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Side-by-side financial comparison of APPIAN CORP (APPN) and REPLIGEN CORP (RGEN). Click either name above to swap in a different company.

APPIAN CORP is the larger business by last-quarter revenue ($202.9M vs $197.9M, roughly 1.0× REPLIGEN CORP). REPLIGEN CORP runs the higher net margin — 6.7% vs -2.5%, a 9.2% gap on every dollar of revenue. On growth, APPIAN CORP posted the faster year-over-year revenue change (21.7% vs 13.6%). REPLIGEN CORP produced more free cash flow last quarter ($17.6M vs $270.0K). Over the past eight quarters, APPIAN CORP's revenue compounded faster (16.4% CAGR vs 14.4%).

Appian Corporation is an American cloud computing and enterprise software company headquartered in McLean, Virginia, part of the Dulles Technology Corridor. The company sells a platform as a service (PaaS) for building enterprise software applications. It is focused on low-code development, process mining, business process management, and case management markets in North America, Europe, the Middle East and Southeast Asia.

Repligen Corporation is a global life sciences company devoted to the development and commercialization of innovative bioprocessing technologies and systems that enable efficiencies in the process of manufacturing biological drugs.2025 The company is based in Waltham, Massachusetts,2014 and was incorporated in Delaware in 1981. A public company, Repligen is listed on the NASDAQ exchange under the symbol RGEN. As of 2025, Repligen employs over 1,900 employees globally and serves primarily biop...

APPN vs RGEN — Head-to-Head

Bigger by revenue
APPN
APPN
1.0× larger
APPN
$202.9M
$197.9M
RGEN
Growing faster (revenue YoY)
APPN
APPN
+8.1% gap
APPN
21.7%
13.6%
RGEN
Higher net margin
RGEN
RGEN
9.2% more per $
RGEN
6.7%
-2.5%
APPN
More free cash flow
RGEN
RGEN
$17.3M more FCF
RGEN
$17.6M
$270.0K
APPN
Faster 2-yr revenue CAGR
APPN
APPN
Annualised
APPN
16.4%
14.4%
RGEN

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
APPN
APPN
RGEN
RGEN
Revenue
$202.9M
$197.9M
Net Profit
$-5.1M
$13.3M
Gross Margin
64.8%
52.5%
Operating Margin
-0.3%
9.0%
Net Margin
-2.5%
6.7%
Revenue YoY
21.7%
13.6%
Net Profit YoY
62.6%
143.9%
EPS (diluted)
$-0.06
$0.24

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
APPN
APPN
RGEN
RGEN
Q4 25
$202.9M
$197.9M
Q3 25
$187.0M
$188.8M
Q2 25
$170.6M
$182.4M
Q1 25
$166.4M
$169.2M
Q4 24
$166.7M
$174.1M
Q3 24
$154.1M
$154.9M
Q2 24
$146.4M
$154.1M
Q1 24
$149.8M
$151.3M
Net Profit
APPN
APPN
RGEN
RGEN
Q4 25
$-5.1M
$13.3M
Q3 25
$7.8M
$14.9M
Q2 25
$-312.0K
$14.9M
Q1 25
$-1.2M
$5.8M
Q4 24
$-13.6M
$-30.3M
Q3 24
$-2.1M
$-654.0K
Q2 24
$-43.6M
$3.3M
Q1 24
$-32.9M
$2.1M
Gross Margin
APPN
APPN
RGEN
RGEN
Q4 25
64.8%
52.5%
Q3 25
75.8%
53.2%
Q2 25
74.3%
50.0%
Q1 25
76.6%
53.6%
Q4 24
67.8%
26.1%
Q3 24
75.9%
50.0%
Q2 24
73.1%
49.8%
Q1 24
74.6%
49.5%
Operating Margin
APPN
APPN
RGEN
RGEN
Q4 25
-0.3%
9.0%
Q3 25
7.0%
8.9%
Q2 25
-6.4%
7.6%
Q1 25
-0.5%
3.9%
Q4 24
3.0%
-17.7%
Q3 24
-4.6%
-5.1%
Q2 24
-26.8%
1.0%
Q1 24
-13.0%
1.3%
Net Margin
APPN
APPN
RGEN
RGEN
Q4 25
-2.5%
6.7%
Q3 25
4.2%
7.9%
Q2 25
-0.2%
8.2%
Q1 25
-0.7%
3.4%
Q4 24
-8.2%
-17.4%
Q3 24
-1.4%
-0.4%
Q2 24
-29.8%
2.2%
Q1 24
-22.0%
1.4%
EPS (diluted)
APPN
APPN
RGEN
RGEN
Q4 25
$-0.06
$0.24
Q3 25
$0.10
$0.26
Q2 25
$0.00
$0.26
Q1 25
$-0.02
$0.10
Q4 24
$-0.18
$-0.55
Q3 24
$-0.03
$-0.01
Q2 24
$-0.60
$0.06
Q1 24
$-0.45
$0.04

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
APPN
APPN
RGEN
RGEN
Cash + ST InvestmentsLiquidity on hand
$187.2M
$767.6M
Total DebtLower is stronger
$240.8M
$542.2M
Stockholders' EquityBook value
$-47.0M
$2.1B
Total Assets
$691.4M
$2.9B
Debt / EquityLower = less leverage
0.26×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
APPN
APPN
RGEN
RGEN
Q4 25
$187.2M
$767.6M
Q3 25
$191.6M
$748.7M
Q2 25
$184.8M
$708.9M
Q1 25
$199.7M
$697.2M
Q4 24
$159.9M
$757.4M
Q3 24
$99.2M
$784.0M
Q2 24
$120.8M
$809.1M
Q1 24
$170.1M
$780.6M
Total Debt
APPN
APPN
RGEN
RGEN
Q4 25
$240.8M
$542.2M
Q3 25
$245.7M
$537.9M
Q2 25
$245.6M
Q1 25
$248.0M
Q4 24
$250.4M
$525.6M
Q3 24
$252.8M
Q2 24
$254.0M
Q1 24
$255.1M
Stockholders' Equity
APPN
APPN
RGEN
RGEN
Q4 25
$-47.0M
$2.1B
Q3 25
$-48.5M
$2.1B
Q2 25
$-53.7M
$2.1B
Q1 25
$-31.7M
$2.0B
Q4 24
$-32.6M
$2.0B
Q3 24
$-49.8M
$2.0B
Q2 24
$-45.7M
$2.0B
Q1 24
$-9.7M
$2.0B
Total Assets
APPN
APPN
RGEN
RGEN
Q4 25
$691.4M
$2.9B
Q3 25
$611.7M
$2.9B
Q2 25
$590.7M
$2.9B
Q1 25
$592.9M
$2.9B
Q4 24
$621.0M
$2.8B
Q3 24
$549.9M
$2.8B
Q2 24
$554.6M
$2.9B
Q1 24
$595.4M
$2.8B
Debt / Equity
APPN
APPN
RGEN
RGEN
Q4 25
0.26×
Q3 25
0.26×
Q2 25
Q1 25
Q4 24
0.27×
Q3 24
Q2 24
Q1 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
APPN
APPN
RGEN
RGEN
Operating Cash FlowLast quarter
$1.1M
$25.7M
Free Cash FlowOCF − Capex
$270.0K
$17.6M
FCF MarginFCF / Revenue
0.1%
8.9%
Capex IntensityCapex / Revenue
0.4%
4.1%
Cash ConversionOCF / Net Profit
1.93×
TTM Free Cash FlowTrailing 4 quarters
$59.6M
$93.9M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
APPN
APPN
RGEN
RGEN
Q4 25
$1.1M
$25.7M
Q3 25
$18.7M
$48.1M
Q2 25
$-1.9M
$28.6M
Q1 25
$45.0M
$15.0M
Q4 24
$13.9M
$39.2M
Q3 24
$-8.2M
$49.3M
Q2 24
$-17.6M
$42.2M
Q1 24
$18.9M
$44.7M
Free Cash Flow
APPN
APPN
RGEN
RGEN
Q4 25
$270.0K
$17.6M
Q3 25
$18.1M
$43.4M
Q2 25
$-3.1M
$21.5M
Q1 25
$44.3M
$11.4M
Q4 24
$13.4M
$33.6M
Q3 24
$-8.6M
$42.3M
Q2 24
$-18.3M
$37.4M
Q1 24
$16.7M
$36.4M
FCF Margin
APPN
APPN
RGEN
RGEN
Q4 25
0.1%
8.9%
Q3 25
9.7%
23.0%
Q2 25
-1.8%
11.8%
Q1 25
26.6%
6.8%
Q4 24
8.0%
19.3%
Q3 24
-5.6%
27.3%
Q2 24
-12.5%
24.3%
Q1 24
11.1%
24.0%
Capex Intensity
APPN
APPN
RGEN
RGEN
Q4 25
0.4%
4.1%
Q3 25
0.3%
2.5%
Q2 25
0.7%
3.9%
Q1 25
0.4%
2.1%
Q4 24
0.3%
3.2%
Q3 24
0.2%
4.5%
Q2 24
0.5%
3.1%
Q1 24
1.5%
5.5%
Cash Conversion
APPN
APPN
RGEN
RGEN
Q4 25
1.93×
Q3 25
2.39×
3.23×
Q2 25
1.92×
Q1 25
2.57×
Q4 24
Q3 24
Q2 24
12.70×
Q1 24
21.35×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

APPN
APPN

Subscriptions Software And Support$162.3M80%
Professional Services$40.6M20%

RGEN
RGEN

Segment breakdown not available.

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