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Side-by-side financial comparison of ALNYLAM PHARMACEUTICALS, INC. (ALNY) and KeyCorp (KEY). Click either name above to swap in a different company.

KeyCorp is the larger business by last-quarter revenue ($1.9B vs $1.2B, roughly 1.7× ALNYLAM PHARMACEUTICALS, INC.). KeyCorp runs the higher net margin — 26.8% vs 17.6%, a 9.2% gap on every dollar of revenue. On growth, ALNYLAM PHARMACEUTICALS, INC. posted the faster year-over-year revenue change (96.4% vs 10.2%). Over the past eight quarters, ALNYLAM PHARMACEUTICALS, INC.'s revenue compounded faster (33.0% CAGR vs 12.9%).

Alnylam Pharmaceuticals, Inc. is an American biopharmaceutical company focused on the discovery, development and commercialization of RNA interference (RNAi) therapeutics for genetically defined diseases. The company was founded in 2002 and is headquartered in Cambridge, Massachusetts. In 2016, Forbes included the company on its "100 Most Innovative Growth Companies" list.

Key is a Japanese visual novel studio known for making dramatic and plot-oriented titles. It was formed on July 21, 1998, as a brand under the publisher Visual Arts, and is located in Kita, Osaka.

ALNY vs KEY — Head-to-Head

Bigger by revenue
KEY
KEY
1.7× larger
KEY
$1.9B
$1.2B
ALNY
Growing faster (revenue YoY)
ALNY
ALNY
+86.3% gap
ALNY
96.4%
10.2%
KEY
Higher net margin
KEY
KEY
9.2% more per $
KEY
26.8%
17.6%
ALNY
Faster 2-yr revenue CAGR
ALNY
ALNY
Annualised
ALNY
33.0%
12.9%
KEY

Income Statement — Q1 FY2026 vs Q1 FY2026

Metric
ALNY
ALNY
KEY
KEY
Revenue
$1.2B
$1.9B
Net Profit
$206.0M
$522.0M
Gross Margin
82.2%
Operating Margin
23.0%
Net Margin
17.6%
26.8%
Revenue YoY
96.4%
10.2%
Net Profit YoY
28.9%
EPS (diluted)
$1.51
$0.44

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ALNY
ALNY
KEY
KEY
Q1 26
$1.2B
$1.9B
Q4 25
$1.1B
$2.0B
Q3 25
$1.2B
$1.9B
Q2 25
$773.7M
$1.8B
Q1 25
$594.2M
$1.8B
Q4 24
$593.2M
$865.0M
Q3 24
$500.9M
$695.0M
Q2 24
$659.8M
$1.5B
Net Profit
ALNY
ALNY
KEY
KEY
Q1 26
$206.0M
$522.0M
Q4 25
$186.4M
$510.0M
Q3 25
$251.1M
$489.0M
Q2 25
$-66.3M
$425.0M
Q1 25
$-57.5M
$405.0M
Q4 24
$-83.8M
$-244.0M
Q3 24
$-111.6M
$-410.0M
Q2 24
$-16.9M
$274.0M
Gross Margin
ALNY
ALNY
KEY
KEY
Q1 26
82.2%
Q4 25
75.6%
Q3 25
84.2%
Q2 25
81.6%
Q1 25
88.2%
Q4 24
82.7%
Q3 24
83.6%
Q2 24
89.8%
Operating Margin
ALNY
ALNY
KEY
KEY
Q1 26
23.0%
Q4 25
12.0%
32.3%
Q3 25
29.5%
31.8%
Q2 25
-2.1%
29.3%
Q1 25
3.0%
29.0%
Q4 24
-17.7%
-92.6%
Q3 24
-15.4%
-72.8%
Q2 24
7.4%
22.0%
Net Margin
ALNY
ALNY
KEY
KEY
Q1 26
17.6%
26.8%
Q4 25
17.0%
25.4%
Q3 25
20.1%
25.8%
Q2 25
-8.6%
23.1%
Q1 25
-9.7%
22.8%
Q4 24
-14.1%
-54.7%
Q3 24
-22.3%
-59.0%
Q2 24
-2.6%
18.0%
EPS (diluted)
ALNY
ALNY
KEY
KEY
Q1 26
$1.51
$0.44
Q4 25
$1.44
$0.43
Q3 25
$1.84
$0.41
Q2 25
$-0.51
$0.35
Q1 25
$-0.44
$0.33
Q4 24
$-0.66
$-0.30
Q3 24
$-0.87
$-0.47
Q2 24
$-0.13
$0.25

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ALNY
ALNY
KEY
KEY
Cash + ST InvestmentsLiquidity on hand
$1.7B
$11.8B
Total DebtLower is stronger
$10.9B
Stockholders' EquityBook value
$1.1B
$20.0B
Total Assets
$5.1B
$188.7B
Debt / EquityLower = less leverage
0.54×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ALNY
ALNY
KEY
KEY
Q1 26
$1.7B
$11.8B
Q4 25
$1.7B
$10.2B
Q3 25
$1.5B
$13.3B
Q2 25
$1.1B
$11.6B
Q1 25
$1.0B
$15.3B
Q4 24
$966.4M
$17.5B
Q3 24
$1.1B
$22.8B
Q2 24
$968.5M
$15.5B
Total Debt
ALNY
ALNY
KEY
KEY
Q1 26
$10.9B
Q4 25
$9.9B
Q3 25
$10.9B
Q2 25
$12.1B
Q1 25
$12.4B
Q4 24
$12.1B
Q3 24
$15.7B
Q2 24
$16.9B
Stockholders' Equity
ALNY
ALNY
KEY
KEY
Q1 26
$1.1B
$20.0B
Q4 25
$789.2M
$20.4B
Q3 25
$233.9M
$20.1B
Q2 25
$250.6M
$19.5B
Q1 25
$115.4M
$19.0B
Q4 24
$67.1M
$18.2B
Q3 24
$32.4M
$16.9B
Q2 24
$-3.1M
$14.8B
Total Assets
ALNY
ALNY
KEY
KEY
Q1 26
$5.1B
$188.7B
Q4 25
$5.0B
$184.4B
Q3 25
$4.9B
$187.4B
Q2 25
$4.6B
$185.5B
Q1 25
$4.2B
$188.7B
Q4 24
$4.2B
$187.2B
Q3 24
$4.2B
$189.8B
Q2 24
$4.0B
$187.4B
Debt / Equity
ALNY
ALNY
KEY
KEY
Q1 26
0.54×
Q4 25
0.49×
Q3 25
0.54×
Q2 25
0.62×
Q1 25
0.65×
Q4 24
0.67×
Q3 24
0.93×
Q2 24
1.14×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

ALNY
ALNY

AMVUTTRA$889.9M76%
GIVLAARI$74.4M6%
OXLUMO$51.3M4%
Royalty revenue$49.0M4%
Regeneron Pharmaceuticals$46.3M4%
Roche$35.6M3%
ONPATTRO$20.5M2%

KEY
KEY

Net Interest Income$1.2B63%
Noninterest Income$723.0M37%

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