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Side-by-side financial comparison of ANAPTYSBIO, INC (ANAB) and S&T BANCORP INC (STBA). Click either name above to swap in a different company.

ANAPTYSBIO, INC is the larger business by last-quarter revenue ($108.2M vs $102.1M, roughly 1.1× S&T BANCORP INC). ANAPTYSBIO, INC runs the higher net margin — 45.8% vs 34.4%, a 11.5% gap on every dollar of revenue. Over the past eight quarters, ANAPTYSBIO, INC's revenue compounded faster (288.3% CAGR vs 2.6%).

AnaptysBio, Inc. is a clinical-stage biotechnology company focused on developing antibody-based immunotherapies for inflammatory diseases, immuno-oncology indications, and rare disease conditions. It primarily serves the U.S. market, advancing its innovative product candidate pipeline to address unmet medical needs via rigorous research and clinical development.

U.S. Bancorp is an American multinational banking institution headquartered in Minneapolis, Minnesota and incorporated in Delaware. It is the 5th-largest bank in the United States as of 2025. As the largest bank in the Midwestern United States, it is considered systemically important by the Financial Stability Board. It is the parent company of its primary operating entity, U.S. Bank National Association, which does business as U.S. Bank. The company provides banking, investment, mortgage, tr...

ANAB vs STBA — Head-to-Head

Bigger by revenue
ANAB
ANAB
1.1× larger
ANAB
$108.2M
$102.1M
STBA
Higher net margin
ANAB
ANAB
11.5% more per $
ANAB
45.8%
34.4%
STBA
Faster 2-yr revenue CAGR
ANAB
ANAB
Annualised
ANAB
288.3%
2.6%
STBA

Income Statement — Q4 FY2025 vs Q1 FY2026

Metric
ANAB
ANAB
STBA
STBA
Revenue
$108.2M
$102.1M
Net Profit
$49.6M
$35.1M
Gross Margin
Operating Margin
61.8%
Net Margin
45.8%
34.4%
Revenue YoY
151.1%
Net Profit YoY
327.8%
5.0%
EPS (diluted)
$1.64
$0.94

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ANAB
ANAB
STBA
STBA
Q1 26
$102.1M
Q4 25
$108.2M
$105.3M
Q3 25
$76.3M
$103.0M
Q2 25
$22.3M
$100.1M
Q1 25
$27.8M
$93.8M
Q4 24
$43.1M
$94.3M
Q3 24
$30.0M
$96.4M
Q2 24
$11.0M
$96.9M
Net Profit
ANAB
ANAB
STBA
STBA
Q1 26
$35.1M
Q4 25
$49.6M
$34.0M
Q3 25
$15.1M
$35.0M
Q2 25
$-38.6M
$31.9M
Q1 25
$-39.3M
$33.4M
Q4 24
$-21.8M
$33.1M
Q3 24
$-32.9M
$32.6M
Q2 24
$-46.7M
$34.4M
Operating Margin
ANAB
ANAB
STBA
STBA
Q1 26
Q4 25
61.8%
40.3%
Q3 25
45.5%
42.6%
Q2 25
-117.5%
40.0%
Q1 25
-99.2%
44.5%
Q4 24
-22.4%
43.8%
Q3 24
-75.8%
43.0%
Q2 24
-367.5%
44.2%
Net Margin
ANAB
ANAB
STBA
STBA
Q1 26
34.4%
Q4 25
45.8%
32.3%
Q3 25
19.8%
33.9%
Q2 25
-173.5%
31.9%
Q1 25
-141.6%
35.6%
Q4 24
-50.5%
35.1%
Q3 24
-109.4%
33.8%
Q2 24
-425.3%
35.5%
EPS (diluted)
ANAB
ANAB
STBA
STBA
Q1 26
$0.94
Q4 25
$1.64
$0.88
Q3 25
$0.52
$0.91
Q2 25
$-1.34
$0.83
Q1 25
$-1.28
$0.87
Q4 24
$-0.63
$0.86
Q3 24
$-1.14
$0.85
Q2 24
$-1.71
$0.89

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ANAB
ANAB
STBA
STBA
Cash + ST InvestmentsLiquidity on hand
$238.2M
Total DebtLower is stronger
$100.8M
Stockholders' EquityBook value
$37.2M
$1.4B
Total Assets
$364.4M
$9.9B
Debt / EquityLower = less leverage
0.07×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ANAB
ANAB
STBA
STBA
Q1 26
Q4 25
$238.2M
$163.4M
Q3 25
$109.8M
$196.2M
Q2 25
$44.3M
$203.1M
Q1 25
$98.6M
$211.8M
Q4 24
$123.1M
$244.8M
Q3 24
$191.6M
$228.1M
Q2 24
$71.8M
$246.3M
Total Debt
ANAB
ANAB
STBA
STBA
Q1 26
$100.8M
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Stockholders' Equity
ANAB
ANAB
STBA
STBA
Q1 26
$1.4B
Q4 25
$37.2M
$1.5B
Q3 25
$-29.4M
$1.5B
Q2 25
$-44.7M
$1.4B
Q1 25
$34.0M
$1.4B
Q4 24
$70.9M
$1.4B
Q3 24
$84.4M
$1.4B
Q2 24
$9.9M
$1.3B
Total Assets
ANAB
ANAB
STBA
STBA
Q1 26
$9.9B
Q4 25
$364.4M
$9.9B
Q3 25
$353.1M
$9.8B
Q2 25
$335.3M
$9.8B
Q1 25
$422.1M
$9.7B
Q4 24
$483.8M
$9.7B
Q3 24
$493.4M
$9.6B
Q2 24
$427.4M
$9.6B
Debt / Equity
ANAB
ANAB
STBA
STBA
Q1 26
0.07×
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ANAB
ANAB
STBA
STBA
Operating Cash FlowLast quarter
$98.0M
Free Cash FlowOCF − Capex
$98.0M
FCF MarginFCF / Revenue
90.5%
Capex IntensityCapex / Revenue
0.0%
Cash ConversionOCF / Net Profit
1.98×
TTM Free Cash FlowTrailing 4 quarters
$19.6M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ANAB
ANAB
STBA
STBA
Q1 26
Q4 25
$98.0M
$133.6M
Q3 25
$-27.4M
$40.5M
Q2 25
$-40.2M
$28.3M
Q1 25
$-10.7M
$28.7M
Q4 24
$-66.7M
$173.4M
Q3 24
$-10.1M
$27.6M
Q2 24
$-21.3M
$44.7M
Free Cash Flow
ANAB
ANAB
STBA
STBA
Q1 26
Q4 25
$98.0M
$128.8M
Q3 25
$-27.4M
$39.9M
Q2 25
$-40.3M
$27.1M
Q1 25
$-10.7M
$27.0M
Q4 24
$-66.9M
$170.4M
Q3 24
$-10.1M
$26.9M
Q2 24
$-21.4M
$43.9M
FCF Margin
ANAB
ANAB
STBA
STBA
Q1 26
Q4 25
90.5%
122.4%
Q3 25
-35.9%
38.7%
Q2 25
-180.9%
27.1%
Q1 25
-38.7%
28.8%
Q4 24
-155.3%
180.7%
Q3 24
-33.7%
28.0%
Q2 24
-194.6%
45.3%
Capex Intensity
ANAB
ANAB
STBA
STBA
Q1 26
Q4 25
0.0%
4.5%
Q3 25
0.0%
0.6%
Q2 25
0.2%
1.2%
Q1 25
0.1%
1.8%
Q4 24
0.6%
3.1%
Q3 24
0.1%
0.7%
Q2 24
0.3%
0.9%
Cash Conversion
ANAB
ANAB
STBA
STBA
Q1 26
Q4 25
1.98×
3.93×
Q3 25
-1.81×
1.16×
Q2 25
0.89×
Q1 25
0.86×
Q4 24
5.24×
Q3 24
0.85×
Q2 24
1.30×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

ANAB
ANAB

Segment breakdown not available.

STBA
STBA

Net Interest Income$88.4M87%
Noninterest Income$13.6M13%

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