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Side-by-side financial comparison of BIOCRYST PHARMACEUTICALS INC (BCRX) and OPAL Fuels Inc. (OPAL). Click either name above to swap in a different company.

BIOCRYST PHARMACEUTICALS INC is the larger business by last-quarter revenue ($156.4M vs $88.4M, roughly 1.8× OPAL Fuels Inc.). On growth, OPAL Fuels Inc. posted the faster year-over-year revenue change (18.7% vs 7.5%). Over the past eight quarters, BIOCRYST PHARMACEUTICALS INC's revenue compounded faster (19.6% CAGR vs 17.6%).

BioCryst Pharmaceuticals, Inc. is an American pharmaceutical company headquartered in Durham, North Carolina. The company is a late stage biotech company that focuses on oral drugs for rare and serious diseases. BioCryst's antiviral drug peramivir (Rapivab) was approved by FDA in December 2014. It has also been approved in Japan, Korea, and China.

OPAL Fuels Inc. is a North American energy company focused on producing and distributing low-carbon renewable natural gas (RNG). It captures methane from landfills, dairy operations and other organic waste streams to produce RNG, which is mainly supplied to heavy-duty transportation fleets, commercial logistics operators and public transport entities to help reduce their greenhouse gas emissions.

BCRX vs OPAL — Head-to-Head

Bigger by revenue
BCRX
BCRX
1.8× larger
BCRX
$156.4M
$88.4M
OPAL
Growing faster (revenue YoY)
OPAL
OPAL
+11.3% gap
OPAL
18.7%
7.5%
BCRX
Faster 2-yr revenue CAGR
BCRX
BCRX
Annualised
BCRX
19.6%
17.6%
OPAL

Income Statement — Q1 FY2026 vs Q4 FY2025

Metric
BCRX
BCRX
OPAL
OPAL
Revenue
$156.4M
$88.4M
Net Profit
$16.2M
Gross Margin
Operating Margin
13.6%
7.5%
Net Margin
18.3%
Revenue YoY
7.5%
18.7%
Net Profit YoY
401.5%
EPS (diluted)
$0.00
$0.08

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
BCRX
BCRX
OPAL
OPAL
Q1 26
$156.4M
Q4 25
$406.6M
$88.4M
Q3 25
$159.4M
$77.9M
Q2 25
$163.4M
$77.4M
Q1 25
$145.5M
$83.0M
Q4 24
$131.5M
$74.5M
Q3 24
$117.1M
$82.6M
Q2 24
$109.3M
$69.8M
Net Profit
BCRX
BCRX
OPAL
OPAL
Q1 26
Q4 25
$245.8M
$16.2M
Q3 25
$12.9M
$11.4M
Q2 25
$5.1M
$7.6M
Q1 25
$32.0K
$1.3M
Q4 24
$-26.8M
$-5.4M
Q3 24
$-14.0M
$17.1M
Q2 24
$-12.7M
$1.9M
Gross Margin
BCRX
BCRX
OPAL
OPAL
Q1 26
Q4 25
97.7%
Q3 25
98.6%
Q2 25
98.3%
Q1 25
96.9%
Q4 24
95.4%
Q3 24
97.3%
Q2 24
98.4%
Operating Margin
BCRX
BCRX
OPAL
OPAL
Q1 26
13.6%
Q4 25
64.0%
7.5%
Q3 25
18.6%
4.6%
Q2 25
18.2%
-1.1%
Q1 25
14.6%
-2.3%
Q4 24
-3.4%
-0.5%
Q3 24
6.6%
14.9%
Q2 24
8.0%
8.1%
Net Margin
BCRX
BCRX
OPAL
OPAL
Q1 26
Q4 25
60.5%
18.3%
Q3 25
8.1%
14.6%
Q2 25
3.1%
9.8%
Q1 25
0.0%
1.5%
Q4 24
-20.4%
-7.2%
Q3 24
-12.0%
20.7%
Q2 24
-11.6%
2.7%
EPS (diluted)
BCRX
BCRX
OPAL
OPAL
Q1 26
$0.00
Q4 25
$1.13
$0.08
Q3 25
$0.06
$0.05
Q2 25
$0.02
$0.03
Q1 25
$0.00
$-0.01
Q4 24
$-0.13
$-0.05
Q3 24
$-0.07
$0.09
Q2 24
$-0.06
$-0.01

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
BCRX
BCRX
OPAL
OPAL
Cash + ST InvestmentsLiquidity on hand
$259.0M
$24.4M
Total DebtLower is stronger
$361.3M
Stockholders' EquityBook value
$-12.9M
Total Assets
$465.1M
$959.5M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
BCRX
BCRX
OPAL
OPAL
Q1 26
$259.0M
Q4 25
$274.7M
$24.4M
Q3 25
$212.9M
$29.9M
Q2 25
$260.0M
$29.3M
Q1 25
$295.1M
$40.1M
Q4 24
$320.9M
$24.3M
Q3 24
$96.8M
$31.0M
Q2 24
$78.4M
$27.6M
Total Debt
BCRX
BCRX
OPAL
OPAL
Q1 26
Q4 25
$361.3M
Q3 25
$351.2M
Q2 25
$331.6M
Q1 25
$307.0M
Q4 24
$307.5M
Q3 24
$252.9M
Q2 24
$233.3M
Stockholders' Equity
BCRX
BCRX
OPAL
OPAL
Q1 26
Q4 25
$-119.2M
$-12.9M
Q3 25
$-387.9M
$7.5M
Q2 25
$-421.6M
$-25.0M
Q1 25
$-451.9M
$57.1M
Q4 24
$-475.9M
$-148.4M
Q3 24
$-468.6M
$-180.1M
Q2 24
$-475.6M
$-273.0M
Total Assets
BCRX
BCRX
OPAL
OPAL
Q1 26
$465.1M
Q4 25
$514.2M
$959.5M
Q3 25
$446.4M
$916.7M
Q2 25
$457.2M
$905.5M
Q1 25
$480.0M
$884.9M
Q4 24
$490.4M
$881.1M
Q3 24
$491.3M
$831.1M
Q2 24
$472.4M
$782.3M
Debt / Equity
BCRX
BCRX
OPAL
OPAL
Q1 26
Q4 25
Q3 25
46.95×
Q2 25
Q1 25
5.38×
Q4 24
Q3 24
Q2 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
BCRX
BCRX
OPAL
OPAL
Operating Cash FlowLast quarter
$-3.5M
Free Cash FlowOCF − Capex
$-13.4M
FCF MarginFCF / Revenue
-15.1%
Capex IntensityCapex / Revenue
11.1%
Cash ConversionOCF / Net Profit
-0.22×
TTM Free Cash FlowTrailing 4 quarters
$-34.2M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
BCRX
BCRX
OPAL
OPAL
Q1 26
Q4 25
$292.0M
$-3.5M
Q3 25
$41.6M
$18.2M
Q2 25
$41.3M
$-7.9M
Q1 25
$-27.5M
$29.7M
Q4 24
$-5.2M
$-532.0K
Q3 24
$8.2M
$17.7M
Q2 24
$-1.4M
$533.0K
Free Cash Flow
BCRX
BCRX
OPAL
OPAL
Q1 26
Q4 25
$291.2M
$-13.4M
Q3 25
$40.3M
$-9.3M
Q2 25
$41.1M
$-29.7M
Q1 25
$-27.7M
$18.1M
Q4 24
$-5.9M
$-55.0M
Q3 24
$8.2M
$-5.4M
Q2 24
$-1.5M
$-22.5M
FCF Margin
BCRX
BCRX
OPAL
OPAL
Q1 26
Q4 25
71.6%
-15.1%
Q3 25
25.3%
-11.9%
Q2 25
25.2%
-38.4%
Q1 25
-19.0%
21.8%
Q4 24
-4.5%
-73.8%
Q3 24
7.0%
-6.5%
Q2 24
-1.4%
-32.2%
Capex Intensity
BCRX
BCRX
OPAL
OPAL
Q1 26
Q4 25
0.2%
11.1%
Q3 25
0.8%
35.3%
Q2 25
0.1%
28.2%
Q1 25
0.1%
13.9%
Q4 24
0.5%
73.1%
Q3 24
0.1%
27.9%
Q2 24
0.1%
32.9%
Cash Conversion
BCRX
BCRX
OPAL
OPAL
Q1 26
Q4 25
1.19×
-0.22×
Q3 25
3.23×
1.60×
Q2 25
8.12×
-1.04×
Q1 25
-859.91×
23.11×
Q4 24
Q3 24
1.03×
Q2 24
0.28×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

BCRX
BCRX

ORLADEYO$148.3M95%
Other revenues$5.0M3%
License revenue$3.0M2%

OPAL
OPAL

Fuel Station Services Segment$65.1M74%
Related Party$12.1M14%
Renewable Power Segment$8.6M10%
Other$2.6M3%

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