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Side-by-side financial comparison of ASP Isotopes Inc. (ASPI) and ClearPoint Neuro, Inc. (CLPT). Click either name above to swap in a different company.

ASP Isotopes Inc. is the larger business by last-quarter revenue ($16.7M vs $10.4M, roughly 1.6× ClearPoint Neuro, Inc.). On growth, ASP Isotopes Inc. posted the faster year-over-year revenue change (1295.7% vs 34.0%). ClearPoint Neuro, Inc. produced more free cash flow last quarter ($-12.1M vs $-47.4M).

ASP Isotopes Inc. is a specialty materials firm focused on developing and producing high-purity custom isotopes. Its products serve key sectors including nuclear medicine, targeted cancer therapies, advanced energy, and industrial research, with customers across North America, Europe and Asia Pacific.

ClearPoint Neuro, Inc. is a medical technology firm specializing in precision neurology solutions. It develops and commercializes intraoperative navigation, targeting and delivery systems for minimally invasive brain surgeries, neurological disorder treatments, and CNS therapy development for global clinical and biopharmaceutical partners.

ASPI vs CLPT — Head-to-Head

Bigger by revenue
ASPI
ASPI
1.6× larger
ASPI
$16.7M
$10.4M
CLPT
Growing faster (revenue YoY)
ASPI
ASPI
+1261.7% gap
ASPI
1295.7%
34.0%
CLPT
More free cash flow
CLPT
CLPT
$35.3M more FCF
CLPT
$-12.1M
$-47.4M
ASPI

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
ASPI
ASPI
CLPT
CLPT
Revenue
$16.7M
$10.4M
Net Profit
Gross Margin
12.5%
61.5%
Operating Margin
-67.7%
Net Margin
Revenue YoY
1295.7%
34.0%
Net Profit YoY
-586.8%
EPS (diluted)
$-0.26

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ASPI
ASPI
CLPT
CLPT
Q4 25
$16.7M
$10.4M
Q3 25
$4.9M
$8.9M
Q2 25
$9.2M
Q1 25
$8.5M
Q4 24
$7.8M
Q3 24
$8.1M
Q2 24
$7.9M
Q1 24
$7.6M
Net Profit
ASPI
ASPI
CLPT
CLPT
Q4 25
Q3 25
$-12.9M
$-5.9M
Q2 25
$-5.8M
Q1 25
$-6.0M
Q4 24
Q3 24
$-5.0M
Q2 24
$-4.4M
Q1 24
$-4.1M
Gross Margin
ASPI
ASPI
CLPT
CLPT
Q4 25
12.5%
61.5%
Q3 25
8.7%
63.2%
Q2 25
60.3%
Q1 25
60.5%
Q4 24
61.3%
Q3 24
59.7%
Q2 24
63.5%
Q1 24
59.2%
Operating Margin
ASPI
ASPI
CLPT
CLPT
Q4 25
-67.7%
Q3 25
-306.1%
-59.5%
Q2 25
-61.6%
Q1 25
-72.6%
Q4 24
-72.5%
Q3 24
-63.5%
Q2 24
-60.1%
Q1 24
-55.2%
Net Margin
ASPI
ASPI
CLPT
CLPT
Q4 25
Q3 25
-263.7%
-66.5%
Q2 25
-63.3%
Q1 25
-71.0%
Q4 24
Q3 24
-61.2%
Q2 24
-56.1%
Q1 24
-54.3%
EPS (diluted)
ASPI
ASPI
CLPT
CLPT
Q4 25
$-0.26
Q3 25
$-0.15
$-0.21
Q2 25
$-0.21
Q1 25
$-0.22
Q4 24
$-0.20
Q3 24
$-0.18
Q2 24
$-0.16
Q1 24
$-0.16

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ASPI
ASPI
CLPT
CLPT
Cash + ST InvestmentsLiquidity on hand
$333.3M
$45.9M
Total DebtLower is stronger
$14.4M
$49.1M
Stockholders' EquityBook value
$204.2M
$28.0M
Total Assets
$498.0M
$97.7M
Debt / EquityLower = less leverage
0.07×
1.75×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ASPI
ASPI
CLPT
CLPT
Q4 25
$333.3M
$45.9M
Q3 25
$113.9M
$38.2M
Q2 25
$41.5M
Q1 25
$12.4M
Q4 24
$20.1M
Q3 24
$21.6M
Q2 24
$32.8M
Q1 24
$35.4M
Total Debt
ASPI
ASPI
CLPT
CLPT
Q4 25
$14.4M
$49.1M
Q3 25
$13.9M
$29.2M
Q2 25
$28.8M
Q1 25
Q4 24
Q3 24
Q2 24
$10.0M
Q1 24
$10.0M
Stockholders' Equity
ASPI
ASPI
CLPT
CLPT
Q4 25
$204.2M
$28.0M
Q3 25
$74.1M
$15.9M
Q2 25
$19.7M
Q1 25
$20.0M
Q4 24
$25.4M
Q3 24
$29.0M
Q2 24
$32.1M
Q1 24
$34.6M
Total Assets
ASPI
ASPI
CLPT
CLPT
Q4 25
$498.0M
$97.7M
Q3 25
$225.9M
$60.4M
Q2 25
$62.9M
Q1 25
$30.1M
Q4 24
$39.2M
Q3 24
$40.2M
Q2 24
$52.6M
Q1 24
$53.6M
Debt / Equity
ASPI
ASPI
CLPT
CLPT
Q4 25
0.07×
1.75×
Q3 25
0.19×
1.84×
Q2 25
1.46×
Q1 25
Q4 24
Q3 24
Q2 24
0.31×
Q1 24
0.29×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ASPI
ASPI
CLPT
CLPT
Operating Cash FlowLast quarter
$-37.8M
$-12.1M
Free Cash FlowOCF − Capex
$-47.4M
$-12.1M
FCF MarginFCF / Revenue
-284.7%
-116.5%
Capex IntensityCapex / Revenue
57.9%
0.5%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-24.4M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ASPI
ASPI
CLPT
CLPT
Q4 25
$-37.8M
$-12.1M
Q3 25
$-8.9M
$-3.1M
Q2 25
$-2.6M
Q1 25
$-6.2M
Q4 24
$-1.2M
Q3 24
$-1.2M
Q2 24
$-2.7M
Q1 24
$-3.8M
Free Cash Flow
ASPI
ASPI
CLPT
CLPT
Q4 25
$-47.4M
$-12.1M
Q3 25
$-12.0M
$-3.3M
Q2 25
$-2.6M
Q1 25
$-6.4M
Q4 24
$-1.5M
Q3 24
$-1.2M
Q2 24
Q1 24
FCF Margin
ASPI
ASPI
CLPT
CLPT
Q4 25
-284.7%
-116.5%
Q3 25
-245.5%
-37.5%
Q2 25
-28.7%
Q1 25
-74.9%
Q4 24
-19.4%
Q3 24
-14.9%
Q2 24
Q1 24
Capex Intensity
ASPI
ASPI
CLPT
CLPT
Q4 25
57.9%
0.5%
Q3 25
64.4%
2.2%
Q2 25
1.0%
Q1 25
2.2%
Q4 24
3.4%
Q3 24
0.1%
Q2 24
0.0%
Q1 24
0.0%

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

ASPI
ASPI

Segment breakdown not available.

CLPT
CLPT

Neurosurgery Navigation And Therapy Disposable Products$4.7M45%
Biologics And Drug Delivery Services And License Fees$2.8M27%
Biologics And Drug Delivery Disposable Products$2.4M23%
Other$502.0K5%

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