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Side-by-side financial comparison of Bone Biologics Corp (BBLG) and SPRUCE BIOSCIENCES, INC. (SPRB). Click either name above to swap in a different company.

Bone Biologics Corp is a clinical-stage biotechnology firm focused on developing orthobiologic products to boost bone regeneration and healing for orthopedic surgery patients, including spinal fusion recipients. It mainly operates in the U.S. healthcare market, targeting orthopedic care and regenerative medicine segments.

Spruce Biosciences, Inc. is a late-stage biopharmaceutical firm focused on developing targeted therapies for rare endocrine and metabolic disorders with high unmet medical need. Its core pipeline includes candidates for congenital adrenal hyperplasia and Cushing’s syndrome, serving patients across North America, Europe and other developed markets.

BBLG vs SPRB — Head-to-Head

Bigger by revenue
BBLG
BBLG
Infinity× larger
BBLG
$255
$0
SPRB

Income Statement — Q1 FY2024 vs Q4 FY2025

Metric
BBLG
BBLG
SPRB
SPRB
Revenue
$255
$0
Net Profit
$-866.0K
$-14.6M
Gross Margin
Operating Margin
-354327.8%
Net Margin
-339596.1%
Revenue YoY
-54.1%
Net Profit YoY
76.7%
37.8%
EPS (diluted)
$-1.31
$-32.43

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
BBLG
BBLG
SPRB
SPRB
Q4 25
$0
Q3 25
$0
Q2 25
$0
Q1 25
$0
Q4 24
$697.0K
Q3 24
$602.0K
Q2 24
$1.6M
Q1 24
$255
$2.0M
Net Profit
BBLG
BBLG
SPRB
SPRB
Q4 25
$-14.6M
Q3 25
$-8.2M
Q2 25
$-2.1M
Q1 25
$-14.0M
Q4 24
$-23.6M
Q3 24
$-8.7M
Q2 24
$-9.2M
Q1 24
$-866.0K
$-11.6M
Operating Margin
BBLG
BBLG
SPRB
SPRB
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
-3453.9%
Q3 24
-1562.8%
Q2 24
-623.4%
Q1 24
-354327.8%
-631.0%
Net Margin
BBLG
BBLG
SPRB
SPRB
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
-3380.1%
Q3 24
-1440.4%
Q2 24
-570.2%
Q1 24
-339596.1%
-580.7%
EPS (diluted)
BBLG
BBLG
SPRB
SPRB
Q4 25
$-32.43
Q3 25
$-14.58
Q2 25
$-3.50
Q1 25
$-0.32
Q4 24
$-63.64
Q3 24
$-15.75
Q2 24
$-16.73
Q1 24
$-1.31
$-0.28

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
BBLG
BBLG
SPRB
SPRB
Cash + ST InvestmentsLiquidity on hand
$48.9M
Total DebtLower is stronger
Stockholders' EquityBook value
$3.7M
$42.5M
Total Assets
$3.8M
$53.0M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
BBLG
BBLG
SPRB
SPRB
Q4 25
$48.9M
Q3 25
$10.7M
Q2 25
$16.4M
Q1 25
$25.6M
Q4 24
$38.8M
Q3 24
$60.1M
Q2 24
$69.7M
Q1 24
$81.2M
Total Debt
BBLG
BBLG
SPRB
SPRB
Q4 25
Q3 25
$549.0K
Q2 25
$972.0K
Q1 25
$1.4M
Q4 24
$1.8M
Q3 24
$2.3M
Q2 24
$2.8M
Q1 24
$3.2M
Stockholders' Equity
BBLG
BBLG
SPRB
SPRB
Q4 25
$42.5M
Q3 25
$5.4M
Q2 25
$13.2M
Q1 25
$15.3M
Q4 24
$28.8M
Q3 24
$51.6M
Q2 24
$59.2M
Q1 24
$3.7M
$66.6M
Total Assets
BBLG
BBLG
SPRB
SPRB
Q4 25
$53.0M
Q3 25
$15.3M
Q2 25
$21.8M
Q1 25
$31.6M
Q4 24
$45.2M
Q3 24
$65.1M
Q2 24
$75.5M
Q1 24
$3.8M
$87.5M
Debt / Equity
BBLG
BBLG
SPRB
SPRB
Q4 25
Q3 25
0.10×
Q2 25
0.07×
Q1 25
0.09×
Q4 24
0.06×
Q3 24
0.04×
Q2 24
0.05×
Q1 24
0.05×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
BBLG
BBLG
SPRB
SPRB
Operating Cash FlowLast quarter
$-1.3M
$-6.5M
Free Cash FlowOCF − Capex
FCF MarginFCF / Revenue
Capex IntensityCapex / Revenue
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
BBLG
BBLG
SPRB
SPRB
Q4 25
$-6.5M
Q3 25
$-5.3M
Q2 25
$-8.8M
Q1 25
$-12.7M
Q4 24
$-20.7M
Q3 24
$-9.2M
Q2 24
$-11.1M
Q1 24
$-1.3M
$-15.0M

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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