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Side-by-side financial comparison of Applied Therapeutics, Inc. (APLT) and ReTo Eco-Solutions, Inc. (RETO). Click either name above to swap in a different company.

ReTo Eco-Solutions, Inc. is the larger business by last-quarter revenue ($1.0M vs $1.0M, roughly 1.0× Applied Therapeutics, Inc.). ReTo Eco-Solutions, Inc. runs the higher net margin — -131.6% vs -1899.0%, a 1767.4% gap on every dollar of revenue. On growth, Applied Therapeutics, Inc. posted the faster year-over-year revenue change (719.7% vs 36.6%).

Relief Therapeutics is a Swiss biopharmaceutical company based in Geneva. The company focuses on developing drugs for serious diseases with few or no existing treatment options. Its lead compound, RLF-100, is a synthetic form of a natural peptide that protects the lung. The company was incorporated as Relief Therapeutics Holdings AG (RFLB.S) and listed on the SIX Swiss Exchange in 2016.

ReTo Eco-Solutions, Inc. develops and supplies eco-friendly construction materials, environmental remediation services, and solid waste treatment solutions. Its core offerings include recycled construction aggregates, soil improvement products, and ecological restoration systems, primarily serving infrastructure, real estate, and environmental conservation sectors across the Chinese market.

APLT vs RETO — Head-to-Head

Bigger by revenue
RETO
RETO
1.0× larger
RETO
$1.0M
$1.0M
APLT
Growing faster (revenue YoY)
APLT
APLT
+683.1% gap
APLT
719.7%
36.6%
RETO
Higher net margin
RETO
RETO
1767.4% more per $
RETO
-131.6%
-1899.0%
APLT

Income Statement — Q3 FY2025 vs Q2 FY2025

Metric
APLT
APLT
RETO
RETO
Revenue
$1.0M
$1.0M
Net Profit
$-19.0M
$-1.4M
Gross Margin
17.7%
Operating Margin
-1675.8%
-133.0%
Net Margin
-1899.0%
-131.6%
Revenue YoY
719.7%
36.6%
Net Profit YoY
72.3%
-103.5%
EPS (diluted)
$-0.13

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
APLT
APLT
RETO
RETO
Q3 25
$1.0M
Q2 25
$0
$1.0M
Q1 25
$0
Q4 24
$-1.0K
Q2 24
$144.0K
$768.4K
Q1 24
$190.0K
Q4 23
$-667.0K
Q3 23
$0
Net Profit
APLT
APLT
RETO
RETO
Q3 25
$-19.0M
Q2 25
$-21.3M
$-1.4M
Q1 25
$-21.8M
Q4 24
$44.0M
Q2 24
$2.9M
$-678.5K
Q1 24
$-83.9M
Q4 23
$-37.7M
Q3 23
$-42.4M
Gross Margin
APLT
APLT
RETO
RETO
Q3 25
Q2 25
17.7%
Q1 25
Q4 24
Q2 24
43.3%
Q1 24
Q4 23
Q3 23
Operating Margin
APLT
APLT
RETO
RETO
Q3 25
-1675.8%
Q2 25
-133.0%
Q1 25
Q4 24
3302300.0%
Q2 24
-14194.4%
-68.0%
Q1 24
-11101.6%
Q4 23
3149.3%
Q3 23
Net Margin
APLT
APLT
RETO
RETO
Q3 25
-1899.0%
Q2 25
-131.6%
Q1 25
Q4 24
-4400700.0%
Q2 24
2012.5%
-88.3%
Q1 24
-44177.9%
Q4 23
5649.0%
Q3 23
EPS (diluted)
APLT
APLT
RETO
RETO
Q3 25
$-0.13
Q2 25
$-0.15
Q1 25
$-0.15
Q4 24
$0.52
Q2 24
$-0.13
$-0.25
Q1 24
$-0.67
Q4 23
$-0.40
Q3 23
$-0.47

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
APLT
APLT
RETO
RETO
Cash + ST InvestmentsLiquidity on hand
$11.9M
$2.5M
Total DebtLower is stronger
Stockholders' EquityBook value
$-561.0K
$30.4M
Total Assets
$34.4M
$41.4M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
APLT
APLT
RETO
RETO
Q3 25
$11.9M
Q2 25
$30.4M
$2.5M
Q1 25
$50.8M
Q4 24
$79.4M
Q2 24
$122.2M
$1.6M
Q1 24
$146.5M
Q4 23
$49.9M
Q3 23
$37.5M
Stockholders' Equity
APLT
APLT
RETO
RETO
Q3 25
$-561.0K
Q2 25
$17.4M
$30.4M
Q1 25
$36.7M
Q4 24
$57.0M
Q2 24
$72.4M
$13.3M
Q1 24
$67.3M
Q4 23
$-17.1M
Q3 23
$-11.0M
Total Assets
APLT
APLT
RETO
RETO
Q3 25
$34.4M
Q2 25
$37.3M
$41.4M
Q1 25
$56.9M
Q4 24
$86.7M
Q2 24
$127.8M
$33.7M
Q1 24
$151.2M
Q4 23
$54.8M
Q3 23
$45.2M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
APLT
APLT
RETO
RETO
Operating Cash FlowLast quarter
$-18.4M
$-1.6M
Free Cash FlowOCF − Capex
$-1.7M
FCF MarginFCF / Revenue
-157.4%
Capex IntensityCapex / Revenue
5.1%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
APLT
APLT
RETO
RETO
Q3 25
$-18.4M
Q2 25
$-20.3M
$-1.6M
Q1 25
$-28.6M
Q4 24
$-19.5M
Q2 24
$-22.6M
$-4.8M
Q1 24
$-18.9M
Q4 23
$-17.0M
Q3 23
$-14.7M
Free Cash Flow
APLT
APLT
RETO
RETO
Q3 25
Q2 25
$-1.7M
Q1 25
Q4 24
Q2 24
Q1 24
Q4 23
Q3 23
FCF Margin
APLT
APLT
RETO
RETO
Q3 25
Q2 25
-157.4%
Q1 25
Q4 24
Q2 24
Q1 24
Q4 23
Q3 23
Capex Intensity
APLT
APLT
RETO
RETO
Q3 25
Q2 25
5.1%
Q1 25
Q4 24
Q2 24
Q1 24
Q4 23
Q3 23
Cash Conversion
APLT
APLT
RETO
RETO
Q3 25
Q2 25
Q1 25
Q4 24
-0.44×
Q2 24
-7.80×
Q1 24
Q4 23
Q3 23

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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