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Side-by-side financial comparison of ASSEMBLY BIOSCIENCES, INC. (ASMB) and ECB Bancorp, Inc. (ECBK). Click either name above to swap in a different company.

ASSEMBLY BIOSCIENCES, INC. is the larger business by last-quarter revenue ($10.8M vs $9.5M, roughly 1.1× ECB Bancorp, Inc.). ECB Bancorp, Inc. runs the higher net margin — 27.3% vs -85.2%, a 112.5% gap on every dollar of revenue. On growth, ASSEMBLY BIOSCIENCES, INC. posted the faster year-over-year revenue change (57.6% vs 33.8%). ECB Bancorp, Inc. produced more free cash flow last quarter ($9.0M vs $-15.2M).

Pacific Biosciences of California, Inc. is an American biotechnology company founded in 2004 that develops and manufactures systems for gene sequencing and some novel real time biological observation. PacBio has two principal sequencing platforms: single-molecule real-time sequencing (SMRT), based on the properties of zero-mode waveguides and sequencing by binding (SBB) chemistry, which uses native nucleotides and scarless incorporation for DNA binding and extension.

ECB Bancorp, Inc. (MD) is a US-based bank holding company. It offers a full suite of retail and commercial banking products including deposit accounts, consumer loans, commercial financing and wealth management solutions, primarily serving individuals and small-to-mid enterprises across local markets in Maryland.

ASMB vs ECBK — Head-to-Head

Bigger by revenue
ASMB
ASMB
1.1× larger
ASMB
$10.8M
$9.5M
ECBK
Growing faster (revenue YoY)
ASMB
ASMB
+23.8% gap
ASMB
57.6%
33.8%
ECBK
Higher net margin
ECBK
ECBK
112.5% more per $
ECBK
27.3%
-85.2%
ASMB
More free cash flow
ECBK
ECBK
$24.2M more FCF
ECBK
$9.0M
$-15.2M
ASMB

Income Statement — Q3 FY2025 vs Q4 FY2025

Metric
ASMB
ASMB
ECBK
ECBK
Revenue
$10.8M
$9.5M
Net Profit
$-9.2M
$2.6M
Gross Margin
Operating Margin
-100.9%
36.7%
Net Margin
-85.2%
27.3%
Revenue YoY
57.6%
33.8%
Net Profit YoY
4.3%
79.5%
EPS (diluted)
$-0.72
$0.32

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ASMB
ASMB
ECBK
ECBK
Q4 25
$9.5M
Q3 25
$10.8M
$8.8M
Q2 25
$9.6M
$8.0M
Q1 25
$9.4M
$6.9M
Q4 24
$7.4M
$7.1M
Q3 24
$6.8M
$6.6M
Q2 24
$8.5M
$6.3M
Q1 24
$5.8M
$6.2M
Net Profit
ASMB
ASMB
ECBK
ECBK
Q4 25
$2.6M
Q3 25
$-9.2M
$2.4M
Q2 25
$-10.2M
$1.4M
Q1 25
$-8.8M
$1.3M
Q4 24
$1.4M
Q3 24
$-9.6M
$1.1M
Q2 24
$-11.2M
$791.0K
Q1 24
$-9.1M
$621.0K
Operating Margin
ASMB
ASMB
ECBK
ECBK
Q4 25
36.7%
Q3 25
-100.9%
37.0%
Q2 25
-115.2%
23.9%
Q1 25
-105.5%
24.9%
Q4 24
27.3%
Q3 24
-160.1%
23.3%
Q2 24
-143.0%
16.9%
Q1 24
-185.5%
13.4%
Net Margin
ASMB
ASMB
ECBK
ECBK
Q4 25
27.3%
Q3 25
-85.2%
27.7%
Q2 25
-105.9%
18.0%
Q1 25
-93.6%
18.7%
Q4 24
20.3%
Q3 24
-140.4%
17.2%
Q2 24
-130.7%
12.6%
Q1 24
-156.9%
10.0%
EPS (diluted)
ASMB
ASMB
ECBK
ECBK
Q4 25
$0.32
Q3 25
$-0.72
$0.29
Q2 25
$-1.33
$0.17
Q1 25
$-1.17
$0.16
Q4 24
$0.18
Q3 24
$-1.51
$0.14
Q2 24
$-1.98
$0.09
Q1 24
$-1.66
$0.07

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ASMB
ASMB
ECBK
ECBK
Cash + ST InvestmentsLiquidity on hand
$22.5M
$82.8M
Total DebtLower is stronger
Stockholders' EquityBook value
$182.7M
$171.9M
Total Assets
$240.0M
$1.6B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ASMB
ASMB
ECBK
ECBK
Q4 25
$82.8M
Q3 25
$22.5M
$201.9M
Q2 25
$24.0M
$191.0M
Q1 25
$23.4M
$143.7M
Q4 24
$38.3M
$309.4M
Q3 24
$28.5M
$114.8M
Q2 24
$19.2M
$108.7M
Q1 24
$18.7M
$109.8M
Stockholders' Equity
ASMB
ASMB
ECBK
ECBK
Q4 25
$171.9M
Q3 25
$182.7M
$169.3M
Q2 25
$18.1M
$168.3M
Q1 25
$27.1M
$168.6M
Q4 24
$33.4M
$168.3M
Q3 24
$26.0M
$166.0M
Q2 24
$34.7M
$166.5M
Q1 24
$32.6M
$165.8M
Total Assets
ASMB
ASMB
ECBK
ECBK
Q4 25
$1.6B
Q3 25
$240.0M
$1.6B
Q2 25
$80.8M
$1.5B
Q1 25
$99.0M
$1.5B
Q4 24
$119.2M
$1.4B
Q3 24
$100.3M
$1.4B
Q2 24
$115.3M
$1.3B
Q1 24
$119.9M
$1.3B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ASMB
ASMB
ECBK
ECBK
Operating Cash FlowLast quarter
$-15.1M
$9.2M
Free Cash FlowOCF − Capex
$-15.2M
$9.0M
FCF MarginFCF / Revenue
-140.7%
94.7%
Capex IntensityCapex / Revenue
0.4%
2.2%
Cash ConversionOCF / Net Profit
3.55×
TTM Free Cash FlowTrailing 4 quarters
$14.2M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ASMB
ASMB
ECBK
ECBK
Q4 25
$9.2M
Q3 25
$-15.1M
$4.0M
Q2 25
$-16.8M
$1.9M
Q1 25
$-23.4M
$-631.0K
Q4 24
$-51.1M
$6.2M
Q3 24
$-15.2M
$861.0K
Q2 24
$-17.1M
$1.4M
Q1 24
$-18.4M
$-429.0K
Free Cash Flow
ASMB
ASMB
ECBK
ECBK
Q4 25
$9.0M
Q3 25
$-15.2M
$4.0M
Q2 25
$1.8M
Q1 25
$-649.0K
Q4 24
$-51.1M
$6.2M
Q3 24
Q2 24
$-17.1M
$1.3M
Q1 24
$-18.4M
$-449.0K
FCF Margin
ASMB
ASMB
ECBK
ECBK
Q4 25
94.7%
Q3 25
-140.7%
44.9%
Q2 25
23.0%
Q1 25
-9.4%
Q4 24
-695.2%
86.8%
Q3 24
Q2 24
-200.6%
21.4%
Q1 24
-317.7%
-7.2%
Capex Intensity
ASMB
ASMB
ECBK
ECBK
Q4 25
2.2%
Q3 25
0.4%
0.8%
Q2 25
0.0%
0.6%
Q1 25
0.0%
0.3%
Q4 24
0.4%
0.8%
Q3 24
0.0%
0.0%
Q2 24
0.2%
0.6%
Q1 24
0.2%
0.3%
Cash Conversion
ASMB
ASMB
ECBK
ECBK
Q4 25
3.55×
Q3 25
1.65×
Q2 25
1.32×
Q1 25
-0.49×
Q4 24
4.31×
Q3 24
0.76×
Q2 24
1.75×
Q1 24
-0.69×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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