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Side-by-side financial comparison of ASSEMBLY BIOSCIENCES, INC. (ASMB) and ASP Isotopes Inc. (ASPI). Click either name above to swap in a different company.

ASP Isotopes Inc. is the larger business by last-quarter revenue ($16.7M vs $10.8M, roughly 1.5× ASSEMBLY BIOSCIENCES, INC.). On growth, ASP Isotopes Inc. posted the faster year-over-year revenue change (1295.7% vs 57.6%). ASSEMBLY BIOSCIENCES, INC. produced more free cash flow last quarter ($-15.2M vs $-47.4M).

Pacific Biosciences of California, Inc. is an American biotechnology company founded in 2004 that develops and manufactures systems for gene sequencing and some novel real time biological observation. PacBio has two principal sequencing platforms: single-molecule real-time sequencing (SMRT), based on the properties of zero-mode waveguides and sequencing by binding (SBB) chemistry, which uses native nucleotides and scarless incorporation for DNA binding and extension.

ASP Isotopes Inc. is a specialty materials firm focused on developing and producing high-purity custom isotopes. Its products serve key sectors including nuclear medicine, targeted cancer therapies, advanced energy, and industrial research, with customers across North America, Europe and Asia Pacific.

ASMB vs ASPI — Head-to-Head

Bigger by revenue
ASPI
ASPI
1.5× larger
ASPI
$16.7M
$10.8M
ASMB
Growing faster (revenue YoY)
ASPI
ASPI
+1238.1% gap
ASPI
1295.7%
57.6%
ASMB
More free cash flow
ASMB
ASMB
$32.3M more FCF
ASMB
$-15.2M
$-47.4M
ASPI

Income Statement — Q3 FY2025 vs Q4 FY2025

Metric
ASMB
ASMB
ASPI
ASPI
Revenue
$10.8M
$16.7M
Net Profit
$-9.2M
Gross Margin
12.5%
Operating Margin
-100.9%
Net Margin
-85.2%
Revenue YoY
57.6%
1295.7%
Net Profit YoY
4.3%
-586.8%
EPS (diluted)
$-0.72

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ASMB
ASMB
ASPI
ASPI
Q4 25
$16.7M
Q3 25
$10.8M
$4.9M
Q2 25
$9.6M
Q1 25
$9.4M
Q4 24
$7.4M
Q3 24
$6.8M
Q2 24
$8.5M
Q1 24
$5.8M
Net Profit
ASMB
ASMB
ASPI
ASPI
Q4 25
Q3 25
$-9.2M
$-12.9M
Q2 25
$-10.2M
Q1 25
$-8.8M
Q4 24
Q3 24
$-9.6M
Q2 24
$-11.2M
Q1 24
$-9.1M
Gross Margin
ASMB
ASMB
ASPI
ASPI
Q4 25
12.5%
Q3 25
8.7%
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
Operating Margin
ASMB
ASMB
ASPI
ASPI
Q4 25
Q3 25
-100.9%
-306.1%
Q2 25
-115.2%
Q1 25
-105.5%
Q4 24
Q3 24
-160.1%
Q2 24
-143.0%
Q1 24
-185.5%
Net Margin
ASMB
ASMB
ASPI
ASPI
Q4 25
Q3 25
-85.2%
-263.7%
Q2 25
-105.9%
Q1 25
-93.6%
Q4 24
Q3 24
-140.4%
Q2 24
-130.7%
Q1 24
-156.9%
EPS (diluted)
ASMB
ASMB
ASPI
ASPI
Q4 25
Q3 25
$-0.72
$-0.15
Q2 25
$-1.33
Q1 25
$-1.17
Q4 24
Q3 24
$-1.51
Q2 24
$-1.98
Q1 24
$-1.66

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ASMB
ASMB
ASPI
ASPI
Cash + ST InvestmentsLiquidity on hand
$22.5M
$333.3M
Total DebtLower is stronger
$14.4M
Stockholders' EquityBook value
$182.7M
$204.2M
Total Assets
$240.0M
$498.0M
Debt / EquityLower = less leverage
0.07×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ASMB
ASMB
ASPI
ASPI
Q4 25
$333.3M
Q3 25
$22.5M
$113.9M
Q2 25
$24.0M
Q1 25
$23.4M
Q4 24
$38.3M
Q3 24
$28.5M
Q2 24
$19.2M
Q1 24
$18.7M
Total Debt
ASMB
ASMB
ASPI
ASPI
Q4 25
$14.4M
Q3 25
$13.9M
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
Stockholders' Equity
ASMB
ASMB
ASPI
ASPI
Q4 25
$204.2M
Q3 25
$182.7M
$74.1M
Q2 25
$18.1M
Q1 25
$27.1M
Q4 24
$33.4M
Q3 24
$26.0M
Q2 24
$34.7M
Q1 24
$32.6M
Total Assets
ASMB
ASMB
ASPI
ASPI
Q4 25
$498.0M
Q3 25
$240.0M
$225.9M
Q2 25
$80.8M
Q1 25
$99.0M
Q4 24
$119.2M
Q3 24
$100.3M
Q2 24
$115.3M
Q1 24
$119.9M
Debt / Equity
ASMB
ASMB
ASPI
ASPI
Q4 25
0.07×
Q3 25
0.19×
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ASMB
ASMB
ASPI
ASPI
Operating Cash FlowLast quarter
$-15.1M
$-37.8M
Free Cash FlowOCF − Capex
$-15.2M
$-47.4M
FCF MarginFCF / Revenue
-140.7%
-284.7%
Capex IntensityCapex / Revenue
0.4%
57.9%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ASMB
ASMB
ASPI
ASPI
Q4 25
$-37.8M
Q3 25
$-15.1M
$-8.9M
Q2 25
$-16.8M
Q1 25
$-23.4M
Q4 24
$-51.1M
Q3 24
$-15.2M
Q2 24
$-17.1M
Q1 24
$-18.4M
Free Cash Flow
ASMB
ASMB
ASPI
ASPI
Q4 25
$-47.4M
Q3 25
$-15.2M
$-12.0M
Q2 25
Q1 25
Q4 24
$-51.1M
Q3 24
Q2 24
$-17.1M
Q1 24
$-18.4M
FCF Margin
ASMB
ASMB
ASPI
ASPI
Q4 25
-284.7%
Q3 25
-140.7%
-245.5%
Q2 25
Q1 25
Q4 24
-695.2%
Q3 24
Q2 24
-200.6%
Q1 24
-317.7%
Capex Intensity
ASMB
ASMB
ASPI
ASPI
Q4 25
57.9%
Q3 25
0.4%
64.4%
Q2 25
0.0%
Q1 25
0.0%
Q4 24
0.4%
Q3 24
0.0%
Q2 24
0.2%
Q1 24
0.2%

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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