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Side-by-side financial comparison of ANAPTYSBIO, INC (ANAB) and ALPHA & OMEGA SEMICONDUCTOR Ltd (AOSL). Click either name above to swap in a different company.

ALPHA & OMEGA SEMICONDUCTOR Ltd is the larger business by last-quarter revenue ($162.3M vs $108.2M, roughly 1.5× ANAPTYSBIO, INC). ANAPTYSBIO, INC runs the higher net margin — 45.8% vs -8.2%, a 54.0% gap on every dollar of revenue. On growth, ANAPTYSBIO, INC posted the faster year-over-year revenue change (151.1% vs -6.3%). ANAPTYSBIO, INC produced more free cash flow last quarter ($98.0M vs $-23.1M). Over the past eight quarters, ANAPTYSBIO, INC's revenue compounded faster (288.3% CAGR vs 4.0%).

AnaptysBio, Inc. is a clinical-stage biotechnology company focused on developing antibody-based immunotherapies for inflammatory diseases, immuno-oncology indications, and rare disease conditions. It primarily serves the U.S. market, advancing its innovative product candidate pipeline to address unmet medical needs via rigorous research and clinical development.

Alpha & Omega Semiconductor Ltd designs, manufactures and markets a broad portfolio of power semiconductors, including power MOSFETs, IGBTs, analog ICs and power management modules. Its products are applied across consumer electronics, industrial equipment, automotive systems, telecom and computing segments, with sales networks covering major global markets.

ANAB vs AOSL — Head-to-Head

Bigger by revenue
AOSL
AOSL
1.5× larger
AOSL
$162.3M
$108.2M
ANAB
Growing faster (revenue YoY)
ANAB
ANAB
+157.4% gap
ANAB
151.1%
-6.3%
AOSL
Higher net margin
ANAB
ANAB
54.0% more per $
ANAB
45.8%
-8.2%
AOSL
More free cash flow
ANAB
ANAB
$121.1M more FCF
ANAB
$98.0M
$-23.1M
AOSL
Faster 2-yr revenue CAGR
ANAB
ANAB
Annualised
ANAB
288.3%
4.0%
AOSL

Income Statement — Q4 FY2025 vs Q2 FY2026

Metric
ANAB
ANAB
AOSL
AOSL
Revenue
$108.2M
$162.3M
Net Profit
$49.6M
$-13.3M
Gross Margin
21.5%
Operating Margin
61.8%
-8.4%
Net Margin
45.8%
-8.2%
Revenue YoY
151.1%
-6.3%
Net Profit YoY
327.8%
-101.0%
EPS (diluted)
$1.64
$-0.45

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ANAB
ANAB
AOSL
AOSL
Q4 25
$108.2M
$162.3M
Q3 25
$76.3M
$182.5M
Q2 25
$22.3M
$176.5M
Q1 25
$27.8M
$164.6M
Q4 24
$43.1M
$173.2M
Q3 24
$30.0M
$181.9M
Q2 24
$11.0M
$161.3M
Q1 24
$7.2M
$150.1M
Net Profit
ANAB
ANAB
AOSL
AOSL
Q4 25
$49.6M
$-13.3M
Q3 25
$15.1M
$-2.1M
Q2 25
$-38.6M
$-77.1M
Q1 25
$-39.3M
$-10.8M
Q4 24
$-21.8M
$-6.6M
Q3 24
$-32.9M
$-2.5M
Q2 24
$-46.7M
$-2.7M
Q1 24
$-43.9M
$-11.2M
Gross Margin
ANAB
ANAB
AOSL
AOSL
Q4 25
21.5%
Q3 25
23.5%
Q2 25
23.4%
Q1 25
21.4%
Q4 24
23.1%
Q3 24
24.5%
Q2 24
25.7%
Q1 24
23.7%
Operating Margin
ANAB
ANAB
AOSL
AOSL
Q4 25
61.8%
-8.4%
Q3 25
45.5%
-2.5%
Q2 25
-117.5%
-6.6%
Q1 25
-99.2%
-6.5%
Q4 24
-22.4%
-3.4%
Q3 24
-75.8%
-0.1%
Q2 24
-367.5%
-0.9%
Q1 24
-587.8%
-7.0%
Net Margin
ANAB
ANAB
AOSL
AOSL
Q4 25
45.8%
-8.2%
Q3 25
19.8%
-1.2%
Q2 25
-173.5%
-43.7%
Q1 25
-141.6%
-6.6%
Q4 24
-50.5%
-3.8%
Q3 24
-109.4%
-1.4%
Q2 24
-425.3%
-1.7%
Q1 24
-612.0%
-7.5%
EPS (diluted)
ANAB
ANAB
AOSL
AOSL
Q4 25
$1.64
$-0.45
Q3 25
$0.52
$-0.07
Q2 25
$-1.34
$-2.61
Q1 25
$-1.28
$-0.37
Q4 24
$-0.63
$-0.23
Q3 24
$-1.14
$-0.09
Q2 24
$-1.71
$-0.09
Q1 24
$-1.64
$-0.39

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ANAB
ANAB
AOSL
AOSL
Cash + ST InvestmentsLiquidity on hand
$238.2M
$196.3M
Total DebtLower is stronger
Stockholders' EquityBook value
$37.2M
$818.8M
Total Assets
$364.4M
$1.0B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ANAB
ANAB
AOSL
AOSL
Q4 25
$238.2M
$196.3M
Q3 25
$109.8M
$223.5M
Q2 25
$44.3M
$153.1M
Q1 25
$98.6M
$169.4M
Q4 24
$123.1M
$182.6M
Q3 24
$191.6M
$176.0M
Q2 24
$71.8M
$175.1M
Q1 24
$53.7M
$174.4M
Total Debt
ANAB
ANAB
AOSL
AOSL
Q4 25
Q3 25
Q2 25
$14.9M
Q1 25
Q4 24
Q3 24
Q2 24
$26.7M
Q1 24
Stockholders' Equity
ANAB
ANAB
AOSL
AOSL
Q4 25
$37.2M
$818.8M
Q3 25
$-29.4M
$834.1M
Q2 25
$-44.7M
$822.3M
Q1 25
$34.0M
$886.3M
Q4 24
$70.9M
$902.6M
Q3 24
$84.4M
$895.3M
Q2 24
$9.9M
$891.6M
Q1 24
$47.8M
$888.9M
Total Assets
ANAB
ANAB
AOSL
AOSL
Q4 25
$364.4M
$1.0B
Q3 25
$353.1M
$1.0B
Q2 25
$335.3M
$1.0B
Q1 25
$422.1M
$1.1B
Q4 24
$483.8M
$1.1B
Q3 24
$493.4M
$1.1B
Q2 24
$427.4M
$1.1B
Q1 24
$405.8M
$1.2B
Debt / Equity
ANAB
ANAB
AOSL
AOSL
Q4 25
Q3 25
Q2 25
0.02×
Q1 25
Q4 24
Q3 24
Q2 24
0.03×
Q1 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ANAB
ANAB
AOSL
AOSL
Operating Cash FlowLast quarter
$98.0M
$-8.1M
Free Cash FlowOCF − Capex
$98.0M
$-23.1M
FCF MarginFCF / Revenue
90.5%
-14.2%
Capex IntensityCapex / Revenue
0.0%
9.2%
Cash ConversionOCF / Net Profit
1.98×
TTM Free Cash FlowTrailing 4 quarters
$19.6M
$-40.9M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ANAB
ANAB
AOSL
AOSL
Q4 25
$98.0M
$-8.1M
Q3 25
$-27.4M
$10.2M
Q2 25
$-40.2M
$-2.8M
Q1 25
$-10.7M
$7.4M
Q4 24
$-66.7M
$14.1M
Q3 24
$-10.1M
$11.0M
Q2 24
$-21.3M
$7.1M
Q1 24
$-37.3M
$28.2M
Free Cash Flow
ANAB
ANAB
AOSL
AOSL
Q4 25
$98.0M
$-23.1M
Q3 25
$-27.4M
$420.0K
Q2 25
$-40.3M
$-17.2M
Q1 25
$-10.7M
$-1.1M
Q4 24
$-66.9M
$6.6M
Q3 24
$-10.1M
$4.1M
Q2 24
$-21.4M
$-210.0K
Q1 24
$-37.3M
$20.5M
FCF Margin
ANAB
ANAB
AOSL
AOSL
Q4 25
90.5%
-14.2%
Q3 25
-35.9%
0.2%
Q2 25
-180.9%
-9.7%
Q1 25
-38.7%
-0.6%
Q4 24
-155.3%
3.8%
Q3 24
-33.7%
2.3%
Q2 24
-194.6%
-0.1%
Q1 24
-519.3%
13.7%
Capex Intensity
ANAB
ANAB
AOSL
AOSL
Q4 25
0.0%
9.2%
Q3 25
0.0%
5.4%
Q2 25
0.2%
8.1%
Q1 25
0.1%
5.1%
Q4 24
0.6%
4.3%
Q3 24
0.1%
3.8%
Q2 24
0.3%
4.5%
Q1 24
0.4%
5.2%
Cash Conversion
ANAB
ANAB
AOSL
AOSL
Q4 25
1.98×
Q3 25
-1.81×
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

ANAB
ANAB

Segment breakdown not available.

AOSL
AOSL

Power Discrete$101.0M62%
Power Ic$58.8M36%
Packaging And Testing Services$2.5M2%

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