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Side-by-side financial comparison of ARVINAS, INC. (ARVN) and IRONWOOD PHARMACEUTICALS INC (IRWD). Click either name above to swap in a different company.
IRONWOOD PHARMACEUTICALS INC is the larger business by last-quarter revenue ($47.7M vs $41.9M, roughly 1.1× ARVINAS, INC.). IRONWOOD PHARMACEUTICALS INC runs the higher net margin — -4.8% vs -83.8%, a 79.0% gap on every dollar of revenue. On growth, IRONWOOD PHARMACEUTICALS INC posted the faster year-over-year revenue change (-47.3% vs -59.1%). IRONWOOD PHARMACEUTICALS INC produced more free cash flow last quarter ($74.6M vs $-59.2M). Over the past eight quarters, ARVINAS, INC.'s revenue compounded faster (10.0% CAGR vs -20.2%).
Arvinas, Inc. is a clinical-stage biotechnology company focused on developing targeted protein degradation therapies, including PROTAC molecules, to treat cancer and rare diseases. It operates primarily in the U.S. and global biopharma markets, advancing multiple pipeline candidates through clinical trials to address unmet medical needs.
Ironwood Pharmaceuticals, Inc. is a publicly traded pharmaceutical company. It was originally called Microbia, Inc.
ARVN vs IRWD — Head-to-Head
Income Statement — Q3 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $41.9M | $47.7M |
| Net Profit | $-35.1M | $-2.3M |
| Gross Margin | — | — |
| Operating Margin | -104.5% | 14.3% |
| Net Margin | -83.8% | -4.8% |
| Revenue YoY | -59.1% | -47.3% |
| Net Profit YoY | 28.7% | -200.9% |
| EPS (diluted) | $-0.48 | $0.01 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | — | $47.7M | ||
| Q3 25 | $41.9M | $122.1M | ||
| Q2 25 | — | $85.2M | ||
| Q1 25 | $188.8M | $41.1M | ||
| Q4 24 | $59.2M | $90.5M | ||
| Q3 24 | $102.4M | $91.6M | ||
| Q2 24 | $76.5M | $94.4M | ||
| Q1 24 | $25.3M | $74.9M |
| Q4 25 | — | $-2.3M | ||
| Q3 25 | $-35.1M | $40.1M | ||
| Q2 25 | — | $23.6M | ||
| Q1 25 | $82.9M | $-37.4M | ||
| Q4 24 | $-45.1M | $2.3M | ||
| Q3 24 | $-49.2M | $3.6M | ||
| Q2 24 | $-35.2M | $-860.0K | ||
| Q1 24 | $-69.4M | $-4.2M |
| Q4 25 | — | 14.3% | ||
| Q3 25 | -104.5% | 61.8% | ||
| Q2 25 | — | 53.2% | ||
| Q1 25 | 37.8% | -70.7% | ||
| Q4 24 | -98.1% | 34.8% | ||
| Q3 24 | -58.9% | 28.0% | ||
| Q2 24 | -63.4% | 26.5% | ||
| Q1 24 | -329.2% | 14.7% |
| Q4 25 | — | -4.8% | ||
| Q3 25 | -83.8% | 32.8% | ||
| Q2 25 | — | 27.7% | ||
| Q1 25 | 43.9% | -90.9% | ||
| Q4 24 | -76.2% | 2.5% | ||
| Q3 24 | -48.0% | 4.0% | ||
| Q2 24 | -46.0% | -0.9% | ||
| Q1 24 | -274.3% | -5.6% |
| Q4 25 | — | $0.01 | ||
| Q3 25 | $-0.48 | $0.23 | ||
| Q2 25 | — | $0.14 | ||
| Q1 25 | $1.14 | $-0.23 | ||
| Q4 24 | $-0.63 | $0.03 | ||
| Q3 24 | $-0.68 | $0.02 | ||
| Q2 24 | $-0.49 | $-0.01 | ||
| Q1 24 | $-0.97 | $-0.03 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $787.6M | $215.5M |
| Total DebtLower is stronger | $600.0K | — |
| Stockholders' EquityBook value | $564.4M | $-261.8M |
| Total Assets | $844.3M | $396.9M |
| Debt / EquityLower = less leverage | 0.00× | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | — | $215.5M | ||
| Q3 25 | $787.6M | $140.4M | ||
| Q2 25 | — | $92.9M | ||
| Q1 25 | $954.3M | $108.5M | ||
| Q4 24 | $1.0B | $88.6M | ||
| Q3 24 | $1.1B | $88.2M | ||
| Q2 24 | $1.2B | $105.5M | ||
| Q1 24 | $1.2B | $121.5M |
| Q4 25 | — | — | ||
| Q3 25 | $600.0K | $199.5M | ||
| Q2 25 | — | $199.3M | ||
| Q1 25 | $700.0K | $199.2M | ||
| Q4 24 | $800.0K | $199.0M | ||
| Q3 24 | $800.0K | $198.8M | ||
| Q2 24 | $900.0K | $198.6M | ||
| Q1 24 | $900.0K | $398.3M |
| Q4 25 | — | $-261.8M | ||
| Q3 25 | $564.4M | $-264.2M | ||
| Q2 25 | — | $-308.2M | ||
| Q1 25 | $660.1M | $-334.1M | ||
| Q4 24 | $561.7M | $-301.3M | ||
| Q3 24 | $586.0M | $-311.3M | ||
| Q2 24 | $600.2M | $-321.7M | ||
| Q1 24 | $609.7M | $-330.5M |
| Q4 25 | — | $396.9M | ||
| Q3 25 | $844.3M | $396.1M | ||
| Q2 25 | — | $342.9M | ||
| Q1 25 | $1.0B | $327.2M | ||
| Q4 24 | $1.1B | $350.9M | ||
| Q3 24 | $1.2B | $389.5M | ||
| Q2 24 | $1.3B | $395.6M | ||
| Q1 24 | $1.2B | $438.8M |
| Q4 25 | — | — | ||
| Q3 25 | 0.00× | — | ||
| Q2 25 | — | — | ||
| Q1 25 | 0.00× | — | ||
| Q4 24 | 0.00× | — | ||
| Q3 24 | 0.00× | — | ||
| Q2 24 | 0.00× | — | ||
| Q1 24 | 0.00× | — |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-59.1M | $74.6M |
| Free Cash FlowOCF − Capex | $-59.2M | $74.6M |
| FCF MarginFCF / Revenue | -141.3% | 156.3% |
| Capex IntensityCapex / Revenue | 0.2% | 0.0% |
| Cash ConversionOCF / Net Profit | — | — |
| TTM Free Cash FlowTrailing 4 quarters | $-361.6M | $127.0M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | — | $74.6M | ||
| Q3 25 | $-59.1M | $47.6M | ||
| Q2 25 | — | $-15.1M | ||
| Q1 25 | $-88.9M | $20.0M | ||
| Q4 24 | $-84.1M | $15.2M | ||
| Q3 24 | $-128.0M | $9.9M | ||
| Q2 24 | $50.3M | $33.5M | ||
| Q1 24 | $-97.5M | $45.0M |
| Q4 25 | — | $74.6M | ||
| Q3 25 | $-59.2M | $47.6M | ||
| Q2 25 | — | $-15.1M | ||
| Q1 25 | $-89.3M | $19.9M | ||
| Q4 24 | $-84.4M | — | ||
| Q3 24 | $-128.7M | $9.9M | ||
| Q2 24 | $49.6M | $33.4M | ||
| Q1 24 | $-97.6M | $44.9M |
| Q4 25 | — | 156.3% | ||
| Q3 25 | -141.3% | 39.0% | ||
| Q2 25 | — | -17.7% | ||
| Q1 25 | -47.3% | 48.4% | ||
| Q4 24 | -142.6% | — | ||
| Q3 24 | -125.7% | 10.8% | ||
| Q2 24 | 64.8% | 35.4% | ||
| Q1 24 | -385.8% | 60.0% |
| Q4 25 | — | 0.0% | ||
| Q3 25 | 0.2% | 0.0% | ||
| Q2 25 | — | 0.0% | ||
| Q1 25 | 0.2% | 0.1% | ||
| Q4 24 | 0.5% | 0.0% | ||
| Q3 24 | 0.7% | 0.0% | ||
| Q2 24 | 0.9% | 0.1% | ||
| Q1 24 | 0.4% | 0.1% |
| Q4 25 | — | — | ||
| Q3 25 | — | 1.19× | ||
| Q2 25 | — | -0.64× | ||
| Q1 25 | -1.07× | — | ||
| Q4 24 | — | 6.74× | ||
| Q3 24 | — | 2.71× | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
