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Side-by-side financial comparison of AMERISAFE INC (AMSF) and Twist Bioscience Corp (TWST). Click either name above to swap in a different company.

Twist Bioscience Corp is the larger business by last-quarter revenue ($103.7M vs $80.1M, roughly 1.3× AMERISAFE INC). AMERISAFE INC runs the higher net margin — 10.2% vs -29.4%, a 39.6% gap on every dollar of revenue. On growth, Twist Bioscience Corp posted the faster year-over-year revenue change (16.9% vs 10.3%).

AMERISAFE Inc. is a specialty insurance provider that focuses exclusively on workers' compensation coverage for small and mid-sized businesses in high-hazard industries including construction, logging, trucking, and manufacturing. It operates across 49 U.S. states, offering tailored insurance policies paired with targeted risk management support for clients.

Twist Bioscience is a public biotechnology company based in South San Francisco that manufactures synthetic DNA and DNA products for customers in a wide range of industries. Twist was founded in 2013 by Emily Leproust, Bill Banyai, and Bill Peck.

AMSF vs TWST — Head-to-Head

Bigger by revenue
TWST
TWST
1.3× larger
TWST
$103.7M
$80.1M
AMSF
Growing faster (revenue YoY)
TWST
TWST
+6.6% gap
TWST
16.9%
10.3%
AMSF
Higher net margin
AMSF
AMSF
39.6% more per $
AMSF
10.2%
-29.4%
TWST

Income Statement — Q1 FY2026 vs Q1 FY2026

Metric
AMSF
AMSF
TWST
TWST
Revenue
$80.1M
$103.7M
Net Profit
$8.1M
$-30.5M
Gross Margin
52.0%
Operating Margin
-31.7%
Net Margin
10.2%
-29.4%
Revenue YoY
10.3%
16.9%
Net Profit YoY
-9.0%
3.4%
EPS (diluted)
$0.43
$-0.50

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
AMSF
AMSF
TWST
TWST
Q1 26
$80.1M
Q4 25
$81.6M
$103.7M
Q3 25
$82.0M
Q2 25
$81.1M
Q1 25
$72.6M
Q4 24
$74.0M
Q3 24
$78.7M
Q2 24
$75.8M
Net Profit
AMSF
AMSF
TWST
TWST
Q1 26
$8.1M
Q4 25
$10.4M
$-30.5M
Q3 25
$13.8M
Q2 25
$14.0M
Q1 25
$8.9M
Q4 24
$13.2M
Q3 24
$14.3M
Q2 24
$11.0M
Gross Margin
AMSF
AMSF
TWST
TWST
Q1 26
Q4 25
52.0%
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Operating Margin
AMSF
AMSF
TWST
TWST
Q1 26
Q4 25
15.6%
-31.7%
Q3 25
21.3%
Q2 25
21.5%
Q1 25
15.5%
Q4 24
22.7%
Q3 24
22.6%
Q2 24
18.1%
Net Margin
AMSF
AMSF
TWST
TWST
Q1 26
10.2%
Q4 25
12.8%
-29.4%
Q3 25
16.9%
Q2 25
17.2%
Q1 25
12.3%
Q4 24
17.8%
Q3 24
18.2%
Q2 24
14.5%
EPS (diluted)
AMSF
AMSF
TWST
TWST
Q1 26
$0.43
Q4 25
$0.55
$-0.50
Q3 25
$0.72
Q2 25
$0.73
Q1 25
$0.47
Q4 24
$0.69
Q3 24
$0.75
Q2 24
$0.57

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
AMSF
AMSF
TWST
TWST
Cash + ST InvestmentsLiquidity on hand
$34.2M
$197.9M
Total DebtLower is stronger
Stockholders' EquityBook value
$246.6M
$456.1M
Total Assets
$638.1M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
AMSF
AMSF
TWST
TWST
Q1 26
$34.2M
Q4 25
$61.9M
$197.9M
Q3 25
$54.7M
Q2 25
$48.5M
Q1 25
$44.8M
Q4 24
$44.1M
Q3 24
$63.7M
Q2 24
$30.6M
Stockholders' Equity
AMSF
AMSF
TWST
TWST
Q1 26
$246.6M
Q4 25
$251.6M
$456.1M
Q3 25
$274.8M
Q2 25
$265.6M
Q1 25
$260.8M
Q4 24
$257.3M
Q3 24
$314.4M
Q2 24
$301.0M
Total Assets
AMSF
AMSF
TWST
TWST
Q1 26
Q4 25
$1.1B
$638.1M
Q3 25
$1.2B
Q2 25
$1.2B
Q1 25
$1.2B
Q4 24
$1.2B
Q3 24
$1.3B
Q2 24
$1.2B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
AMSF
AMSF
TWST
TWST
Operating Cash FlowLast quarter
$-24.8M
Free Cash FlowOCF − Capex
$-34.8M
FCF MarginFCF / Revenue
-33.5%
Capex IntensityCapex / Revenue
9.6%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
AMSF
AMSF
TWST
TWST
Q1 26
Q4 25
$11.1M
$-24.8M
Q3 25
$10.7M
Q2 25
$-8.4M
Q1 25
$-1.8M
Q4 24
$24.2M
Q3 24
$8.4M
Q2 24
$-2.6M
Free Cash Flow
AMSF
AMSF
TWST
TWST
Q1 26
Q4 25
$8.9M
$-34.8M
Q3 25
$9.8M
Q2 25
$-9.5M
Q1 25
$-1.8M
Q4 24
$23.4M
Q3 24
$8.4M
Q2 24
$-2.6M
FCF Margin
AMSF
AMSF
TWST
TWST
Q1 26
Q4 25
10.9%
-33.5%
Q3 25
11.9%
Q2 25
-11.7%
Q1 25
-2.5%
Q4 24
31.5%
Q3 24
10.7%
Q2 24
-3.5%
Capex Intensity
AMSF
AMSF
TWST
TWST
Q1 26
Q4 25
2.6%
9.6%
Q3 25
1.1%
Q2 25
1.3%
Q1 25
0.0%
Q4 24
1.1%
Q3 24
0.0%
Q2 24
0.1%
Cash Conversion
AMSF
AMSF
TWST
TWST
Q1 26
Q4 25
1.06×
Q3 25
0.77×
Q2 25
-0.61×
Q1 25
-0.20×
Q4 24
1.83×
Q3 24
0.59×
Q2 24
-0.24×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

AMSF
AMSF

Segment breakdown not available.

TWST
TWST

Industrial Chemicals$37.2M36%
Diagnostics$35.3M34%
Food Or Agriculture$12.8M12%
Academic Research$12.2M12%
Health Care$6.1M6%

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