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Side-by-side financial comparison of Axsome Therapeutics, Inc. (AXSM) and IDEAYA Biosciences, Inc. (IDYA). Click either name above to swap in a different company.

IDEAYA Biosciences, Inc. is the larger business by last-quarter revenue ($207.8M vs $196.0M, roughly 1.1× Axsome Therapeutics, Inc.). IDEAYA Biosciences, Inc. runs the higher net margin — 57.4% vs -14.6%, a 71.9% gap on every dollar of revenue. IDEAYA Biosciences, Inc. produced more free cash flow last quarter ($142.2M vs $-18.7M).

Jazz Pharmaceuticals plc is a global biopharmaceutical company with a focus on oncology and neuroscience. It was founded in 2003 in California, United States and is now headquartered in Dublin, Ireland.

IDEAYA Biosciences, Inc. is a clinical-stage biotechnology company focused on oncology, developing targeted therapies and synthetic lethality treatments for patients with genetically defined cancers. It advances a pipeline of candidates across multiple tumor types, partnering with industry stakeholders to accelerate global access to innovative cancer care solutions.

AXSM vs IDYA — Head-to-Head

Bigger by revenue
IDYA
IDYA
1.1× larger
IDYA
$207.8M
$196.0M
AXSM
Higher net margin
IDYA
IDYA
71.9% more per $
IDYA
57.4%
-14.6%
AXSM
More free cash flow
IDYA
IDYA
$160.9M more FCF
IDYA
$142.2M
$-18.7M
AXSM

Income Statement — Q4 FY2025 vs Q3 FY2025

Metric
AXSM
AXSM
IDYA
IDYA
Revenue
$196.0M
$207.8M
Net Profit
$-28.6M
$119.2M
Gross Margin
Operating Margin
-13.8%
52.2%
Net Margin
-14.6%
57.4%
Revenue YoY
65.0%
Net Profit YoY
61.9%
330.1%
EPS (diluted)
$-0.55
$1.33

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
AXSM
AXSM
IDYA
IDYA
Q4 25
$196.0M
Q3 25
$171.0M
$207.8M
Q2 25
$150.0M
Q1 25
$121.5M
Q4 24
$118.8M
Q3 24
$104.8M
$0
Q2 24
$87.2M
$0
Q1 24
$75.0M
$0
Net Profit
AXSM
AXSM
IDYA
IDYA
Q4 25
$-28.6M
Q3 25
$-47.2M
$119.2M
Q2 25
$-48.0M
Q1 25
$-59.4M
Q4 24
$-74.9M
Q3 24
$-64.6M
$-51.8M
Q2 24
$-79.3M
$-52.8M
Q1 24
$-68.4M
$-39.6M
Operating Margin
AXSM
AXSM
IDYA
IDYA
Q4 25
-13.8%
Q3 25
-27.0%
52.2%
Q2 25
-24.5%
Q1 25
-46.9%
Q4 24
-61.1%
Q3 24
-59.8%
Q2 24
-89.5%
Q1 24
-89.7%
Net Margin
AXSM
AXSM
IDYA
IDYA
Q4 25
-14.6%
Q3 25
-27.6%
57.4%
Q2 25
-32.0%
Q1 25
-48.9%
Q4 24
-63.1%
Q3 24
-61.7%
Q2 24
-91.0%
Q1 24
-91.1%
EPS (diluted)
AXSM
AXSM
IDYA
IDYA
Q4 25
$-0.55
Q3 25
$-0.94
$1.33
Q2 25
$-0.97
Q1 25
$-1.22
Q4 24
$-1.54
Q3 24
$-1.34
$-0.60
Q2 24
$-1.67
$-0.68
Q1 24
$-1.44
$-0.53

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
AXSM
AXSM
IDYA
IDYA
Cash + ST InvestmentsLiquidity on hand
$322.9M
$786.9M
Total DebtLower is stronger
Stockholders' EquityBook value
$88.3M
$1.1B
Total Assets
$689.8M
$1.2B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
AXSM
AXSM
IDYA
IDYA
Q4 25
$322.9M
Q3 25
$325.3M
$786.9M
Q2 25
$303.0M
Q1 25
$300.9M
Q4 24
$315.4M
Q3 24
$327.3M
$920.0M
Q2 24
$315.7M
$701.7M
Q1 24
$331.4M
$698.8M
Stockholders' Equity
AXSM
AXSM
IDYA
IDYA
Q4 25
$88.3M
Q3 25
$73.7M
$1.1B
Q2 25
$73.1M
Q1 25
$53.2M
Q4 24
$57.0M
Q3 24
$92.9M
$1.2B
Q2 24
$102.9M
$931.7M
Q1 24
$144.0M
$935.3M
Total Assets
AXSM
AXSM
IDYA
IDYA
Q4 25
$689.8M
Q3 25
$669.3M
$1.2B
Q2 25
$639.8M
Q1 25
$596.7M
Q4 24
$568.5M
Q3 24
$561.5M
$1.2B
Q2 24
$548.2M
$973.7M
Q1 24
$545.7M
$961.5M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
AXSM
AXSM
IDYA
IDYA
Operating Cash FlowLast quarter
$-18.7M
$142.2M
Free Cash FlowOCF − Capex
$-18.7M
$142.2M
FCF MarginFCF / Revenue
-9.6%
68.4%
Capex IntensityCapex / Revenue
0.0%
0.0%
Cash ConversionOCF / Net Profit
1.19×
TTM Free Cash FlowTrailing 4 quarters
$-93.9M
$13.5M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
AXSM
AXSM
IDYA
IDYA
Q4 25
$-18.7M
Q3 25
$1.0M
$142.2M
Q2 25
$-32.4M
Q1 25
$-43.4M
Q4 24
$-26.2M
Q3 24
$-18.6M
$-49.2M
Q2 24
$-30.1M
$-32.9M
Q1 24
$-53.5M
$-43.8M
Free Cash Flow
AXSM
AXSM
IDYA
IDYA
Q4 25
$-18.7M
Q3 25
$988.0K
$142.2M
Q2 25
$-32.4M
Q1 25
$-43.7M
Q4 24
$-26.2M
Q3 24
$-18.7M
$-49.7M
Q2 24
$-30.2M
$-33.9M
Q1 24
$-53.6M
$-45.1M
FCF Margin
AXSM
AXSM
IDYA
IDYA
Q4 25
-9.6%
Q3 25
0.6%
68.4%
Q2 25
-21.6%
Q1 25
-36.0%
Q4 24
-22.1%
Q3 24
-17.9%
Q2 24
-34.6%
Q1 24
-71.4%
Capex Intensity
AXSM
AXSM
IDYA
IDYA
Q4 25
0.0%
Q3 25
0.0%
0.0%
Q2 25
0.0%
Q1 25
0.3%
Q4 24
0.0%
Q3 24
0.1%
Q2 24
0.1%
Q1 24
0.1%
Cash Conversion
AXSM
AXSM
IDYA
IDYA
Q4 25
Q3 25
1.19×
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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