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Side-by-side financial comparison of Axsome Therapeutics, Inc. (AXSM) and Safehold Inc. (SAFE). Click either name above to swap in a different company.
Axsome Therapeutics, Inc. is the larger business by last-quarter revenue ($191.2M vs $97.9M, roughly 2.0× Safehold Inc.). On growth, Axsome Therapeutics, Inc. posted the faster year-over-year revenue change (57.4% vs 6.5%). Over the past eight quarters, Axsome Therapeutics, Inc.'s revenue compounded faster (48.1% CAGR vs 2.5%).
Jazz Pharmaceuticals plc is a global biopharmaceutical company with a focus on oncology and neuroscience. It was founded in 2003 in California, United States and is now headquartered in Dublin, Ireland.
SAFE Investment Company Limited is a Chinese sovereign wealth fund based in Hong Kong.
AXSM vs SAFE — Head-to-Head
Income Statement — Q1 FY2026 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $191.2M | $97.9M |
| Net Profit | — | $27.9M |
| Gross Margin | — | 98.6% |
| Operating Margin | -33.1% | 27.4% |
| Net Margin | — | 28.5% |
| Revenue YoY | 57.4% | 6.5% |
| Net Profit YoY | — | 7.1% |
| EPS (diluted) | — | $0.38 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q1 26 | $191.2M | — | ||
| Q4 25 | $196.0M | $97.9M | ||
| Q3 25 | $171.0M | $96.2M | ||
| Q2 25 | $150.0M | $93.8M | ||
| Q1 25 | $121.5M | $97.7M | ||
| Q4 24 | $118.8M | $91.9M | ||
| Q3 24 | $104.8M | $90.7M | ||
| Q2 24 | $87.2M | $89.9M |
| Q1 26 | — | — | ||
| Q4 25 | $-28.6M | $27.9M | ||
| Q3 25 | $-47.2M | $29.3M | ||
| Q2 25 | $-48.0M | $27.9M | ||
| Q1 25 | $-59.4M | $29.4M | ||
| Q4 24 | $-74.9M | $26.0M | ||
| Q3 24 | $-64.6M | $19.3M | ||
| Q2 24 | $-79.3M | $29.7M |
| Q1 26 | — | — | ||
| Q4 25 | — | 98.6% | ||
| Q3 25 | — | 98.5% | ||
| Q2 25 | — | 99.1% | ||
| Q1 25 | — | 98.8% | ||
| Q4 24 | — | 98.8% | ||
| Q3 24 | — | 98.8% | ||
| Q2 24 | — | 98.8% |
| Q1 26 | -33.1% | — | ||
| Q4 25 | -13.8% | 27.4% | ||
| Q3 25 | -27.0% | 25.9% | ||
| Q2 25 | -24.5% | 25.5% | ||
| Q1 25 | -46.9% | 25.9% | ||
| Q4 24 | -61.1% | 24.6% | ||
| Q3 24 | -59.8% | 17.5% | ||
| Q2 24 | -89.5% | 26.7% |
| Q1 26 | — | — | ||
| Q4 25 | -14.6% | 28.5% | ||
| Q3 25 | -27.6% | 30.5% | ||
| Q2 25 | -32.0% | 29.8% | ||
| Q1 25 | -48.9% | 30.1% | ||
| Q4 24 | -63.1% | 28.3% | ||
| Q3 24 | -61.7% | 21.3% | ||
| Q2 24 | -91.0% | 33.0% |
| Q1 26 | — | — | ||
| Q4 25 | $-0.55 | $0.38 | ||
| Q3 25 | $-0.94 | $0.41 | ||
| Q2 25 | $-0.97 | $0.39 | ||
| Q1 25 | $-1.22 | $0.41 | ||
| Q4 24 | $-1.54 | $0.36 | ||
| Q3 24 | $-1.34 | $0.27 | ||
| Q2 24 | $-1.67 | $0.42 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $305.1M | $21.7M |
| Total DebtLower is stronger | $70.0M | $4.6B |
| Stockholders' EquityBook value | — | $2.4B |
| Total Assets | $713.6M | $7.2B |
| Debt / EquityLower = less leverage | — | 1.90× |
8-quarter trend — quarters aligned by calendar period.
| Q1 26 | $305.1M | — | ||
| Q4 25 | $322.9M | $21.7M | ||
| Q3 25 | $325.3M | $12.1M | ||
| Q2 25 | $303.0M | $13.9M | ||
| Q1 25 | $300.9M | $17.3M | ||
| Q4 24 | $315.4M | $8.3M | ||
| Q3 24 | $327.3M | $15.6M | ||
| Q2 24 | $315.7M | $13.4M |
| Q1 26 | $70.0M | — | ||
| Q4 25 | — | $4.6B | ||
| Q3 25 | — | $4.5B | ||
| Q2 25 | — | $4.4B | ||
| Q1 25 | — | $4.3B | ||
| Q4 24 | — | $4.3B | ||
| Q3 24 | — | $4.3B | ||
| Q2 24 | — | $4.2B |
| Q1 26 | — | — | ||
| Q4 25 | $88.3M | $2.4B | ||
| Q3 25 | $73.7M | $2.4B | ||
| Q2 25 | $73.1M | $2.4B | ||
| Q1 25 | $53.2M | $2.4B | ||
| Q4 24 | $57.0M | $2.3B | ||
| Q3 24 | $92.9M | $2.3B | ||
| Q2 24 | $102.9M | $2.3B |
| Q1 26 | $713.6M | — | ||
| Q4 25 | $689.8M | $7.2B | ||
| Q3 25 | $669.3M | $7.1B | ||
| Q2 25 | $639.8M | $7.1B | ||
| Q1 25 | $596.7M | $6.9B | ||
| Q4 24 | $568.5M | $6.9B | ||
| Q3 24 | $561.5M | $6.8B | ||
| Q2 24 | $548.2M | $6.8B |
| Q1 26 | — | — | ||
| Q4 25 | — | 1.90× | ||
| Q3 25 | — | 1.89× | ||
| Q2 25 | — | 1.87× | ||
| Q1 25 | — | 1.85× | ||
| Q4 24 | — | 1.84× | ||
| Q3 24 | — | 1.88× | ||
| Q2 24 | — | 1.81× |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | — | $47.8M |
| Free Cash FlowOCF − Capex | — | — |
| FCF MarginFCF / Revenue | — | — |
| Capex IntensityCapex / Revenue | — | — |
| Cash ConversionOCF / Net Profit | — | 1.72× |
| TTM Free Cash FlowTrailing 4 quarters | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q1 26 | — | — | ||
| Q4 25 | $-18.7M | $47.8M | ||
| Q3 25 | $1.0M | $-1.4M | ||
| Q2 25 | $-32.4M | $28.0M | ||
| Q1 25 | $-43.4M | $8.9M | ||
| Q4 24 | $-26.2M | $37.9M | ||
| Q3 24 | $-18.6M | $8.3M | ||
| Q2 24 | $-30.1M | $24.8M |
| Q1 26 | — | — | ||
| Q4 25 | $-18.7M | — | ||
| Q3 25 | $988.0K | — | ||
| Q2 25 | $-32.4M | — | ||
| Q1 25 | $-43.7M | — | ||
| Q4 24 | $-26.2M | — | ||
| Q3 24 | $-18.7M | — | ||
| Q2 24 | $-30.2M | — |
| Q1 26 | — | — | ||
| Q4 25 | -9.6% | — | ||
| Q3 25 | 0.6% | — | ||
| Q2 25 | -21.6% | — | ||
| Q1 25 | -36.0% | — | ||
| Q4 24 | -22.1% | — | ||
| Q3 24 | -17.9% | — | ||
| Q2 24 | -34.6% | — |
| Q1 26 | — | — | ||
| Q4 25 | 0.0% | — | ||
| Q3 25 | 0.0% | — | ||
| Q2 25 | 0.0% | — | ||
| Q1 25 | 0.3% | — | ||
| Q4 24 | 0.0% | — | ||
| Q3 24 | 0.1% | — | ||
| Q2 24 | 0.1% | — |
| Q1 26 | — | — | ||
| Q4 25 | — | 1.72× | ||
| Q3 25 | — | -0.05× | ||
| Q2 25 | — | 1.00× | ||
| Q1 25 | — | 0.30× | ||
| Q4 24 | — | 1.45× | ||
| Q3 24 | — | 0.43× | ||
| Q2 24 | — | 0.83× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
AXSM
| Product sales, net | $189.4M | 99% |
| Royalty revenue and milestone revenue | $1.8M | 1% |
SAFE
| Equity Method Investment Nonconsolidated Investee Or Group Of Investees | $60.3M | 62% |
| Other | $33.7M | 34% |
| Stabilized Properties | $3.8M | 4% |
