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Side-by-side financial comparison of Altimmune, Inc. (ALT) and SOPHiA GENETICS SA (SOPH). Click either name above to swap in a different company.

SOPHiA GENETICS SA is the larger business by last-quarter revenue ($47.4K vs $26.0K, roughly 1.8× Altimmune, Inc.). SOPHiA GENETICS SA produced more free cash flow last quarter ($-33.6K vs $-67.5M). Over the past eight quarters, Altimmune, Inc.'s revenue compounded faster (128.0% CAGR vs 45.1%).

Altimmune, Inc. is a clinical-stage biopharmaceutical company focused on developing innovative immunotherapies, vaccines, and peptide-based therapies. Its pipeline covers infectious disease prevention, liver disease treatments, and metabolic disorder therapies, serving global biopharmaceutical and healthcare markets while advancing candidates through clinical trials.

Sophia Genetics SA is a Swiss-founded data-driven medicine software company with headquarters in Rolle, Switzerland and Boston, Massachusetts, as well as offices in France. It provides genomic and radiomic, and multimodal analysis for hospitals, laboratories, and biopharma institutions.

ALT vs SOPH — Head-to-Head

Bigger by revenue
SOPH
SOPH
1.8× larger
SOPH
$47.4K
$26.0K
ALT
More free cash flow
SOPH
SOPH
$67.5M more FCF
SOPH
$-33.6K
$-67.5M
ALT
Faster 2-yr revenue CAGR
ALT
ALT
Annualised
ALT
128.0%
45.1%
SOPH

Income Statement — Q4 FY2025 vs Q3 FY2025

Metric
ALT
ALT
SOPH
SOPH
Revenue
$26.0K
$47.4K
Net Profit
Gross Margin
67.1%
Operating Margin
-103.5%
Net Margin
Revenue YoY
420.0%
Net Profit YoY
-18.0%
EPS (diluted)

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ALT
ALT
SOPH
SOPH
Q4 25
$26.0K
Q3 25
$5.0K
$47.4K
Q2 25
$5.0K
$15.8K
Q1 25
$5.0K
$15.8K
Q4 24
$5.0K
Q3 24
$5.0K
$45.3K
Q2 24
$5.0K
$29.0K
Q1 24
$5.0K
$14.0K
Net Profit
ALT
ALT
SOPH
SOPH
Q4 25
Q3 25
$-19.0M
Q2 25
$-22.1M
$-22.4M
Q1 25
$-19.6M
Q4 24
Q3 24
$-22.8M
Q2 24
$-24.6M
$-15.2M
Q1 24
$-24.4M
Gross Margin
ALT
ALT
SOPH
SOPH
Q4 25
Q3 25
67.1%
Q2 25
Q1 25
65.9%
Q4 24
Q3 24
68.4%
Q2 24
Q1 24
69.4%
Operating Margin
ALT
ALT
SOPH
SOPH
Q4 25
Q3 25
-417180.0%
-103.5%
Q2 25
-458440.0%
-116978.7%
Q1 25
-436300.0%
-118.9%
Q4 24
Q3 24
-495340.0%
-123.3%
Q2 24
-534900.0%
-51705.7%
Q1 24
-535880.0%
-138.1%
Net Margin
ALT
ALT
SOPH
SOPH
Q4 25
Q3 25
-380280.0%
Q2 25
-442920.0%
-141789.0%
Q1 25
-391500.0%
Q4 24
Q3 24
-456900.0%
Q2 24
-492800.0%
-52353.5%
Q1 24
-487880.0%
EPS (diluted)
ALT
ALT
SOPH
SOPH
Q4 25
Q3 25
$-0.21
Q2 25
$-0.27
$-0.33
Q1 25
$-0.26
Q4 24
Q3 24
$-0.32
Q2 24
$-0.35
$-0.23
Q1 24
$-0.34

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ALT
ALT
SOPH
SOPH
Cash + ST InvestmentsLiquidity on hand
$273.5M
$80.2K
Total DebtLower is stronger
$34.3M
Stockholders' EquityBook value
$224.9M
$96.5K
Total Assets
$279.9M
$155.3K
Debt / EquityLower = less leverage
0.15×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ALT
ALT
SOPH
SOPH
Q4 25
$273.5M
Q3 25
$210.8M
$80.2K
Q2 25
$183.1M
$94.8M
Q1 25
$149.8M
$80.2K
Q4 24
$131.9M
Q3 24
$139.4M
$123.3K
Q2 24
$164.9M
$105.4M
Q1 24
$182.0M
$123.3K
Total Debt
ALT
ALT
SOPH
SOPH
Q4 25
$34.3M
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
Stockholders' Equity
ALT
ALT
SOPH
SOPH
Q4 25
$224.9M
Q3 25
$185.6M
$96.5K
Q2 25
$161.4M
$76.7M
Q1 25
$142.2M
$85.6M
Q4 24
$123.5M
Q3 24
$133.4M
$151.4K
Q2 24
$152.5M
$121.4M
Q1 24
$172.9M
$132.2M
Total Assets
ALT
ALT
SOPH
SOPH
Q4 25
$279.9M
Q3 25
$218.4M
$155.3K
Q2 25
$190.3M
$177.6M
Q1 25
$157.3M
$155.3K
Q4 24
$139.3M
Q3 24
$147.9M
$206.2K
Q2 24
$173.3M
$181.1M
Q1 24
$188.4M
$206.2K
Debt / Equity
ALT
ALT
SOPH
SOPH
Q4 25
0.15×
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ALT
ALT
SOPH
SOPH
Operating Cash FlowLast quarter
$-67.5M
$-33.5K
Free Cash FlowOCF − Capex
$-67.5M
$-33.6K
FCF MarginFCF / Revenue
-259792.3%
-70.9%
Capex IntensityCapex / Revenue
42.3%
0.4%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ALT
ALT
SOPH
SOPH
Q4 25
$-67.5M
Q3 25
$-11.9M
$-33.5K
Q2 25
$-19.4M
Q1 25
$-16.8M
$-14.6K
Q4 24
$-79.8M
Q3 24
$-27.1M
$-39.9K
Q2 24
$-18.1M
$-26.7K
Q1 24
$-16.4M
$-15.7K
Free Cash Flow
ALT
ALT
SOPH
SOPH
Q4 25
$-67.5M
Q3 25
$-33.6K
Q2 25
Q1 25
Q4 24
Q3 24
$-41.2K
Q2 24
$-27.9K
Q1 24
$-16.2K
FCF Margin
ALT
ALT
SOPH
SOPH
Q4 25
-259792.3%
Q3 25
-70.9%
Q2 25
Q1 25
Q4 24
Q3 24
-91.0%
Q2 24
-96.2%
Q1 24
-115.8%
Capex Intensity
ALT
ALT
SOPH
SOPH
Q4 25
42.3%
Q3 25
0.0%
0.4%
Q2 25
Q1 25
Q4 24
Q3 24
3.0%
Q2 24
4.3%
Q1 24
3.6%

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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