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Side-by-side financial comparison of ARROWHEAD PHARMACEUTICALS, INC. (ARWR) and IDEAYA Biosciences, Inc. (IDYA). Click either name above to swap in a different company.

ARROWHEAD PHARMACEUTICALS, INC. is the larger business by last-quarter revenue ($264.0M vs $207.8M, roughly 1.3× IDEAYA Biosciences, Inc.). IDEAYA Biosciences, Inc. runs the higher net margin — 57.4% vs 11.7%, a 45.7% gap on every dollar of revenue. IDEAYA Biosciences, Inc. produced more free cash flow last quarter ($142.2M vs $11.3M).

Arrowhead Pharmaceuticals, Inc. is a publicly traded biopharmaceutical company based in Pasadena, California. Arrowhead's products in development act through RNA interference (RNAi) mechanisms of action. The company focuses on treatments for hepatitis B, liver disease associated with alpha 1-antitrypsin deficiency and cardiovascular disease.

IDEAYA Biosciences, Inc. is a clinical-stage biotechnology company focused on oncology, developing targeted therapies and synthetic lethality treatments for patients with genetically defined cancers. It advances a pipeline of candidates across multiple tumor types, partnering with industry stakeholders to accelerate global access to innovative cancer care solutions.

ARWR vs IDYA — Head-to-Head

Bigger by revenue
ARWR
ARWR
1.3× larger
ARWR
$264.0M
$207.8M
IDYA
Higher net margin
IDYA
IDYA
45.7% more per $
IDYA
57.4%
11.7%
ARWR
More free cash flow
IDYA
IDYA
$130.8M more FCF
IDYA
$142.2M
$11.3M
ARWR

Income Statement — Q1 FY2026 vs Q3 FY2025

Metric
ARWR
ARWR
IDYA
IDYA
Revenue
$264.0M
$207.8M
Net Profit
$30.8M
$119.2M
Gross Margin
Operating Margin
15.5%
52.2%
Net Margin
11.7%
57.4%
Revenue YoY
10461.3%
Net Profit YoY
117.8%
330.1%
EPS (diluted)
$0.22
$1.33

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ARWR
ARWR
IDYA
IDYA
Q4 25
$264.0M
Q3 25
$207.8M
Q3 24
$0
Q2 24
$0
Q1 24
$0
Q3 22
$29.7M
Net Profit
ARWR
ARWR
IDYA
IDYA
Q4 25
$30.8M
Q3 25
$119.2M
Q3 24
$-51.8M
Q2 24
$-52.8M
Q1 24
$-39.6M
Q3 22
$1.6M
Operating Margin
ARWR
ARWR
IDYA
IDYA
Q4 25
15.5%
Q3 25
52.2%
Q3 24
Q2 24
Q1 24
Q3 22
2.2%
Net Margin
ARWR
ARWR
IDYA
IDYA
Q4 25
11.7%
Q3 25
57.4%
Q3 24
Q2 24
Q1 24
Q3 22
5.4%
EPS (diluted)
ARWR
ARWR
IDYA
IDYA
Q4 25
$0.22
Q3 25
$1.33
Q3 24
$-0.60
Q2 24
$-0.68
Q1 24
$-0.53
Q3 22
$0.04

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ARWR
ARWR
IDYA
IDYA
Cash + ST InvestmentsLiquidity on hand
$715.0M
$786.9M
Total DebtLower is stronger
Stockholders' EquityBook value
$568.4M
$1.1B
Total Assets
$1.6B
$1.2B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ARWR
ARWR
IDYA
IDYA
Q4 25
$715.0M
Q3 25
$786.9M
Q3 24
$920.0M
Q2 24
$701.7M
Q1 24
$698.8M
Q3 22
$386.2M
Stockholders' Equity
ARWR
ARWR
IDYA
IDYA
Q4 25
$568.4M
Q3 25
$1.1B
Q3 24
$1.2B
Q2 24
$931.7M
Q1 24
$935.3M
Q3 22
$368.8M
Total Assets
ARWR
ARWR
IDYA
IDYA
Q4 25
$1.6B
Q3 25
$1.2B
Q3 24
$1.2B
Q2 24
$973.7M
Q1 24
$961.5M
Q3 22
$410.9M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ARWR
ARWR
IDYA
IDYA
Operating Cash FlowLast quarter
$13.5M
$142.2M
Free Cash FlowOCF − Capex
$11.3M
$142.2M
FCF MarginFCF / Revenue
4.3%
68.4%
Capex IntensityCapex / Revenue
0.8%
0.0%
Cash ConversionOCF / Net Profit
0.44×
1.19×
TTM Free Cash FlowTrailing 4 quarters
$13.5M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ARWR
ARWR
IDYA
IDYA
Q4 25
$13.5M
Q3 25
$142.2M
Q3 24
$-49.2M
Q2 24
$-32.9M
Q1 24
$-43.8M
Q3 22
$-24.2M
Free Cash Flow
ARWR
ARWR
IDYA
IDYA
Q4 25
$11.3M
Q3 25
$142.2M
Q3 24
$-49.7M
Q2 24
$-33.9M
Q1 24
$-45.1M
Q3 22
$-25.3M
FCF Margin
ARWR
ARWR
IDYA
IDYA
Q4 25
4.3%
Q3 25
68.4%
Q3 24
Q2 24
Q1 24
Q3 22
-85.1%
Capex Intensity
ARWR
ARWR
IDYA
IDYA
Q4 25
0.8%
Q3 25
0.0%
Q3 24
Q2 24
Q1 24
Q3 22
3.7%
Cash Conversion
ARWR
ARWR
IDYA
IDYA
Q4 25
0.44×
Q3 25
1.19×
Q3 24
Q2 24
Q1 24
Q3 22
-14.96×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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