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Side-by-side financial comparison of Autolus Therapeutics plc (AUTL) and Spire Global, Inc. (SPIR). Click either name above to swap in a different company.
Autolus Therapeutics plc is the larger business by last-quarter revenue ($21.2M vs $15.8M, roughly 1.3× Spire Global, Inc.). Spire Global, Inc. runs the higher net margin — -176.6% vs -373.3%, a 196.7% gap on every dollar of revenue. Spire Global, Inc. produced more free cash flow last quarter ($-16.2M vs $-72.3M).
Autolus Therapeutics plc is a clinical-stage biopharmaceutical company specializing in the development of next-generation engineered chimeric antigen receptor T-cell (CAR-T) therapies for the treatment of hematological malignancies and solid tumors. It operates in the global oncology biotech market, advancing a pipeline of targeted immunotherapy candidates across multiple clinical development stages.
Spire Global, Inc. is a space-to-cloud data and analytics company that specializes in the tracking of global data sets powered by a large constellation of nanosatellites, such as the tracking of maritime, aviation and weather patterns.
AUTL vs SPIR — Head-to-Head
Income Statement — Q3 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $21.2M | $15.8M |
| Net Profit | $-79.1M | $-28.0M |
| Gross Margin | — | 40.2% |
| Operating Margin | -337.9% | -164.1% |
| Net Margin | -373.3% | -176.6% |
| Revenue YoY | — | -26.9% |
| Net Profit YoY | 3.6% | 42.7% |
| EPS (diluted) | $-0.30 | $-0.85 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | — | $15.8M | ||
| Q3 25 | $21.2M | $12.7M | ||
| Q2 25 | $20.9M | $19.2M | ||
| Q1 25 | $9.0M | $23.9M | ||
| Q4 24 | — | $21.7M | ||
| Q3 24 | $0 | $28.6M | ||
| Q2 24 | $0 | $25.4M | ||
| Q1 24 | $10.1M | $34.8M |
| Q4 25 | — | $-28.0M | ||
| Q3 25 | $-79.1M | $-19.7M | ||
| Q2 25 | $-47.9M | $119.6M | ||
| Q1 25 | $-70.2M | $-20.7M | ||
| Q4 24 | — | $-48.8M | ||
| Q3 24 | $-82.1M | $-12.5M | ||
| Q2 24 | $-58.3M | $-16.6M | ||
| Q1 24 | $-52.7M | $-25.5M |
| Q4 25 | — | 40.2% | ||
| Q3 25 | — | 36.6% | ||
| Q2 25 | — | 48.9% | ||
| Q1 25 | — | 36.8% | ||
| Q4 24 | — | 32.4% | ||
| Q3 24 | — | 44.5% | ||
| Q2 24 | — | 43.0% | ||
| Q1 24 | — | 26.5% |
| Q4 25 | — | -164.1% | ||
| Q3 25 | -337.9% | -166.1% | ||
| Q2 25 | -292.6% | -122.7% | ||
| Q1 25 | -726.3% | -106.5% | ||
| Q4 24 | — | -144.1% | ||
| Q3 24 | — | -48.0% | ||
| Q2 24 | — | -48.6% | ||
| Q1 24 | -384.1% | -34.4% |
| Q4 25 | — | -176.6% | ||
| Q3 25 | -373.3% | -155.3% | ||
| Q2 25 | -229.0% | 623.4% | ||
| Q1 25 | -781.1% | -86.5% | ||
| Q4 24 | — | -225.2% | ||
| Q3 24 | — | -43.7% | ||
| Q2 24 | — | -65.2% | ||
| Q1 24 | -522.1% | -73.3% |
| Q4 25 | — | $-0.85 | ||
| Q3 25 | $-0.30 | $-0.61 | ||
| Q2 25 | $-0.18 | $3.72 | ||
| Q1 25 | $-0.26 | $-0.77 | ||
| Q4 24 | — | $-1.93 | ||
| Q3 24 | $-0.31 | $-0.50 | ||
| Q2 24 | $-0.22 | $-0.68 | ||
| Q1 24 | $-0.24 | $-1.17 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $86.1M | $81.8M |
| Total DebtLower is stronger | — | — |
| Stockholders' EquityBook value | $265.5M | $112.9M |
| Total Assets | $661.9M | $211.0M |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | — | $81.8M | ||
| Q3 25 | $86.1M | $96.8M | ||
| Q2 25 | $123.8M | $117.6M | ||
| Q1 25 | $95.8M | $35.9M | ||
| Q4 24 | — | $19.2M | ||
| Q3 24 | $657.1M | $36.6M | ||
| Q2 24 | $705.9M | $45.8M | ||
| Q1 24 | $758.5M | $63.7M |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | $103.7M | ||
| Q4 24 | — | $103.1M | ||
| Q3 24 | — | $4.9M | ||
| Q2 24 | — | $4.9M | ||
| Q1 24 | — | $123.1M |
| Q4 25 | — | $112.9M | ||
| Q3 25 | $265.5M | $133.1M | ||
| Q2 25 | $346.5M | $149.2M | ||
| Q1 25 | $371.1M | $3.7M | ||
| Q4 24 | — | $-11.7M | ||
| Q3 24 | $477.0M | $30.8M | ||
| Q2 24 | $527.8M | $40.3M | ||
| Q1 24 | $582.0M | $52.5M |
| Q4 25 | — | $211.0M | ||
| Q3 25 | $661.9M | $224.3M | ||
| Q2 25 | $721.0M | $239.5M | ||
| Q1 25 | $746.3M | $208.8M | ||
| Q4 24 | — | $193.6M | ||
| Q3 24 | $827.5M | $224.2M | ||
| Q2 24 | $853.6M | $230.8M | ||
| Q1 24 | $901.4M | $252.3M |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | 27.92× | ||
| Q4 24 | — | — | ||
| Q3 24 | — | 0.16× | ||
| Q2 24 | — | 0.12× | ||
| Q1 24 | — | 2.35× |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-67.9M | $-4.3M |
| Free Cash FlowOCF − Capex | $-72.3M | $-16.2M |
| FCF MarginFCF / Revenue | -341.2% | -102.1% |
| Capex IntensityCapex / Revenue | 20.8% | 75.1% |
| Cash ConversionOCF / Net Profit | — | — |
| TTM Free Cash FlowTrailing 4 quarters | $-322.5M | $-92.6M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | — | $-4.3M | ||
| Q3 25 | $-67.9M | $-12.0M | ||
| Q2 25 | $-72.8M | $-35.1M | ||
| Q1 25 | $-75.6M | $-8.4M | ||
| Q4 24 | — | $-19.2M | ||
| Q3 24 | $-76.7M | $14.0M | ||
| Q2 24 | $-51.1M | $-4.4M | ||
| Q1 24 | $-40.5M | $-8.8M |
| Q4 25 | — | $-16.2M | ||
| Q3 25 | $-72.3M | $-20.4M | ||
| Q2 25 | $-80.1M | $-38.7M | ||
| Q1 25 | $-83.8M | $-17.3M | ||
| Q4 24 | — | $-24.3M | ||
| Q3 24 | $-86.3M | $5.1M | ||
| Q2 24 | $-51.9M | $-9.9M | ||
| Q1 24 | $-41.0M | $-15.9M |
| Q4 25 | — | -102.1% | ||
| Q3 25 | -341.2% | -161.3% | ||
| Q2 25 | -382.6% | -201.7% | ||
| Q1 25 | -933.1% | -72.6% | ||
| Q4 24 | — | -112.2% | ||
| Q3 24 | — | 17.8% | ||
| Q2 24 | — | -39.0% | ||
| Q1 24 | -406.8% | -45.7% |
| Q4 25 | — | 75.1% | ||
| Q3 25 | 20.8% | 66.2% | ||
| Q2 25 | 34.8% | 18.8% | ||
| Q1 25 | 91.8% | 37.3% | ||
| Q4 24 | — | 23.5% | ||
| Q3 24 | — | 31.2% | ||
| Q2 24 | — | 21.8% | ||
| Q1 24 | 5.3% | 20.3% |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | -0.29× | ||
| Q1 25 | — | — | ||
| Q4 24 | — | — | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
