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Side-by-side financial comparison of ASP Isotopes Inc. (ASPI) and SUTRO BIOPHARMA, INC. (STRO). Click either name above to swap in a different company.

ASP Isotopes Inc. is the larger business by last-quarter revenue ($16.7M vs $11.6M, roughly 1.4× SUTRO BIOPHARMA, INC.). On growth, ASP Isotopes Inc. posted the faster year-over-year revenue change (1295.7% vs -21.4%).

ASP Isotopes Inc. is a specialty materials firm focused on developing and producing high-purity custom isotopes. Its products serve key sectors including nuclear medicine, targeted cancer therapies, advanced energy, and industrial research, with customers across North America, Europe and Asia Pacific.

Sutro Biopharma, Inc. is a publicly traded biotechnology company headquartered in South San Francisco, California focused on clinical-stage drug discovery, development and manufacturing. Using a proprietary cell-free protein synthesis platform, Sutro is working on oncology therapeutics using protein engineering and rational design. Founded in 2003 under the name Fundamental Applied Biology, the company name changed to Sutro Biopharma in 2009. William Newell, CEO as of 2024, joined Sutro in Ja...

ASPI vs STRO — Head-to-Head

Bigger by revenue
ASPI
ASPI
1.4× larger
ASPI
$16.7M
$11.6M
STRO
Growing faster (revenue YoY)
ASPI
ASPI
+1317.0% gap
ASPI
1295.7%
-21.4%
STRO

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
ASPI
ASPI
STRO
STRO
Revenue
$16.7M
$11.6M
Net Profit
Gross Margin
12.5%
Operating Margin
Net Margin
Revenue YoY
1295.7%
-21.4%
Net Profit YoY
-586.8%
35.4%
EPS (diluted)

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ASPI
ASPI
STRO
STRO
Q4 25
$16.7M
$11.6M
Q3 25
$4.9M
$9.7M
Q2 25
$63.7M
Q1 25
$17.4M
Q4 24
$14.8M
Q3 24
$8.5M
Q2 24
$25.7M
Q1 24
$13.0M
Net Profit
ASPI
ASPI
STRO
STRO
Q4 25
Q3 25
$-12.9M
$-56.9M
Q2 25
$-11.5M
Q1 25
$-76.0M
Q4 24
$-72.4M
Q3 24
$-48.8M
Q2 24
$-48.0M
Q1 24
$-58.2M
Gross Margin
ASPI
ASPI
STRO
STRO
Q4 25
12.5%
Q3 25
8.7%
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
Operating Margin
ASPI
ASPI
STRO
STRO
Q4 25
Q3 25
-306.1%
-499.9%
Q2 25
-5.2%
Q1 25
-393.8%
Q4 24
-440.7%
Q3 24
-797.2%
Q2 24
-189.4%
Q1 24
-435.0%
Net Margin
ASPI
ASPI
STRO
STRO
Q4 25
Q3 25
-263.7%
-586.6%
Q2 25
-18.0%
Q1 25
-436.6%
Q4 24
-489.2%
Q3 24
-572.6%
Q2 24
-186.8%
Q1 24
-447.5%
EPS (diluted)
ASPI
ASPI
STRO
STRO
Q4 25
Q3 25
$-0.15
$-0.67
Q2 25
$-0.14
Q1 25
$-0.91
Q4 24
$-27.63
Q3 24
$-0.59
Q2 24
$-0.59
Q1 24
$-0.59

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ASPI
ASPI
STRO
STRO
Cash + ST InvestmentsLiquidity on hand
$333.3M
$141.4M
Total DebtLower is stronger
$14.4M
Stockholders' EquityBook value
$204.2M
$-132.5M
Total Assets
$498.0M
$173.8M
Debt / EquityLower = less leverage
0.07×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ASPI
ASPI
STRO
STRO
Q4 25
$333.3M
$141.4M
Q3 25
$113.9M
$167.6M
Q2 25
$205.1M
Q1 25
$249.0M
Q4 24
$316.9M
Q3 24
$388.3M
Q2 24
$375.6M
Q1 24
$267.6M
Total Debt
ASPI
ASPI
STRO
STRO
Q4 25
$14.4M
Q3 25
$13.9M
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
Stockholders' Equity
ASPI
ASPI
STRO
STRO
Q4 25
$204.2M
$-132.5M
Q3 25
$74.1M
$-87.3M
Q2 25
$-32.1M
Q1 25
$-25.8M
Q4 24
$44.6M
Q3 24
$111.2M
Q2 24
$152.2M
Q1 24
$98.0M
Total Assets
ASPI
ASPI
STRO
STRO
Q4 25
$498.0M
$173.8M
Q3 25
$225.9M
$209.7M
Q2 25
$262.4M
Q1 25
$321.4M
Q4 24
$387.2M
Q3 24
$451.8M
Q2 24
$489.0M
Q1 24
$403.4M
Debt / Equity
ASPI
ASPI
STRO
STRO
Q4 25
0.07×
Q3 25
0.19×
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ASPI
ASPI
STRO
STRO
Operating Cash FlowLast quarter
$-37.8M
$-177.2M
Free Cash FlowOCF − Capex
$-47.4M
FCF MarginFCF / Revenue
-284.7%
Capex IntensityCapex / Revenue
57.9%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ASPI
ASPI
STRO
STRO
Q4 25
$-37.8M
$-177.2M
Q3 25
$-8.9M
$-38.2M
Q2 25
$-44.7M
Q1 25
$-67.9M
Q4 24
$-71.7M
Q3 24
$-64.5M
Q2 24
$9.5M
Q1 24
$-64.7M
Free Cash Flow
ASPI
ASPI
STRO
STRO
Q4 25
$-47.4M
Q3 25
$-12.0M
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
FCF Margin
ASPI
ASPI
STRO
STRO
Q4 25
-284.7%
Q3 25
-245.5%
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
Capex Intensity
ASPI
ASPI
STRO
STRO
Q4 25
57.9%
Q3 25
64.4%
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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