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Side-by-side financial comparison of American Express (AXP) and Pfizer (PFE). Click either name above to swap in a different company.

Pfizer is the larger business by last-quarter revenue ($17.6B vs $10.9B, roughly 1.6× American Express). American Express runs the higher net margin — 22.5% vs -9.4%, a 31.9% gap on every dollar of revenue. On growth, American Express posted the faster year-over-year revenue change (9.9% vs -1.2%). Pfizer produced more free cash flow last quarter ($4.5B vs $2.3B). Over the past eight quarters, Pfizer's revenue compounded faster (8.6% CAGR vs 8.2%).

American Express Company, together with its subsidiaries, provides charge and credit payment card products, and travel-related services worldwide. The company operates through three segments: Global Consumer Services Group, Global Commercial Services, and Global Merchant and Network Services. Its products and services include payment and financing products; network services; accounts payable expense management products and services; and travel and lifestyle services. The company's products an...

Pfizer Inc. is an American multinational pharmaceutical and biotechnology corporation headquartered at The Spiral in Manhattan, New York City. Founded in 1849 in New York by German entrepreneurs Charles Pfizer (1824–1906) and Charles F. Erhart (1821–1891), Pfizer is one of the oldest pharmaceutical companies in North America.

AXP vs PFE — Head-to-Head

Bigger by revenue
PFE
PFE
1.6× larger
PFE
$17.6B
$10.9B
AXP
Growing faster (revenue YoY)
AXP
AXP
+11.1% gap
AXP
9.9%
-1.2%
PFE
Higher net margin
AXP
AXP
31.9% more per $
AXP
22.5%
-9.4%
PFE
More free cash flow
PFE
PFE
$2.2B more FCF
PFE
$4.5B
$2.3B
AXP
Faster 2-yr revenue CAGR
PFE
PFE
Annualised
PFE
8.6%
8.2%
AXP

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
AXP
AXP
PFE
PFE
Revenue
$10.9B
$17.6B
Net Profit
$2.5B
$-1.6B
Gross Margin
70.0%
Operating Margin
28.2%
-9.4%
Net Margin
22.5%
-9.4%
Revenue YoY
9.9%
-1.2%
Net Profit YoY
13.5%
-501.7%
EPS (diluted)
$3.52
$-0.29

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
AXP
AXP
PFE
PFE
Q4 25
$10.9B
$17.6B
Q3 25
$10.4B
$16.7B
Q2 25
$10.3B
$14.7B
Q1 25
$9.6B
$13.7B
Q4 24
$10.0B
$17.8B
Q3 24
$9.7B
$17.7B
Q2 24
$9.8B
$13.3B
Q1 24
$9.3B
$14.9B
Net Profit
AXP
AXP
PFE
PFE
Q4 25
$2.5B
$-1.6B
Q3 25
$2.9B
$3.5B
Q2 25
$2.9B
$2.9B
Q1 25
$2.6B
$3.0B
Q4 24
$2.2B
$410.0M
Q3 24
$2.5B
$4.5B
Q2 24
$3.0B
$41.0M
Q1 24
$2.4B
$3.1B
Gross Margin
AXP
AXP
PFE
PFE
Q4 25
70.0%
Q3 25
74.9%
Q2 25
74.2%
Q1 25
79.3%
Q4 24
66.7%
Q3 24
70.3%
Q2 24
75.2%
Q1 24
77.3%
Operating Margin
AXP
AXP
PFE
PFE
Q4 25
28.2%
-9.4%
Q3 25
36.7%
20.0%
Q2 25
34.4%
20.8%
Q1 25
34.6%
20.3%
Q4 24
27.7%
-0.1%
Q3 24
33.0%
26.6%
Q2 24
38.6%
-0.8%
Q1 24
33.7%
23.0%
Net Margin
AXP
AXP
PFE
PFE
Q4 25
22.5%
-9.4%
Q3 25
27.9%
21.3%
Q2 25
28.0%
19.9%
Q1 25
26.8%
21.6%
Q4 24
21.8%
2.3%
Q3 24
25.8%
25.2%
Q2 24
30.7%
0.3%
Q1 24
26.1%
20.9%
EPS (diluted)
AXP
AXP
PFE
PFE
Q4 25
$3.52
$-0.29
Q3 25
$4.14
$0.62
Q2 25
$4.08
$0.51
Q1 25
$3.64
$0.52
Q4 24
$3.04
$0.07
Q3 24
$3.49
$0.78
Q2 24
$4.15
$0.01
Q1 24
$3.33
$0.55

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
AXP
AXP
PFE
PFE
Cash + ST InvestmentsLiquidity on hand
$742.0M
$1.1B
Total DebtLower is stronger
$56.4B
Stockholders' EquityBook value
$33.5B
$86.5B
Total Assets
$300.1B
$208.2B
Debt / EquityLower = less leverage
1.68×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
AXP
AXP
PFE
PFE
Q4 25
$742.0M
$1.1B
Q3 25
$1.3B
$1.3B
Q2 25
$197.0M
$1.6B
Q1 25
$261.0M
$1.4B
Q4 24
$221.0M
$1.0B
Q3 24
$120.0M
$1.1B
Q2 24
$188.0M
$1.1B
Q1 24
$69.0M
$719.0M
Total Debt
AXP
AXP
PFE
PFE
Q4 25
$56.4B
Q3 25
$57.8B
Q2 25
$58.2B
Q1 25
$51.2B
Q4 24
$49.7B
Q3 24
$53.5B
Q2 24
$51.5B
Q1 24
$48.8B
Stockholders' Equity
AXP
AXP
PFE
PFE
Q4 25
$33.5B
$86.5B
Q3 25
$32.4B
$92.8B
Q2 25
$32.3B
$88.7B
Q1 25
$31.2B
$90.3B
Q4 24
$30.3B
$88.2B
Q3 24
$29.7B
$92.3B
Q2 24
$29.5B
$87.7B
Q1 24
$28.8B
$92.3B
Total Assets
AXP
AXP
PFE
PFE
Q4 25
$300.1B
$208.2B
Q3 25
$297.6B
$208.7B
Q2 25
$295.6B
$206.1B
Q1 25
$282.2B
$208.0B
Q4 24
$271.5B
$213.4B
Q3 24
$271.0B
$219.5B
Q2 24
$272.2B
$216.2B
Q1 24
$269.3B
$221.1B
Debt / Equity
AXP
AXP
PFE
PFE
Q4 25
1.68×
Q3 25
1.78×
Q2 25
1.80×
Q1 25
1.64×
Q4 24
1.64×
Q3 24
1.80×
Q2 24
1.74×
Q1 24
1.70×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
AXP
AXP
PFE
PFE
Operating Cash FlowLast quarter
$3.1B
$5.3B
Free Cash FlowOCF − Capex
$2.3B
$4.5B
FCF MarginFCF / Revenue
21.4%
25.6%
Capex IntensityCapex / Revenue
6.6%
4.8%
Cash ConversionOCF / Net Profit
1.25×
TTM Free Cash FlowTrailing 4 quarters
$16.0B
$9.1B

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
AXP
AXP
PFE
PFE
Q4 25
$3.1B
$5.3B
Q3 25
$6.2B
$4.6B
Q2 25
$4.4B
$-582.0M
Q1 25
$4.8B
$2.3B
Q4 24
$5.8B
$6.7B
Q3 24
$-1.8B
$6.7B
Q2 24
$4.5B
$-1.8B
Q1 24
$5.6B
$1.1B
Free Cash Flow
AXP
AXP
PFE
PFE
Q4 25
$2.3B
$4.5B
Q3 25
$5.6B
$4.0B
Q2 25
$3.7B
$-1.2B
Q1 25
$4.3B
$1.8B
Q4 24
$5.3B
$5.8B
Q3 24
$-2.3B
$6.1B
Q2 24
$4.0B
$-2.4B
Q1 24
$5.2B
$386.0M
FCF Margin
AXP
AXP
PFE
PFE
Q4 25
21.4%
25.6%
Q3 25
53.6%
24.0%
Q2 25
36.3%
-8.2%
Q1 25
45.0%
12.9%
Q4 24
53.1%
32.7%
Q3 24
-23.3%
34.3%
Q2 24
40.4%
-18.2%
Q1 24
55.2%
2.6%
Capex Intensity
AXP
AXP
PFE
PFE
Q4 25
6.6%
4.8%
Q3 25
6.3%
3.6%
Q2 25
6.0%
4.2%
Q1 25
4.5%
4.1%
Q4 24
5.0%
5.2%
Q3 24
4.7%
3.7%
Q2 24
5.8%
4.8%
Q1 24
4.2%
4.7%
Cash Conversion
AXP
AXP
PFE
PFE
Q4 25
1.25×
Q3 25
2.15×
1.30×
Q2 25
1.51×
-0.20×
Q1 25
1.84×
0.79×
Q4 24
2.66×
16.39×
Q3 24
-0.72×
1.50×
Q2 24
1.50×
-43.44×
Q1 24
2.28×
0.35×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

AXP
AXP

US Consumer Services Segment$4.2B38%
Commercial Services Segment$3.1B28%
International Card Services Segment$2.1B19%
Global Merchant And Network Services Segment$1.7B15%
Financial Service Other$471.0M4%

PFE
PFE

U.S.Commercial Division$9.0B51%
Specialty Care$4.8B27%
Total Alliance Biopharmaceuticals$2.6B15%
Royalty$480.0M3%
Pfizer Centre One$409.0M2%

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