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Side-by-side financial comparison of ANAPTYSBIO, INC (ANAB) and Orion Group Holdings Inc (ORN). Click either name above to swap in a different company.

Orion Group Holdings Inc is the larger business by last-quarter revenue ($216.3M vs $108.2M, roughly 2.0× ANAPTYSBIO, INC). ANAPTYSBIO, INC runs the higher net margin — 45.8% vs 2.2%, a 43.7% gap on every dollar of revenue. On growth, ANAPTYSBIO, INC posted the faster year-over-year revenue change (151.1% vs 14.6%). Over the past eight quarters, ANAPTYSBIO, INC's revenue compounded faster (288.3% CAGR vs 6.1%).

AnaptysBio, Inc. is a clinical-stage biotechnology company focused on developing antibody-based immunotherapies for inflammatory diseases, immuno-oncology indications, and rare disease conditions. It primarily serves the U.S. market, advancing its innovative product candidate pipeline to address unmet medical needs via rigorous research and clinical development.

Orion Corporation, founded in 1917 and headquartered at Espoo, Finland, is a globally operating Finnish company which develops, manufactures and markets human and veterinary pharmaceuticals and active pharmaceutical ingredients for global markets. All of the company's manufacturing sites and the majority of its R&D units are in Finland.

ANAB vs ORN — Head-to-Head

Bigger by revenue
ORN
ORN
2.0× larger
ORN
$216.3M
$108.2M
ANAB
Growing faster (revenue YoY)
ANAB
ANAB
+136.5% gap
ANAB
151.1%
14.6%
ORN
Higher net margin
ANAB
ANAB
43.7% more per $
ANAB
45.8%
2.2%
ORN
Faster 2-yr revenue CAGR
ANAB
ANAB
Annualised
ANAB
288.3%
6.1%
ORN

Income Statement — Q4 FY2025 vs Q1 FY2026

Metric
ANAB
ANAB
ORN
ORN
Revenue
$108.2M
$216.3M
Net Profit
$49.6M
$4.7M
Gross Margin
12.0%
Operating Margin
61.8%
Net Margin
45.8%
2.2%
Revenue YoY
151.1%
14.6%
Net Profit YoY
327.8%
435.7%
EPS (diluted)
$1.64
$0.12

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ANAB
ANAB
ORN
ORN
Q1 26
$216.3M
Q4 25
$108.2M
$233.2M
Q3 25
$76.3M
$225.1M
Q2 25
$22.3M
$205.3M
Q1 25
$27.8M
$188.7M
Q4 24
$43.1M
$216.9M
Q3 24
$30.0M
$226.7M
Q2 24
$11.0M
$192.2M
Net Profit
ANAB
ANAB
ORN
ORN
Q1 26
$4.7M
Q4 25
$49.6M
$-240.0K
Q3 25
$15.1M
$3.3M
Q2 25
$-38.6M
$841.0K
Q1 25
$-39.3M
$-1.4M
Q4 24
$-21.8M
$6.8M
Q3 24
$-32.9M
$4.3M
Q2 24
$-46.7M
$-6.6M
Gross Margin
ANAB
ANAB
ORN
ORN
Q1 26
12.0%
Q4 25
11.6%
Q3 25
13.2%
Q2 25
12.6%
Q1 25
12.2%
Q4 24
14.0%
Q3 24
11.9%
Q2 24
9.5%
Operating Margin
ANAB
ANAB
ORN
ORN
Q1 26
Q4 25
61.8%
2.2%
Q3 25
45.5%
2.4%
Q2 25
-117.5%
1.7%
Q1 25
-99.2%
0.4%
Q4 24
-22.4%
4.4%
Q3 24
-75.8%
3.4%
Q2 24
-367.5%
-1.4%
Net Margin
ANAB
ANAB
ORN
ORN
Q1 26
2.2%
Q4 25
45.8%
-0.1%
Q3 25
19.8%
1.5%
Q2 25
-173.5%
0.4%
Q1 25
-141.6%
-0.7%
Q4 24
-50.5%
3.1%
Q3 24
-109.4%
1.9%
Q2 24
-425.3%
-3.4%
EPS (diluted)
ANAB
ANAB
ORN
ORN
Q1 26
$0.12
Q4 25
$1.64
$-0.00
Q3 25
$0.52
$0.08
Q2 25
$-1.34
$0.02
Q1 25
$-1.28
$-0.04
Q4 24
$-0.63
$0.22
Q3 24
$-1.14
$0.12
Q2 24
$-1.71
$-0.20

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ANAB
ANAB
ORN
ORN
Cash + ST InvestmentsLiquidity on hand
$238.2M
$6.3M
Total DebtLower is stronger
Stockholders' EquityBook value
$37.2M
$166.7M
Total Assets
$364.4M
$478.7M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ANAB
ANAB
ORN
ORN
Q1 26
$6.3M
Q4 25
$238.2M
$1.6M
Q3 25
$109.8M
$4.9M
Q2 25
$44.3M
$1.7M
Q1 25
$98.6M
$13.0M
Q4 24
$123.1M
$28.3M
Q3 24
$191.6M
$28.3M
Q2 24
$71.8M
$4.8M
Total Debt
ANAB
ANAB
ORN
ORN
Q1 26
Q4 25
Q3 25
Q2 25
$33.4M
Q1 25
$23.3M
Q4 24
$23.2M
Q3 24
$28.0M
Q2 24
$60.3M
Stockholders' Equity
ANAB
ANAB
ORN
ORN
Q1 26
$166.7M
Q4 25
$37.2M
$159.0M
Q3 25
$-29.4M
$157.9M
Q2 25
$-44.7M
$153.2M
Q1 25
$34.0M
$150.8M
Q4 24
$70.9M
$150.7M
Q3 24
$84.4M
$142.4M
Q2 24
$9.9M
$111.1M
Total Assets
ANAB
ANAB
ORN
ORN
Q1 26
$478.7M
Q4 25
$364.4M
$414.7M
Q3 25
$353.1M
$422.4M
Q2 25
$335.3M
$432.7M
Q1 25
$422.1M
$416.3M
Q4 24
$483.8M
$417.3M
Q3 24
$493.4M
$430.3M
Q2 24
$427.4M
$414.0M
Debt / Equity
ANAB
ANAB
ORN
ORN
Q1 26
Q4 25
Q3 25
Q2 25
0.22×
Q1 25
0.15×
Q4 24
0.15×
Q3 24
0.20×
Q2 24
0.54×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ANAB
ANAB
ORN
ORN
Operating Cash FlowLast quarter
$98.0M
Free Cash FlowOCF − Capex
$98.0M
FCF MarginFCF / Revenue
90.5%
Capex IntensityCapex / Revenue
0.0%
Cash ConversionOCF / Net Profit
1.98×
TTM Free Cash FlowTrailing 4 quarters
$19.6M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ANAB
ANAB
ORN
ORN
Q1 26
Q4 25
$98.0M
$13.8M
Q3 25
$-27.4M
$23.3M
Q2 25
$-40.2M
$-5.6M
Q1 25
$-10.7M
$-3.4M
Q4 24
$-66.7M
$13.4M
Q3 24
$-10.1M
$37.5M
Q2 24
$-21.3M
$-15.3M
Free Cash Flow
ANAB
ANAB
ORN
ORN
Q1 26
Q4 25
$98.0M
$454.0K
Q3 25
$-27.4M
$13.9M
Q2 25
$-40.3M
$-12.7M
Q1 25
$-10.7M
$-12.5M
Q4 24
$-66.9M
$9.9M
Q3 24
$-10.1M
$33.3M
Q2 24
$-21.4M
$-20.0M
FCF Margin
ANAB
ANAB
ORN
ORN
Q1 26
Q4 25
90.5%
0.2%
Q3 25
-35.9%
6.2%
Q2 25
-180.9%
-6.2%
Q1 25
-38.7%
-6.6%
Q4 24
-155.3%
4.6%
Q3 24
-33.7%
14.7%
Q2 24
-194.6%
-10.4%
Capex Intensity
ANAB
ANAB
ORN
ORN
Q1 26
Q4 25
0.0%
5.7%
Q3 25
0.0%
4.2%
Q2 25
0.2%
3.5%
Q1 25
0.1%
4.8%
Q4 24
0.6%
1.6%
Q3 24
0.1%
1.8%
Q2 24
0.3%
2.4%
Cash Conversion
ANAB
ANAB
ORN
ORN
Q1 26
Q4 25
1.98×
Q3 25
-1.81×
7.05×
Q2 25
-6.61×
Q1 25
Q4 24
1.98×
Q3 24
8.79×
Q2 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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