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Side-by-side financial comparison of ASP Isotopes Inc. (ASPI) and Intellia Therapeutics, Inc. (NTLA). Click either name above to swap in a different company.

Intellia Therapeutics, Inc. is the larger business by last-quarter revenue ($23.0M vs $16.7M, roughly 1.4× ASP Isotopes Inc.). On growth, ASP Isotopes Inc. posted the faster year-over-year revenue change (1295.7% vs 78.8%). ASP Isotopes Inc. produced more free cash flow last quarter ($-47.4M vs $-69.4M).

ASP Isotopes Inc. is a specialty materials firm focused on developing and producing high-purity custom isotopes. Its products serve key sectors including nuclear medicine, targeted cancer therapies, advanced energy, and industrial research, with customers across North America, Europe and Asia Pacific.

Intellia Therapeutics, Inc. is an American clinical-stage biotechnology company focused on developing novel, potentially curative therapeutics leveraging CRISPR-based technologies. The company's in vivo programs use intravenously administered CRISPR as the therapy, in which the company's proprietary delivery technology enables highly precise editing of disease-causing genes directly within specific target tissues. Intellia's ex vivo programs use CRISPR to create the therapy by using engineere...

ASPI vs NTLA — Head-to-Head

Bigger by revenue
NTLA
NTLA
1.4× larger
NTLA
$23.0M
$16.7M
ASPI
Growing faster (revenue YoY)
ASPI
ASPI
+1216.9% gap
ASPI
1295.7%
78.8%
NTLA
More free cash flow
ASPI
ASPI
$22.0M more FCF
ASPI
$-47.4M
$-69.4M
NTLA

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
ASPI
ASPI
NTLA
NTLA
Revenue
$16.7M
$23.0M
Net Profit
$-95.8M
Gross Margin
12.5%
Operating Margin
-428.9%
Net Margin
-416.2%
Revenue YoY
1295.7%
78.8%
Net Profit YoY
-586.8%
25.7%
EPS (diluted)
$-0.81

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ASPI
ASPI
NTLA
NTLA
Q4 25
$16.7M
$23.0M
Q3 25
$4.9M
$13.8M
Q2 25
$14.2M
Q1 25
$16.6M
Q4 24
$12.9M
Q3 24
$9.1M
Q2 24
$7.0M
Q1 24
$28.9M
Net Profit
ASPI
ASPI
NTLA
NTLA
Q4 25
$-95.8M
Q3 25
$-12.9M
$-101.3M
Q2 25
$-101.3M
Q1 25
$-114.3M
Q4 24
$-128.9M
Q3 24
$-135.7M
Q2 24
$-147.0M
Q1 24
$-107.4M
Gross Margin
ASPI
ASPI
NTLA
NTLA
Q4 25
12.5%
Q3 25
8.7%
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
Operating Margin
ASPI
ASPI
NTLA
NTLA
Q4 25
-428.9%
Q3 25
-306.1%
-808.9%
Q2 25
-772.2%
Q1 25
-726.6%
Q4 24
-1059.9%
Q3 24
-1589.0%
Q2 24
-1998.6%
Q1 24
-394.0%
Net Margin
ASPI
ASPI
NTLA
NTLA
Q4 25
-416.2%
Q3 25
-263.7%
-735.2%
Q2 25
-710.8%
Q1 25
-687.6%
Q4 24
-1001.2%
Q3 24
-1489.5%
Q2 24
-2112.6%
Q1 24
-371.3%
EPS (diluted)
ASPI
ASPI
NTLA
NTLA
Q4 25
$-0.81
Q3 25
$-0.15
$-0.92
Q2 25
$-0.98
Q1 25
$-1.10
Q4 24
$-1.27
Q3 24
$-1.34
Q2 24
$-1.52
Q1 24
$-1.12

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ASPI
ASPI
NTLA
NTLA
Cash + ST InvestmentsLiquidity on hand
$333.3M
$449.9M
Total DebtLower is stronger
$14.4M
Stockholders' EquityBook value
$204.2M
$671.4M
Total Assets
$498.0M
$842.1M
Debt / EquityLower = less leverage
0.07×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ASPI
ASPI
NTLA
NTLA
Q4 25
$333.3M
$449.9M
Q3 25
$113.9M
$511.0M
Q2 25
$459.7M
Q1 25
$503.7M
Q4 24
$601.5M
Q3 24
$658.1M
Q2 24
$691.1M
Q1 24
$791.3M
Total Debt
ASPI
ASPI
NTLA
NTLA
Q4 25
$14.4M
Q3 25
$13.9M
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
Stockholders' Equity
ASPI
ASPI
NTLA
NTLA
Q4 25
$204.2M
$671.4M
Q3 25
$74.1M
$748.4M
Q2 25
$715.3M
Q1 25
$779.9M
Q4 24
$872.0M
Q3 24
$962.6M
Q2 24
$971.1M
Q1 24
$1.0B
Total Assets
ASPI
ASPI
NTLA
NTLA
Q4 25
$498.0M
$842.1M
Q3 25
$225.9M
$925.3M
Q2 25
$898.9M
Q1 25
$986.2M
Q4 24
$1.2B
Q3 24
$1.2B
Q2 24
$1.2B
Q1 24
$1.3B
Debt / Equity
ASPI
ASPI
NTLA
NTLA
Q4 25
0.07×
Q3 25
0.19×
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ASPI
ASPI
NTLA
NTLA
Operating Cash FlowLast quarter
$-37.8M
$-69.3M
Free Cash FlowOCF − Capex
$-47.4M
$-69.4M
FCF MarginFCF / Revenue
-284.7%
-301.6%
Capex IntensityCapex / Revenue
57.9%
0.5%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-395.9M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ASPI
ASPI
NTLA
NTLA
Q4 25
$-37.8M
$-69.3M
Q3 25
$-8.9M
$-76.9M
Q2 25
$-99.6M
Q1 25
$-148.9M
Q4 24
$-85.2M
Q3 24
$-84.8M
Q2 24
$-58.2M
Q1 24
$-120.7M
Free Cash Flow
ASPI
ASPI
NTLA
NTLA
Q4 25
$-47.4M
$-69.4M
Q3 25
$-12.0M
$-76.9M
Q2 25
$-99.9M
Q1 25
$-149.7M
Q4 24
$-86.2M
Q3 24
$-86.1M
Q2 24
$-59.2M
Q1 24
$-123.2M
FCF Margin
ASPI
ASPI
NTLA
NTLA
Q4 25
-284.7%
-301.6%
Q3 25
-245.5%
-558.2%
Q2 25
-701.0%
Q1 25
-900.1%
Q4 24
-669.4%
Q3 24
-945.2%
Q2 24
-850.9%
Q1 24
-425.7%
Capex Intensity
ASPI
ASPI
NTLA
NTLA
Q4 25
57.9%
0.5%
Q3 25
64.4%
0.2%
Q2 25
1.7%
Q1 25
4.4%
Q4 24
7.6%
Q3 24
14.0%
Q2 24
14.5%
Q1 24
8.7%

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

ASPI
ASPI

Segment breakdown not available.

NTLA
NTLA

Avencell Therapeutics Inc$21.0M91%
Other$1.0M4%
Avencell$1.0M4%

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