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Side-by-side financial comparison of Amgen (AMGN) and Moderna (MRNA). Click either name above to swap in a different company.
Amgen is the larger business by last-quarter revenue ($9.9B vs $1.0B, roughly 9.7× Moderna). Amgen runs the higher net margin — 13.5% vs -19.7%, a 33.2% gap on every dollar of revenue. On growth, Amgen posted the faster year-over-year revenue change (8.6% vs -45.4%). Amgen produced more free cash flow last quarter ($961.0M vs $-880.0M). Over the past eight quarters, Amgen's revenue compounded faster (15.1% CAGR vs -45.0%).
Amgen Inc. is an American multinational biopharmaceutical company headquartered in Thousand Oaks, California. The company is ranked 18th on the list of largest biomedical companies by revenue. The name "AMGen" is a portmanteau of the company's original name, Applied Molecular Genetics.
Moderna, Inc. is an American pharmaceutical and biotechnology company based in Cambridge, Massachusetts, that focuses on RNA therapeutics, primarily mRNA vaccines. These vaccines use a copy of a molecule called messenger RNA (mRNA) to carry instructions for proteins to produce an immune response. The company's name is derived from the terms "modified", "RNA", and "modern".
AMGN vs MRNA — Head-to-Head
Income Statement — Q4 FY2025 vs Q3 FY2025
| Metric | | |
|---|---|---|
| Revenue | $9.9B | $1.0B |
| Net Profit | $1.3B | $-200.0M |
| Gross Margin | 69.8% | 79.6% |
| Operating Margin | 27.6% | -25.6% |
| Net Margin | 13.5% | -19.7% |
| Revenue YoY | 8.6% | -45.4% |
| Net Profit YoY | 112.6% | -1638.5% |
| EPS (diluted) | $2.45 | $-0.51 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $9.9B | — | ||
| Q3 25 | $9.6B | $1.0B | ||
| Q2 25 | $9.2B | — | ||
| Q1 25 | $8.1B | — | ||
| Q4 24 | $9.1B | $966.0M | ||
| Q3 24 | $8.5B | $1.9B | ||
| Q2 24 | $8.4B | — | ||
| Q1 24 | $7.4B | — |
| Q4 25 | $1.3B | — | ||
| Q3 25 | $3.2B | $-200.0M | ||
| Q2 25 | $1.4B | — | ||
| Q1 25 | $1.7B | — | ||
| Q4 24 | $627.0M | $-1.1B | ||
| Q3 24 | $2.8B | $13.0M | ||
| Q2 24 | $746.0M | — | ||
| Q1 24 | $-113.0M | — |
| Q4 25 | 69.8% | — | ||
| Q3 25 | 67.8% | 79.6% | ||
| Q2 25 | 67.2% | — | ||
| Q1 25 | 63.6% | — | ||
| Q4 24 | 65.7% | 23.5% | ||
| Q3 24 | 61.1% | 72.4% | ||
| Q2 24 | 61.4% | — | ||
| Q1 24 | 57.0% | — |
| Q4 25 | 27.6% | — | ||
| Q3 25 | 26.4% | -25.6% | ||
| Q2 25 | 28.9% | — | ||
| Q1 25 | 14.5% | — | ||
| Q4 24 | 25.4% | -129.0% | ||
| Q3 24 | 24.1% | -3.8% | ||
| Q2 24 | 22.8% | — | ||
| Q1 24 | 13.3% | — |
| Q4 25 | 13.5% | — | ||
| Q3 25 | 33.7% | -19.7% | ||
| Q2 25 | 15.6% | — | ||
| Q1 25 | 21.2% | — | ||
| Q4 24 | 6.9% | -115.9% | ||
| Q3 24 | 33.3% | 0.7% | ||
| Q2 24 | 8.9% | — | ||
| Q1 24 | -1.5% | — |
| Q4 25 | $2.45 | — | ||
| Q3 25 | $5.93 | $-0.51 | ||
| Q2 25 | $2.65 | — | ||
| Q1 25 | $3.20 | — | ||
| Q4 24 | $1.17 | $-2.91 | ||
| Q3 24 | $5.22 | $0.03 | ||
| Q2 24 | $1.38 | — | ||
| Q1 24 | $-0.21 | — |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $9.1B | $1.1B |
| Total DebtLower is stronger | $54.6B | — |
| Stockholders' EquityBook value | $8.7B | $9.3B |
| Total Assets | $90.6B | $12.1B |
| Debt / EquityLower = less leverage | 6.31× | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $9.1B | — | ||
| Q3 25 | $9.4B | $1.1B | ||
| Q2 25 | $8.0B | — | ||
| Q1 25 | $8.8B | — | ||
| Q4 24 | $12.0B | $1.9B | ||
| Q3 24 | $9.0B | $1.6B | ||
| Q2 24 | $9.3B | — | ||
| Q1 24 | $9.7B | — |
| Q4 25 | $54.6B | — | ||
| Q3 25 | $54.6B | — | ||
| Q2 25 | $56.2B | — | ||
| Q1 25 | $57.4B | — | ||
| Q4 24 | $60.1B | — | ||
| Q3 24 | $60.4B | — | ||
| Q2 24 | $62.6B | — | ||
| Q1 24 | $64.0B | — |
| Q4 25 | $8.7B | — | ||
| Q3 25 | $9.6B | $9.3B | ||
| Q2 25 | $7.4B | — | ||
| Q1 25 | $6.2B | — | ||
| Q4 24 | $5.9B | $10.9B | ||
| Q3 24 | $7.5B | $11.9B | ||
| Q2 24 | $5.9B | — | ||
| Q1 24 | $5.0B | — |
| Q4 25 | $90.6B | — | ||
| Q3 25 | $90.1B | $12.1B | ||
| Q2 25 | $87.9B | — | ||
| Q1 25 | $89.4B | — | ||
| Q4 24 | $91.8B | $14.1B | ||
| Q3 24 | $90.9B | $15.8B | ||
| Q2 24 | $90.9B | — | ||
| Q1 24 | $93.0B | — |
| Q4 25 | 6.31× | — | ||
| Q3 25 | 5.67× | — | ||
| Q2 25 | 7.57× | — | ||
| Q1 25 | 9.24× | — | ||
| Q4 24 | 10.23× | — | ||
| Q3 24 | 8.02× | — | ||
| Q2 24 | 10.57× | — | ||
| Q1 24 | 12.75× | — |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $1.6B | $-847.0M |
| Free Cash FlowOCF − Capex | $961.0M | $-880.0M |
| FCF MarginFCF / Revenue | 9.7% | -86.6% |
| Capex IntensityCapex / Revenue | 6.5% | 3.2% |
| Cash ConversionOCF / Net Profit | 1.20× | — |
| TTM Free Cash FlowTrailing 4 quarters | $8.1B | $-1.9B |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $1.6B | — | ||
| Q3 25 | $4.7B | $-847.0M | ||
| Q2 25 | $2.3B | — | ||
| Q1 25 | $1.4B | — | ||
| Q4 24 | $4.8B | $825.0M | ||
| Q3 24 | $3.6B | $-1.6B | ||
| Q2 24 | $2.5B | — | ||
| Q1 24 | $689.0M | — |
| Q4 25 | $961.0M | — | ||
| Q3 25 | $4.2B | $-880.0M | ||
| Q2 25 | $1.9B | — | ||
| Q1 25 | $980.0M | — | ||
| Q4 24 | $4.4B | $303.0M | ||
| Q3 24 | $3.3B | $-1.7B | ||
| Q2 24 | $2.2B | — | ||
| Q1 24 | $459.0M | — |
| Q4 25 | 9.7% | — | ||
| Q3 25 | 44.4% | -86.6% | ||
| Q2 25 | 20.8% | — | ||
| Q1 25 | 12.0% | — | ||
| Q4 24 | 48.4% | 31.4% | ||
| Q3 24 | 39.0% | -92.2% | ||
| Q2 24 | 26.5% | — | ||
| Q1 24 | 6.2% | — |
| Q4 25 | 6.5% | — | ||
| Q3 25 | 4.6% | 3.2% | ||
| Q2 25 | 4.0% | — | ||
| Q1 25 | 5.0% | — | ||
| Q4 24 | 4.1% | 54.0% | ||
| Q3 24 | 3.0% | 8.1% | ||
| Q2 24 | 2.8% | — | ||
| Q1 24 | 3.1% | — |
| Q4 25 | 1.20× | — | ||
| Q3 25 | 1.46× | — | ||
| Q2 25 | 1.59× | — | ||
| Q1 25 | 0.80× | — | ||
| Q4 24 | 7.61× | — | ||
| Q3 24 | 1.26× | -120.46× | ||
| Q2 24 | 3.30× | — | ||
| Q1 24 | — | — |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
AMGN
| Products | $9.4B | 95% |
| Xgeva | $291.0M | 3% |
| Vectibix | $163.0M | 2% |
| Aranesp | $115.0M | 1% |
MRNA
| COVID19 | $971.0M | 96% |
| Other Revenue | $20.0M | 2% |
| Grant | $14.0M | 1% |
| Collaboration Arrangement Including Arrangements With Affiliate | $7.0M | 1% |
| License And Royalty | $2.0M | 0% |
