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Side-by-side financial comparison of Amesite Inc. (AMST) and Clene Inc. (CLNN). Click either name above to swap in a different company.

Amesite Inc. is the larger business by last-quarter revenue ($108.0K vs $77.0K, roughly 1.4× Clene Inc.). Amesite Inc. runs the higher net margin — -678.0% vs -11981.8%, a 11303.8% gap on every dollar of revenue. On growth, Amesite Inc. posted the faster year-over-year revenue change (746.8% vs -15.4%). Over the past eight quarters, Clene Inc.'s revenue compounded faster (2.7% CAGR vs -32.5%).

Amesite Inc is a US-based edtech firm that develops and delivers AI-powered cloud learning management systems and customized online learning solutions. Its core offerings cater to higher education institutions, corporate clients, and government organizations, enabling scalable, personalized upskilling, professional training, and academic course delivery across North America.

Clene Inc. is a clinical-stage biopharmaceutical company that develops novel neuroprotective therapeutics to treat neurodegenerative diseases including amyotrophic lateral sclerosis (ALS), multiple sclerosis, and Parkinson’s disease. It operates primarily in the U.S. market, focusing on advancing its small molecule candidate pipeline through clinical trials to address unmet medical needs.

AMST vs CLNN — Head-to-Head

Bigger by revenue
AMST
AMST
1.4× larger
AMST
$108.0K
$77.0K
CLNN
Growing faster (revenue YoY)
AMST
AMST
+762.2% gap
AMST
746.8%
-15.4%
CLNN
Higher net margin
AMST
AMST
11303.8% more per $
AMST
-678.0%
-11981.8%
CLNN
Faster 2-yr revenue CAGR
CLNN
CLNN
Annualised
CLNN
2.7%
-32.5%
AMST

Income Statement — Q2 FY2026 vs Q4 FY2025

Metric
AMST
AMST
CLNN
CLNN
Revenue
$108.0K
$77.0K
Net Profit
$-732.5K
$-9.2M
Gross Margin
70.1%
Operating Margin
-689.7%
-9733.8%
Net Margin
-678.0%
-11981.8%
Revenue YoY
746.8%
-15.4%
Net Profit YoY
34.7%
31.9%
EPS (diluted)
$-0.16

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
AMST
AMST
CLNN
CLNN
Q4 25
$108.0K
$77.0K
Q3 25
$94.3K
$15.0K
Q2 25
$55.8K
$27.0K
Q1 25
$81.0K
Q4 24
$91.0K
Q3 24
$87.0K
Q2 24
$91.0K
Q1 24
$73.0K
Net Profit
AMST
AMST
CLNN
CLNN
Q4 25
$-732.5K
$-9.2M
Q3 25
$-642.3K
$-8.8M
Q2 25
$-924.0K
$-7.4M
Q1 25
$-751.0K
Q4 24
$-13.5M
Q3 24
$-8.0M
Q2 24
$-6.8M
Q1 24
$-11.1M
Gross Margin
AMST
AMST
CLNN
CLNN
Q4 25
70.1%
Q3 25
Q2 25
Q1 25
75.3%
Q4 24
80.2%
Q3 24
79.3%
Q2 24
80.2%
Q1 24
78.1%
Operating Margin
AMST
AMST
CLNN
CLNN
Q4 25
-689.7%
-9733.8%
Q3 25
-702.2%
-37653.3%
Q2 25
-1538.2%
-21718.5%
Q1 25
-5032.1%
Q4 24
-9511.0%
Q3 24
-8982.8%
Q2 24
-8122.0%
Q1 24
-12646.6%
Net Margin
AMST
AMST
CLNN
CLNN
Q4 25
-678.0%
-11981.8%
Q3 25
-681.1%
-58513.3%
Q2 25
-1657.1%
-27477.8%
Q1 25
-927.2%
Q4 24
-14889.0%
Q3 24
-9179.3%
Q2 24
-7456.0%
Q1 24
-15178.1%
EPS (diluted)
AMST
AMST
CLNN
CLNN
Q4 25
$-0.16
Q3 25
$-0.14
Q2 25
$-0.13
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
AMST
AMST
CLNN
CLNN
Cash + ST InvestmentsLiquidity on hand
$1.2M
$5.2M
Total DebtLower is stronger
$17.8M
Stockholders' EquityBook value
$1.5M
$-17.6M
Total Assets
$2.0M
$18.1M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
AMST
AMST
CLNN
CLNN
Q4 25
$1.2M
$5.2M
Q3 25
$1.8M
$7.9M
Q2 25
$2.3M
$7.3M
Q1 25
$9.8M
Q4 24
$12.2M
Q3 24
$14.6M
Q2 24
$21.7M
Q1 24
$27.9M
Total Debt
AMST
AMST
CLNN
CLNN
Q4 25
$17.8M
Q3 25
$17.9M
Q2 25
$16.5M
Q1 25
$16.6M
Q4 24
Q3 24
Q2 24
Q1 24
Stockholders' Equity
AMST
AMST
CLNN
CLNN
Q4 25
$1.5M
$-17.6M
Q3 25
$2.2M
$-12.4M
Q2 25
$2.7M
$-8.6M
Q1 25
$-5.0M
Q4 24
$-8.9M
Q3 24
$-4.1M
Q2 24
$-504.0K
Q1 24
$4.3M
Total Assets
AMST
AMST
CLNN
CLNN
Q4 25
$2.0M
$18.1M
Q3 25
$2.6M
$22.3M
Q2 25
$3.1M
$22.1M
Q1 25
$25.3M
Q4 24
$27.3M
Q3 24
$31.6M
Q2 24
$40.3M
Q1 24
$45.1M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
AMST
AMST
CLNN
CLNN
Operating Cash FlowLast quarter
$-621.1K
$-4.8M
Free Cash FlowOCF − Capex
$-4.8M
FCF MarginFCF / Revenue
-6268.8%
Capex IntensityCapex / Revenue
36.4%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
AMST
AMST
CLNN
CLNN
Q4 25
$-621.1K
$-4.8M
Q3 25
$-415.8K
$-4.0M
Q2 25
$-439.4K
$-4.7M
Q1 25
$-5.0M
Q4 24
$-4.9M
Q3 24
$-3.0M
Q2 24
$-6.4M
Q1 24
$-7.1M
Free Cash Flow
AMST
AMST
CLNN
CLNN
Q4 25
$-4.8M
Q3 25
$-4.0M
Q2 25
Q1 25
Q4 24
$-4.9M
Q3 24
$-3.0M
Q2 24
$-6.4M
Q1 24
$-7.1M
FCF Margin
AMST
AMST
CLNN
CLNN
Q4 25
-6268.8%
Q3 25
-26686.7%
Q2 25
Q1 25
Q4 24
-5347.3%
Q3 24
-3475.9%
Q2 24
-6986.8%
Q1 24
-9716.4%
Capex Intensity
AMST
AMST
CLNN
CLNN
Q4 25
36.4%
Q3 25
73.3%
Q2 25
0.0%
Q1 25
0.0%
Q4 24
1.1%
Q3 24
1.1%
Q2 24
2.2%
Q1 24
15.1%

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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