARMACEUTICALS, INC. runs the higher net margin — 17.6% vs 4.7%, a 12.9% gap on every dollar of revenue. On growth, ALNYLAM PHARMACEUTICALS, INC. posted the faster year-over-year revenue change (96.4% vs 11.0%).

Alnylam Pharmaceuticals, Inc. is an American biopharmaceutical company focused on the discovery, development and commercialization of RNA interference (RNAi) therapeutics for genetically defined diseases. The company was founded in 2002 and is headquartered in Cambridge, Massachusetts. In 2016, Forbes included the company on its "100 Most Innovative Growth Companies" list.

Cimpress plc is an American Irish-domiciled multinational technology company that invests in and operates a wide variety of businesses that use mass customization to configure and produce small quantities of individually customized goods. Those products are sold to small businesses, graphic designers and consumers through a number of customer-facing brands that Cimpress operates.

ALNY vs CMPR — Head-to-Head

Bigger by revenue
ALNY
ALNY
1.1× larger
ALNY
$1.2B
$1.0B
CMPR
Growing faster (revenue YoY)
ALNY
ALNY
+85.5% gap
ALNY
96.4%
11.0%
CMPR
Higher net margin
ALNY
ALNY
12.9% more per $
ALNY
17.6%
4.7%
CMPR

Income Statement — Q1 FY2026 vs Q2 FY2026

Metric
ALNY
ALNY
CMPR
CMPR
Revenue
$1.2B
$1.0B
Net Profit
$206.0M
$49.3M
Gross Margin
82.2%
46.8%
Operating Margin
23.0%
8.5%
Net Margin
17.6%
4.7%
Revenue YoY
96.4%
11.0%
Net Profit YoY
-19.2%
EPS (diluted)
$1.51
$1.95

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ALNY
ALNY
CMPR
CMPR
Q1 26
$1.2B
Q4 25
$1.1B
$1.0B
Q3 25
$1.2B
$863.3M
Q2 25
$773.7M
Q1 25
$594.2M
Q4 24
$593.2M
Q3 24
$500.9M
Q2 24
$659.8M
Net Profit
ALNY
ALNY
CMPR
CMPR
Q1 26
$206.0M
Q4 25
$186.4M
$49.3M
Q3 25
$251.1M
$7.6M
Q2 25
$-66.3M
Q1 25
$-57.5M
Q4 24
$-83.8M
Q3 24
$-111.6M
Q2 24
$-16.9M
Gross Margin
ALNY
ALNY
CMPR
CMPR
Q1 26
82.2%
Q4 25
75.6%
46.8%
Q3 25
84.2%
46.7%
Q2 25
81.6%
Q1 25
88.2%
Q4 24
82.7%
Q3 24
83.6%
Q2 24
89.8%
Operating Margin
ALNY
ALNY
CMPR
CMPR
Q1 26
23.0%
Q4 25
12.0%
8.5%
Q3 25
29.5%
5.7%
Q2 25
-2.1%
Q1 25
3.0%
Q4 24
-17.7%
Q3 24
-15.4%
Q2 24
7.4%
Net Margin
ALNY
ALNY
CMPR
CMPR
Q1 26
17.6%
Q4 25
17.0%
4.7%
Q3 25
20.1%
0.9%
Q2 25
-8.6%
Q1 25
-9.7%
Q4 24
-14.1%
Q3 24
-22.3%
Q2 24
-2.6%
EPS (diluted)
ALNY
ALNY
CMPR
CMPR
Q1 26
$1.51
Q4 25
$1.44
$1.95
Q3 25
$1.84
$0.30
Q2 25
$-0.51
Q1 25
$-0.44
Q4 24
$-0.66
Q3 24
$-0.87
Q2 24
$-0.13

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ALNY
ALNY
CMPR
CMPR
Cash + ST InvestmentsLiquidity on hand
$1.7B
$258.0M
Total DebtLower is stronger
Stockholders' EquityBook value
$1.1B
$-530.7M
Total Assets
$5.1B
$2.1B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ALNY
ALNY
CMPR
CMPR
Q1 26
$1.7B
Q4 25
$1.7B
$258.0M
Q3 25
$1.5B
$200.5M
Q2 25
$1.1B
Q1 25
$1.0B
Q4 24
$966.4M
Q3 24
$1.1B
Q2 24
$968.5M
Stockholders' Equity
ALNY
ALNY
CMPR
CMPR
Q1 26
$1.1B
Q4 25
$789.2M
$-530.7M
Q3 25
$233.9M
$-571.3M
Q2 25
$250.6M
Q1 25
$115.4M
Q4 24
$67.1M
Q3 24
$32.4M
Q2 24
$-3.1M
Total Assets
ALNY
ALNY
CMPR
CMPR
Q1 26
$5.1B
Q4 25
$5.0B
$2.1B
Q3 25
$4.9B
$2.0B
Q2 25
$4.6B
Q1 25
$4.2B
Q4 24
$4.2B
Q3 24
$4.2B
Q2 24
$4.0B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ALNY
ALNY
CMPR
CMPR
Operating Cash FlowLast quarter
$164.7M
Free Cash FlowOCF − Capex
$139.5M
FCF MarginFCF / Revenue
13.4%
Capex IntensityCapex / Revenue
2.4%
Cash ConversionOCF / Net Profit
3.34×
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ALNY
ALNY
CMPR
CMPR
Q1 26
Q4 25
$163.6M
$164.7M
Q3 25
$325.1M
$25.1M
Q2 25
$153.7M
Q1 25
$-118.3M
Q4 24
$-94.7M
Q3 24
$43.7M
Q2 24
$124.2M
Free Cash Flow
ALNY
ALNY
CMPR
CMPR
Q1 26
Q4 25
$140.3M
$139.5M
Q3 25
$313.0M
$-1.3M
Q2 25
$139.4M
Q1 25
$-127.3M
Q4 24
$-103.8M
Q3 24
$39.5M
Q2 24
$116.1M
FCF Margin
ALNY
ALNY
CMPR
CMPR
Q1 26
Q4 25
12.8%
13.4%
Q3 25
25.1%
-0.1%
Q2 25
18.0%
Q1 25
-21.4%
Q4 24
-17.5%
Q3 24
7.9%
Q2 24
17.6%
Capex Intensity
ALNY
ALNY
CMPR
CMPR
Q1 26
Q4 25
2.1%
2.4%
Q3 25
1.0%
3.1%
Q2 25
1.8%
Q1 25
1.5%
Q4 24
1.5%
Q3 24
0.8%
Q2 24
1.2%
Cash Conversion
ALNY
ALNY
CMPR
CMPR
Q1 26
Q4 25
0.88×
3.34×
Q3 25
1.29×
3.28×
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

ALNY
ALNY

AMVUTTRA$889.9M76%
GIVLAARI$74.4M6%
OXLUMO$51.3M4%
Royalty revenue$49.0M4%
Regeneron Pharmaceuticals$46.3M4%
Roche$35.6M3%
ONPATTRO$20.5M2%

CMPR
CMPR

Vista$532.8M51%
Print Brothers$219.9M21%
National Pen$150.9M14%
The Print Group$115.2M11%
All Other Businesses$67.2M6%

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