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Side-by-side financial comparison of APPIAN CORP (APPN) and OPKO HEALTH, INC. (OPK). Click either name above to swap in a different company.

APPIAN CORP is the larger business by last-quarter revenue ($202.9M vs $148.5M, roughly 1.4× OPKO HEALTH, INC.). APPIAN CORP runs the higher net margin — -2.5% vs -21.1%, a 18.5% gap on every dollar of revenue. On growth, APPIAN CORP posted the faster year-over-year revenue change (21.7% vs -19.2%). APPIAN CORP produced more free cash flow last quarter ($270.0K vs $-28.6M). Over the past eight quarters, APPIAN CORP's revenue compounded faster (16.4% CAGR vs -7.5%).

Appian Corporation is an American cloud computing and enterprise software company headquartered in McLean, Virginia, part of the Dulles Technology Corridor. The company sells a platform as a service (PaaS) for building enterprise software applications. It is focused on low-code development, process mining, business process management, and case management markets in North America, Europe, the Middle East and Southeast Asia.

OPKO Health, Inc. is a medical test and medication company focused on diagnostics and pharmaceuticals. The company is a publicly traded company on NASDAQ and TASE under the symbol "OPK".

APPN vs OPK — Head-to-Head

Bigger by revenue
APPN
APPN
1.4× larger
APPN
$202.9M
$148.5M
OPK
Growing faster (revenue YoY)
APPN
APPN
+40.9% gap
APPN
21.7%
-19.2%
OPK
Higher net margin
APPN
APPN
18.5% more per $
APPN
-2.5%
-21.1%
OPK
More free cash flow
APPN
APPN
$28.9M more FCF
APPN
$270.0K
$-28.6M
OPK
Faster 2-yr revenue CAGR
APPN
APPN
Annualised
APPN
16.4%
-7.5%
OPK

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
APPN
APPN
OPK
OPK
Revenue
$202.9M
$148.5M
Net Profit
$-5.1M
$-31.3M
Gross Margin
64.8%
43.1%
Operating Margin
-0.3%
-25.8%
Net Margin
-2.5%
-21.1%
Revenue YoY
21.7%
-19.2%
Net Profit YoY
62.6%
-322.8%
EPS (diluted)
$-0.06
$-0.04

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
APPN
APPN
OPK
OPK
Q4 25
$202.9M
$148.5M
Q3 25
$187.0M
$151.7M
Q2 25
$170.6M
$156.8M
Q1 25
$166.4M
$150.0M
Q4 24
$166.7M
$183.6M
Q3 24
$154.1M
$173.6M
Q2 24
$146.4M
$182.2M
Q1 24
$149.8M
$173.7M
Net Profit
APPN
APPN
OPK
OPK
Q4 25
$-5.1M
$-31.3M
Q3 25
$7.8M
$21.6M
Q2 25
$-312.0K
$-148.4M
Q1 25
$-1.2M
$-67.6M
Q4 24
$-13.6M
$14.0M
Q3 24
$-2.1M
$24.9M
Q2 24
$-43.6M
$-10.3M
Q1 24
$-32.9M
$-81.8M
Gross Margin
APPN
APPN
OPK
OPK
Q4 25
64.8%
43.1%
Q3 25
75.8%
32.9%
Q2 25
74.3%
31.5%
Q1 25
76.6%
28.4%
Q4 24
67.8%
46.1%
Q3 24
75.9%
23.1%
Q2 24
73.1%
28.4%
Q1 24
74.6%
24.2%
Operating Margin
APPN
APPN
OPK
OPK
Q4 25
-0.3%
-25.8%
Q3 25
7.0%
31.7%
Q2 25
-6.4%
-38.3%
Q1 25
-0.5%
-44.8%
Q4 24
3.0%
-18.0%
Q3 24
-4.6%
8.2%
Q2 24
-26.8%
-33.9%
Q1 24
-13.0%
-41.2%
Net Margin
APPN
APPN
OPK
OPK
Q4 25
-2.5%
-21.1%
Q3 25
4.2%
14.3%
Q2 25
-0.2%
-94.7%
Q1 25
-0.7%
-45.1%
Q4 24
-8.2%
7.6%
Q3 24
-1.4%
14.3%
Q2 24
-29.8%
-5.7%
Q1 24
-22.0%
-47.1%
EPS (diluted)
APPN
APPN
OPK
OPK
Q4 25
$-0.06
$-0.04
Q3 25
$0.10
$0.03
Q2 25
$0.00
$-0.19
Q1 25
$-0.02
$-0.10
Q4 24
$-0.18
$0.02
Q3 24
$-0.03
$0.03
Q2 24
$-0.60
$-0.01
Q1 24
$-0.45
$-0.12

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
APPN
APPN
OPK
OPK
Cash + ST InvestmentsLiquidity on hand
$187.2M
$364.4M
Total DebtLower is stronger
$240.8M
$344.0M
Stockholders' EquityBook value
$-47.0M
$1.3B
Total Assets
$691.4M
$1.9B
Debt / EquityLower = less leverage
0.27×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
APPN
APPN
OPK
OPK
Q4 25
$187.2M
$364.4M
Q3 25
$191.6M
$412.0M
Q2 25
$184.8M
$267.3M
Q1 25
$199.7M
$428.8M
Q4 24
$159.9M
$426.6M
Q3 24
$99.2M
$400.1M
Q2 24
$120.8M
$40.6M
Q1 24
$170.1M
$75.6M
Total Debt
APPN
APPN
OPK
OPK
Q4 25
$240.8M
$344.0M
Q3 25
$245.7M
$344.2M
Q2 25
$245.6M
$343.3M
Q1 25
$248.0M
$439.2M
Q4 24
$250.4M
$437.2M
Q3 24
$252.8M
$441.0M
Q2 24
$254.0M
$201.9M
Q1 24
$255.1M
$350.1M
Stockholders' Equity
APPN
APPN
OPK
OPK
Q4 25
$-47.0M
$1.3B
Q3 25
$-48.5M
$1.3B
Q2 25
$-53.7M
$1.3B
Q1 25
$-31.7M
$1.3B
Q4 24
$-32.6M
$1.4B
Q3 24
$-49.8M
$1.4B
Q2 24
$-45.7M
$1.4B
Q1 24
$-9.7M
$1.3B
Total Assets
APPN
APPN
OPK
OPK
Q4 25
$691.4M
$1.9B
Q3 25
$611.7M
$2.0B
Q2 25
$590.7M
$2.0B
Q1 25
$592.9M
$2.1B
Q4 24
$621.0M
$2.2B
Q3 24
$549.9M
$2.3B
Q2 24
$554.6M
$2.0B
Q1 24
$595.4M
$2.0B
Debt / Equity
APPN
APPN
OPK
OPK
Q4 25
0.27×
Q3 25
0.26×
Q2 25
0.26×
Q1 25
0.33×
Q4 24
0.32×
Q3 24
0.31×
Q2 24
0.14×
Q1 24
0.28×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
APPN
APPN
OPK
OPK
Operating Cash FlowLast quarter
$1.1M
$-25.9M
Free Cash FlowOCF − Capex
$270.0K
$-28.6M
FCF MarginFCF / Revenue
0.1%
-19.3%
Capex IntensityCapex / Revenue
0.4%
1.8%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$59.6M
$-190.8M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
APPN
APPN
OPK
OPK
Q4 25
$1.1M
$-25.9M
Q3 25
$18.7M
$-34.6M
Q2 25
$-1.9M
$-83.4M
Q1 25
$45.0M
$-34.6M
Q4 24
$13.9M
$-44.4M
Q3 24
$-8.2M
$-77.1M
Q2 24
$-17.6M
$-26.4M
Q1 24
$18.9M
$-35.6M
Free Cash Flow
APPN
APPN
OPK
OPK
Q4 25
$270.0K
$-28.6M
Q3 25
$18.1M
$-37.8M
Q2 25
$-3.1M
$-86.7M
Q1 25
$44.3M
$-37.7M
Q4 24
$13.4M
$-49.8M
Q3 24
$-8.6M
$-85.0M
Q2 24
$-18.3M
$-33.7M
Q1 24
$16.7M
$-40.0M
FCF Margin
APPN
APPN
OPK
OPK
Q4 25
0.1%
-19.3%
Q3 25
9.7%
-24.9%
Q2 25
-1.8%
-55.3%
Q1 25
26.6%
-25.2%
Q4 24
8.0%
-27.1%
Q3 24
-5.6%
-49.0%
Q2 24
-12.5%
-18.5%
Q1 24
11.1%
-23.0%
Capex Intensity
APPN
APPN
OPK
OPK
Q4 25
0.4%
1.8%
Q3 25
0.3%
2.1%
Q2 25
0.7%
2.1%
Q1 25
0.4%
2.1%
Q4 24
0.3%
2.9%
Q3 24
0.2%
4.6%
Q2 24
0.5%
4.0%
Q1 24
1.5%
2.6%
Cash Conversion
APPN
APPN
OPK
OPK
Q4 25
Q3 25
2.39×
-1.60×
Q2 25
Q1 25
Q4 24
-3.17×
Q3 24
-3.10×
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

APPN
APPN

Subscriptions Software And Support$162.3M80%
Professional Services$40.6M20%

OPK
OPK

Services$71.1M48%
Transfer Of Intellectual Property And Other$33.7M23%
IE$22.1M15%
Rayaldee$8.8M6%
Barda Agreement$6.8M5%
MX$6.3M4%

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