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Side-by-side financial comparison of ARDELYX, INC. (ARDX) and MANNKIND CORP (MNKD). Click either name above to swap in a different company.
ARDELYX, INC. is the larger business by last-quarter revenue ($125.2M vs $112.0M, roughly 1.1× MANNKIND CORP). ARDELYX, INC. runs the higher net margin — -0.3% vs -14.2%, a 13.9% gap on every dollar of revenue. On growth, MANNKIND CORP posted the faster year-over-year revenue change (45.8% vs 7.8%). ARDELYX, INC. produced more free cash flow last quarter ($20.6M vs $-10.0M). Over the past eight quarters, ARDELYX, INC.'s revenue compounded faster (64.9% CAGR vs 30.0%).
Ardelyx, Inc. is a commercial-stage biopharmaceutical firm developing and commercializing innovative therapies for gastrointestinal, cardiorenal and metabolic diseases with high unmet medical needs. Its lead product is approved in the US for irritable bowel syndrome with constipation, and it holds a robust pipeline of early and late-stage drug candidates.
MannKind Corporation is a biopharmaceutical company focusing on the discovery, development, and commercialization of therapeutic products for diseases such as diabetes and pulmonary arterial hypertension. Based in Danbury, Connecticut, the company was founded in February 1991.
ARDX vs MNKD — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $125.2M | $112.0M |
| Net Profit | $-407.0K | $-15.9M |
| Gross Margin | 91.3% | 87.6% |
| Operating Margin | 4.1% | -6.9% |
| Net Margin | -0.3% | -14.2% |
| Revenue YoY | 7.8% | 45.8% |
| Net Profit YoY | -108.8% | -314.9% |
| EPS (diluted) | $-0.01 | $-0.05 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $125.2M | $112.0M | ||
| Q3 25 | $110.3M | $82.1M | ||
| Q2 25 | $97.7M | $76.5M | ||
| Q1 25 | $74.1M | $78.4M | ||
| Q4 24 | $116.1M | $76.8M | ||
| Q3 24 | $98.2M | $70.1M | ||
| Q2 24 | $73.2M | $72.4M | ||
| Q1 24 | $46.0M | $66.3M |
| Q4 25 | $-407.0K | $-15.9M | ||
| Q3 25 | $-969.0K | $8.0M | ||
| Q2 25 | $-19.1M | $668.0K | ||
| Q1 25 | $-41.1M | $13.2M | ||
| Q4 24 | $4.6M | $7.4M | ||
| Q3 24 | $-809.0K | $11.6M | ||
| Q2 24 | $-16.5M | $-2.0M | ||
| Q1 24 | $-26.5M | $10.6M |
| Q4 25 | 91.3% | 87.6% | ||
| Q3 25 | 96.4% | 94.5% | ||
| Q2 25 | 87.3% | 94.0% | ||
| Q1 25 | 83.4% | 95.2% | ||
| Q4 24 | 84.3% | 93.7% | ||
| Q3 24 | 84.0% | 95.4% | ||
| Q2 24 | 87.1% | 92.3% | ||
| Q1 24 | 84.5% | 94.2% |
| Q4 25 | 4.1% | -6.9% | ||
| Q3 25 | 4.2% | 23.0% | ||
| Q2 25 | -14.7% | 6.9% | ||
| Q1 25 | -49.0% | 28.5% | ||
| Q4 24 | 7.0% | 34.5% | ||
| Q3 24 | 2.3% | 18.2% | ||
| Q2 24 | -18.6% | 22.9% | ||
| Q1 24 | -53.6% | 25.2% |
| Q4 25 | -0.3% | -14.2% | ||
| Q3 25 | -0.9% | 9.7% | ||
| Q2 25 | -19.5% | 0.9% | ||
| Q1 25 | -55.5% | 16.8% | ||
| Q4 24 | 4.0% | 9.7% | ||
| Q3 24 | -0.8% | 16.5% | ||
| Q2 24 | -22.5% | -2.8% | ||
| Q1 24 | -57.6% | 16.0% |
| Q4 25 | $-0.01 | $-0.05 | ||
| Q3 25 | $0.00 | $0.03 | ||
| Q2 25 | $-0.08 | $0.00 | ||
| Q1 25 | $-0.17 | $0.04 | ||
| Q4 24 | $0.01 | $0.03 | ||
| Q3 24 | $0.00 | $0.04 | ||
| Q2 24 | $-0.07 | $-0.01 | ||
| Q1 24 | $-0.11 | $0.04 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $68.0M | $171.3M |
| Total DebtLower is stronger | $202.8M | $354.6M |
| Stockholders' EquityBook value | $166.9M | $-51.0M |
| Total Assets | $501.6M | $792.2M |
| Debt / EquityLower = less leverage | 1.21× | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $68.0M | $171.3M | ||
| Q3 25 | $42.7M | $260.0M | ||
| Q2 25 | $90.0M | $179.0M | ||
| Q1 25 | $30.8M | $181.5M | ||
| Q4 24 | $64.9M | $197.3M | ||
| Q3 24 | $47.4M | $251.6M | ||
| Q2 24 | $41.9M | $247.8M | ||
| Q1 24 | $36.1M | $300.7M |
| Q4 25 | $202.8M | $354.6M | ||
| Q3 25 | $202.1M | $109.7M | ||
| Q2 25 | $201.4M | $36.2M | ||
| Q1 25 | $151.3M | $36.1M | ||
| Q4 24 | $150.9M | $36.1M | ||
| Q3 24 | $100.7M | $227.9M | ||
| Q2 24 | $100.2M | $227.6M | ||
| Q1 24 | $99.8M | $264.1M |
| Q4 25 | $166.9M | $-51.0M | ||
| Q3 25 | $154.3M | $-44.6M | ||
| Q2 25 | $139.5M | $-55.0M | ||
| Q1 25 | $145.7M | $-58.6M | ||
| Q4 24 | $173.3M | $-78.8M | ||
| Q3 24 | $158.3M | $-209.9M | ||
| Q2 24 | $147.0M | $-225.8M | ||
| Q1 24 | $150.9M | $-230.0M |
| Q4 25 | $501.6M | $792.2M | ||
| Q3 25 | $486.2M | $494.6M | ||
| Q2 25 | $466.8M | $411.7M | ||
| Q1 25 | $410.2M | $410.1M | ||
| Q4 24 | $435.8M | $393.8M | ||
| Q3 24 | $367.9M | $464.2M | ||
| Q2 24 | $343.5M | $443.8M | ||
| Q1 24 | $342.4M | $480.9M |
| Q4 25 | 1.21× | — | ||
| Q3 25 | 1.31× | — | ||
| Q2 25 | 1.44× | — | ||
| Q1 25 | 1.04× | — | ||
| Q4 24 | 0.87× | — | ||
| Q3 24 | 0.64× | — | ||
| Q2 24 | 0.68× | — | ||
| Q1 24 | 0.66× | — |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $21.0M | $-8.0M |
| Free Cash FlowOCF − Capex | $20.6M | $-10.0M |
| FCF MarginFCF / Revenue | 16.4% | -8.9% |
| Capex IntensityCapex / Revenue | 0.3% | 1.8% |
| Cash ConversionOCF / Net Profit | — | — |
| TTM Free Cash FlowTrailing 4 quarters | $-44.0M | $13.7M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $21.0M | $-8.0M | ||
| Q3 25 | $365.0K | $23.6M | ||
| Q2 25 | $-25.3M | $8.9M | ||
| Q1 25 | $-38.5M | $-6.4M | ||
| Q4 24 | $9.8M | $22.6M | ||
| Q3 24 | $501.0K | $9.3M | ||
| Q2 24 | $-19.4M | $3.8M | ||
| Q1 24 | $-35.7M | $6.7M |
| Q4 25 | $20.6M | $-10.0M | ||
| Q3 25 | $209.0K | $22.5M | ||
| Q2 25 | $-26.0M | $7.8M | ||
| Q1 25 | $-38.8M | $-6.7M | ||
| Q4 24 | $9.2M | $19.7M | ||
| Q3 24 | $364.0K | $7.9M | ||
| Q2 24 | $-19.5M | $861.0K | ||
| Q1 24 | $-35.9M | $4.3M |
| Q4 25 | 16.4% | -8.9% | ||
| Q3 25 | 0.2% | 27.4% | ||
| Q2 25 | -26.6% | 10.2% | ||
| Q1 25 | -52.3% | -8.6% | ||
| Q4 24 | 7.9% | 25.7% | ||
| Q3 24 | 0.4% | 11.3% | ||
| Q2 24 | -26.7% | 1.2% | ||
| Q1 24 | -77.9% | 6.5% |
| Q4 25 | 0.3% | 1.8% | ||
| Q3 25 | 0.1% | 1.4% | ||
| Q2 25 | 0.7% | 1.5% | ||
| Q1 25 | 0.4% | 0.4% | ||
| Q4 24 | 0.5% | 3.8% | ||
| Q3 24 | 0.1% | 2.0% | ||
| Q2 24 | 0.2% | 4.1% | ||
| Q1 24 | 0.3% | 3.6% |
| Q4 25 | — | — | ||
| Q3 25 | — | 2.96× | ||
| Q2 25 | — | 13.40× | ||
| Q1 25 | — | -0.48× | ||
| Q4 24 | 2.11× | 3.05× | ||
| Q3 24 | — | 0.81× | ||
| Q2 24 | — | — | ||
| Q1 24 | — | 0.63× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
ARDX
| Product IBSRELA | $86.6M | 69% |
| Product XPHOZAH | $27.8M | 22% |
| Other | $10.8M | 9% |
| Non Cash Royalty Related To Sale Of Future Royalties | $1.4M | 1% |
MNKD
| Products | $50.4M | 45% |
| Royalty | $33.6M | 30% |
| Afrezza | $22.9M | 20% |
| V Go | $4.3M | 4% |
