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Side-by-side financial comparison of Ascendis Pharma A/S (ASND) and Yatsen Holding Ltd (YSG). Click either name above to swap in a different company.

Ascendis Pharma A/S is the larger business by last-quarter revenue ($267.3M vs $164.2M, roughly 1.6× Yatsen Holding Ltd). Over the past eight quarters, Ascendis Pharma A/S's revenue compounded faster (60.7% CAGR vs 24.5%).

Growth hormone therapy refers to the use of growth hormone (GH) as a prescription medication—it is one form of hormone therapy. Growth hormone is a peptide hormone secreted by the pituitary gland that stimulates growth and cell reproduction. In the past, growth hormone was extracted from human pituitary glands. Growth hormone is now produced by recombinant DNA technology and is prescribed for a variety of reasons. GH therapy has been a focus of social and ethical controversies for 50 years.

Yatsen Holding Ltd is a leading China-based beauty and personal care group. It develops and sells cosmetics, skincare products and fragrances under brands including Perfect Diary, Little Ondine and Abby's Choice, with core markets in mainland China, Southeast Asia, targeting Gen Z and young adult consumers.

ASND vs YSG — Head-to-Head

Bigger by revenue
ASND
ASND
1.6× larger
ASND
$267.3M
$164.2M
YSG
Faster 2-yr revenue CAGR
ASND
ASND
Annualised
ASND
60.7%
24.5%
YSG

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
ASND
ASND
YSG
YSG
Revenue
$267.3M
$164.2M
Net Profit
$-776.5K
Gross Margin
90.5%
77.8%
Operating Margin
-34.0%
Net Margin
-0.5%
Revenue YoY
42.3%
Net Profit YoY
EPS (diluted)

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ASND
ASND
YSG
YSG
Q4 25
$267.3M
$164.2M
Q3 25
$230.7M
$95.1M
Q2 25
$170.7M
$110.9M
Q1 25
$109.0M
$106.6M
Q4 24
$187.8M
$147.0M
Q3 24
$62.5M
$102.3M
Q2 24
$38.9M
$118.1M
Q1 24
$103.6M
$106.0M
Net Profit
ASND
ASND
YSG
YSG
Q4 25
$-776.5K
Q3 25
$-65.9M
$-17.0M
Q2 25
$-42.0M
$-11.9M
Q1 25
$-102.2M
$-17.2M
Q4 24
$-67.7M
Q3 24
$-107.1M
$-28.2M
Q2 24
$-118.1M
$-14.9M
Q1 24
$-141.5M
$7.0M
Gross Margin
ASND
ASND
YSG
YSG
Q4 25
90.5%
77.8%
Q3 25
89.5%
75.9%
Q2 25
80.1%
76.7%
Q1 25
82.6%
77.7%
Q4 24
91.9%
73.7%
Q3 24
80.6%
71.4%
Q2 24
68.2%
74.7%
Q1 24
92.1%
74.3%
Operating Margin
ASND
ASND
YSG
YSG
Q4 25
-34.0%
Q3 25
5.1%
-20.9%
Q2 25
-33.5%
-17.0%
Q1 25
-103.2%
-20.4%
Q4 24
-50.3%
Q3 24
-167.3%
-32.2%
Q2 24
-370.2%
-15.7%
Q1 24
-51.2%
-0.9%
Net Margin
ASND
ASND
YSG
YSG
Q4 25
-0.5%
Q3 25
-28.5%
-17.9%
Q2 25
-24.6%
-10.8%
Q1 25
-93.7%
-16.1%
Q4 24
-46.1%
Q3 24
-171.5%
-27.6%
Q2 24
-303.9%
-12.6%
Q1 24
-136.6%
6.6%

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ASND
ASND
YSG
YSG
Cash + ST InvestmentsLiquidity on hand
$665.3M
$109.4M
Total DebtLower is stronger
Stockholders' EquityBook value
$-175.8M
$428.9M
Total Assets
$1.4B
$550.1M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ASND
ASND
YSG
YSG
Q4 25
$665.3M
$109.4M
Q3 25
$582.2M
$97.0M
Q2 25
$533.6M
$133.1M
Q1 25
$559.4M
$92.3M
Q4 24
$604.3M
$112.0M
Q3 24
$675.6M
$71.7M
Q2 24
$279.4M
$109.6M
Q1 24
$345.9M
$179.9M
Stockholders' Equity
ASND
ASND
YSG
YSG
Q4 25
$-175.8M
$428.9M
Q3 25
$-188.0M
$423.1M
Q2 25
$-202.6M
$431.5M
Q1 25
$-205.0M
$422.2M
Q4 24
$-114.2M
$418.1M
Q3 24
$-105.1M
$516.0M
Q2 24
$-346.8M
$519.4M
Q1 24
$-257.2M
$551.6M
Total Assets
ASND
ASND
YSG
YSG
Q4 25
$1.4B
$550.1M
Q3 25
$1.2B
$564.8M
Q2 25
$1.2B
$564.4M
Q1 25
$1.1B
$534.3M
Q4 24
$1.3B
$544.0M
Q3 24
$1.2B
$635.6M
Q2 24
$819.0M
$635.8M
Q1 24
$866.7M
$662.1M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ASND
ASND
YSG
YSG
Operating Cash FlowLast quarter
$58.2M
Free Cash FlowOCF − Capex
FCF MarginFCF / Revenue
Capex IntensityCapex / Revenue
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ASND
ASND
YSG
YSG
Q4 25
$58.2M
Q3 25
Q2 25
Q1 25
$-15.5M
Q4 24
$-330.7M
Q3 24
Q2 24
Q1 24
$-109.7M

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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