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Side-by-side financial comparison of Aptorum Group Ltd (APM) and iSpecimen Inc. (ISPC). Click either name above to swap in a different company.

iSpecimen Inc. is the larger business by last-quarter revenue ($713.1K vs $442.8K, roughly 1.6× Aptorum Group Ltd). Aptorum Group Ltd runs the higher net margin — -63.8% vs -146.9%, a 83.0% gap on every dollar of revenue.

Aptorum Group Ltd is a global biopharmaceutical enterprise dedicated to researching, developing and commercializing innovative therapeutic and diagnostic solutions. Its core focus areas cover infectious diseases, women’s health, and rare disorders, with key markets spanning North America and the Asia-Pacific region.

Specimen Products is a Chicago-based manufacturer of custom guitars, tube amplifiers, and audio horn speakers led by luthier Ian Schneller. Specimen Products also offers courses in guitar and tube amplifier design, construction, and repair through their Chicago School of Guitar Making. The Specimen workshop offers repair services to the general public, making use of their collection of parts from rare and vintage manufacturers.

APM vs ISPC — Head-to-Head

Bigger by revenue
ISPC
ISPC
1.6× larger
ISPC
$713.1K
$442.8K
APM
Higher net margin
APM
APM
83.0% more per $
APM
-63.8%
-146.9%
ISPC

Income Statement — Q4 FY2025 vs Q2 FY2025

Metric
APM
APM
ISPC
ISPC
Revenue
$442.8K
$713.1K
Net Profit
$-282.5K
$-1.0M
Gross Margin
44.4%
Operating Margin
-52.6%
-255.4%
Net Margin
-63.8%
-146.9%
Revenue YoY
-75.1%
Net Profit YoY
50.3%
EPS (diluted)
$-0.04
$-0.42

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
APM
APM
ISPC
ISPC
Q4 25
$442.8K
Q3 25
$208.8K
Q2 25
$713.1K
Q1 25
$1.1M
Q4 24
$1.5M
Q3 24
$2.7M
Q2 24
$2.9M
Q1 24
$2.3M
Net Profit
APM
APM
ISPC
ISPC
Q4 25
$-282.5K
Q3 25
$-614.0K
Q2 25
$-1.0M
Q1 25
$-1.7M
Q4 24
$-6.0M
Q3 24
$-1.4M
Q2 24
$-2.1M
Q1 24
$-2.9M
Gross Margin
APM
APM
ISPC
ISPC
Q4 25
Q3 25
Q2 25
44.4%
Q1 25
42.4%
Q4 24
13.5%
Q3 24
43.4%
Q2 24
51.9%
Q1 24
58.4%
Operating Margin
APM
APM
ISPC
ISPC
Q4 25
-52.6%
Q3 25
-71.9%
Q2 25
-255.4%
Q1 25
-154.9%
Q4 24
-395.8%
Q3 24
-64.1%
Q2 24
-76.2%
Q1 24
-131.0%
Net Margin
APM
APM
ISPC
ISPC
Q4 25
-63.8%
Q3 25
-294.0%
Q2 25
-146.9%
Q1 25
-156.8%
Q4 24
-409.8%
Q3 24
-54.1%
Q2 24
-73.6%
Q1 24
-126.7%
EPS (diluted)
APM
APM
ISPC
ISPC
Q4 25
$-0.04
Q3 25
$-0.09
Q2 25
$-0.42
Q1 25
$-0.71
Q4 24
$-5.40
Q3 24
$-2.10
Q2 24
$-3.72
Q1 24
$-6.36

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
APM
APM
ISPC
ISPC
Cash + ST InvestmentsLiquidity on hand
$3.5M
Total DebtLower is stronger
Stockholders' EquityBook value
$23.1M
$622.0K
Total Assets
$18.7M
$6.0M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
APM
APM
ISPC
ISPC
Q4 25
$3.5M
Q3 25
$56.8K
Q2 25
Q1 25
Q4 24
$1.9M
Q3 24
$1.8M
Q2 24
$2.2M
Q1 24
$2.1M
Stockholders' Equity
APM
APM
ISPC
ISPC
Q4 25
$23.1M
Q3 25
$22.5M
Q2 25
$622.0K
Q1 25
$1.7M
Q4 24
$3.3M
Q3 24
$4.7M
Q2 24
$6.1M
Q1 24
$6.8M
Total Assets
APM
APM
ISPC
ISPC
Q4 25
$18.7M
Q3 25
$17.6M
Q2 25
$6.0M
Q1 25
$6.8M
Q4 24
$9.4M
Q3 24
$11.3M
Q2 24
$11.9M
Q1 24
$12.5M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
APM
APM
ISPC
ISPC
Operating Cash FlowLast quarter
$-145.9K
$-192.2K
Free Cash FlowOCF − Capex
FCF MarginFCF / Revenue
Capex IntensityCapex / Revenue
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
APM
APM
ISPC
ISPC
Q4 25
$-145.9K
Q3 25
$-484.3K
Q2 25
$-192.2K
Q1 25
$-1.1M
Q4 24
$-3.6M
Q3 24
$-1.1M
Q2 24
$-1.5M
Q1 24
$-2.1M
Free Cash Flow
APM
APM
ISPC
ISPC
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
$-3.6M
Q3 24
$-1.1M
Q2 24
Q1 24
$-2.1M
FCF Margin
APM
APM
ISPC
ISPC
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
-242.7%
Q3 24
-41.1%
Q2 24
Q1 24
-90.9%
Capex Intensity
APM
APM
ISPC
ISPC
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
0.5%
Q3 24
0.5%
Q2 24
0.0%
Q1 24
0.4%

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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