vs

Side-by-side financial comparison of ASP Isotopes Inc. (ASPI) and RYTHM, Inc. (RYM). Click either name above to swap in a different company.

ASP Isotopes Inc. is the larger business by last-quarter revenue ($16.7M vs $10.7M, roughly 1.6× RYTHM, Inc.). On growth, ASP Isotopes Inc. posted the faster year-over-year revenue change (1295.7% vs 242.0%).

ASP Isotopes Inc. is a specialty materials firm focused on developing and producing high-purity custom isotopes. Its products serve key sectors including nuclear medicine, targeted cancer therapies, advanced energy, and industrial research, with customers across North America, Europe and Asia Pacific.

RYTHM, Inc. is a clinical-stage biopharmaceutical company focused on discovering, developing and commercializing innovative therapies for rare genetic endocrine and metabolic disorders with high unmet medical needs. It primarily operates in the U.S. market, targeting pediatric and adult patient segments that lack standard effective treatment options.

ASPI vs RYM — Head-to-Head

Bigger by revenue
ASPI
ASPI
1.6× larger
ASPI
$16.7M
$10.7M
RYM
Growing faster (revenue YoY)
ASPI
ASPI
+1053.7% gap
ASPI
1295.7%
242.0%
RYM

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
ASPI
ASPI
RYM
RYM
Revenue
$16.7M
$10.7M
Net Profit
$-13.6M
Gross Margin
12.5%
75.5%
Operating Margin
-121.5%
Net Margin
-127.6%
Revenue YoY
1295.7%
242.0%
Net Profit YoY
-586.8%
44.1%
EPS (diluted)
$-6.78

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ASPI
ASPI
RYM
RYM
Q4 25
$16.7M
$10.7M
Q3 25
$4.9M
$4.0M
Q2 25
$2.0M
Q1 25
$538.0K
Q4 24
$-7.5M
Q3 24
$1.9M
Q2 24
$3.0M
Q1 24
$2.6M
Net Profit
ASPI
ASPI
RYM
RYM
Q4 25
$-13.6M
Q3 25
$-12.9M
$-10.7M
Q2 25
$-7.4M
Q1 25
$-1.6M
Q4 24
$-24.4M
Q3 24
$-18.7M
Q2 24
$-3.0M
Q1 24
$4.2M
Gross Margin
ASPI
ASPI
RYM
RYM
Q4 25
12.5%
75.5%
Q3 25
8.7%
34.0%
Q2 25
33.4%
Q1 25
16.7%
Q4 24
Q3 24
11.6%
Q2 24
37.6%
Q1 24
6.4%
Operating Margin
ASPI
ASPI
RYM
RYM
Q4 25
-121.5%
Q3 25
-306.1%
-219.8%
Q2 25
-332.9%
Q1 25
-687.9%
Q4 24
Q3 24
-63.1%
Q2 24
-28.5%
Q1 24
13.6%
Net Margin
ASPI
ASPI
RYM
RYM
Q4 25
-127.6%
Q3 25
-263.7%
-263.8%
Q2 25
-360.4%
Q1 25
-302.2%
Q4 24
324.4%
Q3 24
-964.4%
Q2 24
-99.3%
Q1 24
163.0%
EPS (diluted)
ASPI
ASPI
RYM
RYM
Q4 25
$-6.78
Q3 25
$-0.15
$-5.33
Q2 25
$-3.74
Q1 25
$-0.83
Q4 24
$-24.26
Q3 24
$-17.28
Q2 24
$-3.16
Q1 24
$3.78

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ASPI
ASPI
RYM
RYM
Cash + ST InvestmentsLiquidity on hand
$333.3M
$32.2M
Total DebtLower is stronger
$14.4M
$80.6M
Stockholders' EquityBook value
$204.2M
$13.0M
Total Assets
$498.0M
$106.7M
Debt / EquityLower = less leverage
0.07×
6.19×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ASPI
ASPI
RYM
RYM
Q4 25
$333.3M
$32.2M
Q3 25
$113.9M
Q2 25
$41.0M
Q1 25
$24.4M
Q4 24
Q3 24
$267.0K
Q2 24
$57.0K
Q1 24
$99.0K
Total Debt
ASPI
ASPI
RYM
RYM
Q4 25
$14.4M
$80.6M
Q3 25
$13.9M
$90.6M
Q2 25
$40.6M
Q1 25
$10.6M
Q4 24
Q3 24
$6.2M
Q2 24
$4.6M
Q1 24
Stockholders' Equity
ASPI
ASPI
RYM
RYM
Q4 25
$204.2M
$13.0M
Q3 25
$74.1M
$11.7M
Q2 25
$21.0M
Q1 25
$26.8M
Q4 24
$28.1M
Q3 24
$5.5M
Q2 24
$8.5M
Q1 24
$-5.5M
Total Assets
ASPI
ASPI
RYM
RYM
Q4 25
$498.0M
$106.7M
Q3 25
$225.9M
$115.2M
Q2 25
$69.5M
Q1 25
$45.6M
Q4 24
$54.0M
Q3 24
$39.0M
Q2 24
$39.4M
Q1 24
$40.6M
Debt / Equity
ASPI
ASPI
RYM
RYM
Q4 25
0.07×
6.19×
Q3 25
0.19×
7.73×
Q2 25
1.94×
Q1 25
0.40×
Q4 24
Q3 24
1.13×
Q2 24
0.54×
Q1 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ASPI
ASPI
RYM
RYM
Operating Cash FlowLast quarter
$-37.8M
$-3.0M
Free Cash FlowOCF − Capex
$-47.4M
FCF MarginFCF / Revenue
-284.7%
Capex IntensityCapex / Revenue
57.9%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ASPI
ASPI
RYM
RYM
Q4 25
$-37.8M
$-3.0M
Q3 25
$-8.9M
$-5.4M
Q2 25
$-8.4M
Q1 25
$-6.7M
Q4 24
$-5.3M
Q3 24
$-1.4M
Q2 24
$-1.8M
Q1 24
$-3.0M
Free Cash Flow
ASPI
ASPI
RYM
RYM
Q4 25
$-47.4M
Q3 25
$-12.0M
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
$-1.8M
Q1 24
$-3.0M
FCF Margin
ASPI
ASPI
RYM
RYM
Q4 25
-284.7%
Q3 25
-245.5%
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
-61.2%
Q1 24
-115.1%
Capex Intensity
ASPI
ASPI
RYM
RYM
Q4 25
57.9%
Q3 25
64.4%
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
0.1%
Q1 24
0.1%
Cash Conversion
ASPI
ASPI
RYM
RYM
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
-0.71×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

ASPI
ASPI

Segment breakdown not available.

RYM
RYM

Nonlicensing Revenue$9.5M89%
Cultivation Business Discontinued Operations$1.2M11%

Related Comparisons