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Side-by-side financial comparison of Annovis Bio, Inc. (ANVS) and Aspire Biopharma Holdings, Inc. (ASBP). Click either name above to swap in a different company.

Annovis Bio, Inc. is a clinical-stage biotechnology company focused on developing novel therapies for neurodegenerative disorders including Alzheimer's disease and Parkinson's disease. It targets both neuronal and synaptic dysfunction, operates primarily in the U.S. biopharmaceutical market, and advances its therapeutic pipeline through clinical trials to address unmet medical needs for patients with chronic neurological conditions.

Aspire Biopharma Holdings, Inc. is a clinical-stage biopharmaceutical firm focused on developing novel therapeutic candidates for unmet needs in oncology and rare diseases, with primary operations across North America and key Asia-Pacific markets.

ANVS vs ASBP — Head-to-Head

Bigger by revenue
ASBP
ASBP
Infinity× larger
ASBP
$1.9K
$0
ANVS

Income Statement — Q4 FY2025 vs Q3 FY2025

Metric
ANVS
ANVS
ASBP
ASBP
Revenue
$0
$1.9K
Net Profit
$-9.8M
$-1.9M
Gross Margin
45.5%
Operating Margin
-59015.8%
Net Margin
-95337.1%
Revenue YoY
Net Profit YoY
-67.7%
-755.6%
EPS (diluted)
$-0.39
$-0.04

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ANVS
ANVS
ASBP
ASBP
Q4 25
$0
Q3 25
$0
$1.9K
Q2 25
$0
Q1 25
$0
Q4 24
$0
Q3 24
$0
Q2 24
$0
Q1 24
$0
Net Profit
ANVS
ANVS
ASBP
ASBP
Q4 25
$-9.8M
Q3 25
$-7.3M
$-1.9M
Q2 25
$-6.2M
Q1 25
$-5.5M
Q4 24
$-5.9M
Q3 24
$-12.6M
Q2 24
$-5.0M
Q1 24
$-1.1M
Gross Margin
ANVS
ANVS
ASBP
ASBP
Q4 25
Q3 25
45.5%
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
Operating Margin
ANVS
ANVS
ASBP
ASBP
Q4 25
Q3 25
-59015.8%
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
Net Margin
ANVS
ANVS
ASBP
ASBP
Q4 25
Q3 25
-95337.1%
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
EPS (diluted)
ANVS
ANVS
ASBP
ASBP
Q4 25
$-0.39
Q3 25
$-0.37
$-0.04
Q2 25
$-0.32
Q1 25
$-0.32
Q4 24
$-0.18
Q3 24
$-0.97
Q2 24
$-0.44
Q1 24
$-0.72

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ANVS
ANVS
ASBP
ASBP
Cash + ST InvestmentsLiquidity on hand
$19.5M
Total DebtLower is stronger
Stockholders' EquityBook value
$16.9M
$-11.5M
Total Assets
$21.1M
$2.4M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ANVS
ANVS
ASBP
ASBP
Q4 25
$19.5M
Q3 25
$15.3M
Q2 25
$17.1M
Q1 25
$22.2M
Q4 24
$10.6M
Q3 24
$12.6M
Q2 24
$4.0M
Q1 24
$3.1M
Stockholders' Equity
ANVS
ANVS
ASBP
ASBP
Q4 25
$16.9M
Q3 25
$13.2M
$-11.5M
Q2 25
$18.3M
Q1 25
$24.1M
Q4 24
$9.3M
Q3 24
$7.1M
Q2 24
$-1.8M
Q1 24
$-3.4M
Total Assets
ANVS
ANVS
ASBP
ASBP
Q4 25
$21.1M
Q3 25
$17.2M
$2.4M
Q2 25
$21.5M
Q1 25
$26.7M
Q4 24
$13.9M
Q3 24
$14.4M
Q2 24
$5.0M
Q1 24
$7.8M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ANVS
ANVS
ASBP
ASBP
Operating Cash FlowLast quarter
$-8.9M
$-1.1M
Free Cash FlowOCF − Capex
FCF MarginFCF / Revenue
Capex IntensityCapex / Revenue
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ANVS
ANVS
ASBP
ASBP
Q4 25
$-8.9M
Q3 25
$-3.5M
$-1.1M
Q2 25
$-5.1M
Q1 25
$-8.1M
Q4 24
$-8.3M
Q3 24
$-3.2M
Q2 24
$-3.4M
Q1 24
$-7.0M

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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