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Side-by-side financial comparison of BIOCRYST PHARMACEUTICALS INC (BCRX) and OCTAVE SPECIALTY GROUP INC (OSG). Click either name above to swap in a different company.

BIOCRYST PHARMACEUTICALS INC is the larger business by last-quarter revenue ($156.4M vs $104.2M, roughly 1.5× OCTAVE SPECIALTY GROUP INC). On growth, OCTAVE SPECIALTY GROUP INC posted the faster year-over-year revenue change (66.0% vs 7.5%). Over the past eight quarters, OCTAVE SPECIALTY GROUP INC's revenue compounded faster (42.9% CAGR vs 19.6%).

BioCryst Pharmaceuticals, Inc. is an American pharmaceutical company headquartered in Durham, North Carolina. The company is a late stage biotech company that focuses on oral drugs for rare and serious diseases. BioCryst's antiviral drug peramivir (Rapivab) was approved by FDA in December 2014. It has also been approved in Japan, Korea, and China.

Octave Specialty Group Inc. is a specialty insurance holding company that provides tailored property and casualty insurance products. Its core business focuses on excess and surplus lines, catering to commercial and individual clients across primary North American markets with customized risk coverage solutions.

BCRX vs OSG — Head-to-Head

Bigger by revenue
BCRX
BCRX
1.5× larger
BCRX
$156.4M
$104.2M
OSG
Growing faster (revenue YoY)
OSG
OSG
+58.5% gap
OSG
66.0%
7.5%
BCRX
Faster 2-yr revenue CAGR
OSG
OSG
Annualised
OSG
42.9%
19.6%
BCRX

Income Statement — Q1 FY2026 vs Q1 FY2026

Metric
BCRX
BCRX
OSG
OSG
Revenue
$156.4M
$104.2M
Net Profit
$-6.9M
Gross Margin
Operating Margin
13.6%
Net Margin
-6.6%
Revenue YoY
7.5%
66.0%
Net Profit YoY
EPS (diluted)
$0.00
$-0.13

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
BCRX
BCRX
OSG
OSG
Q1 26
$156.4M
$104.2M
Q4 25
$406.6M
$66.9M
Q3 25
$159.4M
$66.6M
Q2 25
$163.4M
$55.0M
Q1 25
$145.5M
$62.8M
Q4 24
$131.5M
$65.2M
Q3 24
$117.1M
$70.0M
Q2 24
$109.3M
$51.0M
Net Profit
BCRX
BCRX
OSG
OSG
Q1 26
$-6.9M
Q4 25
$245.8M
$-29.7M
Q3 25
$12.9M
$-112.6M
Q2 25
$5.1M
$-72.7M
Q1 25
$32.0K
$-44.7M
Q4 24
$-26.8M
$-20.9M
Q3 24
$-14.0M
$-27.5M
Q2 24
$-12.7M
$-750.0K
Gross Margin
BCRX
BCRX
OSG
OSG
Q1 26
Q4 25
97.7%
Q3 25
98.6%
Q2 25
98.3%
Q1 25
96.9%
Q4 24
95.4%
Q3 24
97.3%
Q2 24
98.4%
Operating Margin
BCRX
BCRX
OSG
OSG
Q1 26
13.6%
Q4 25
64.0%
-76.7%
Q3 25
18.6%
-48.2%
Q2 25
18.2%
-41.8%
Q1 25
14.6%
-24.1%
Q4 24
-3.4%
-55.5%
Q3 24
6.6%
-29.7%
Q2 24
8.0%
-28.9%
Net Margin
BCRX
BCRX
OSG
OSG
Q1 26
-6.6%
Q4 25
60.5%
-73.8%
Q3 25
8.1%
-169.1%
Q2 25
3.1%
-132.3%
Q1 25
0.0%
-71.3%
Q4 24
-20.4%
-55.1%
Q3 24
-12.0%
-39.3%
Q2 24
-11.6%
-1.5%
EPS (diluted)
BCRX
BCRX
OSG
OSG
Q1 26
$0.00
$-0.13
Q4 25
$1.13
$-0.82
Q3 25
$0.06
$-2.35
Q2 25
$0.02
$-1.54
Q1 25
$0.00
$-1.22
Q4 24
$-0.13
$-11.75
Q3 24
$-0.07
$-0.63
Q2 24
$-0.06
$-0.02

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
BCRX
BCRX
OSG
OSG
Cash + ST InvestmentsLiquidity on hand
$259.0M
Total DebtLower is stronger
$117.1M
Stockholders' EquityBook value
$833.6M
Total Assets
$465.1M
$2.3B
Debt / EquityLower = less leverage
0.14×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
BCRX
BCRX
OSG
OSG
Q1 26
$259.0M
Q4 25
$274.7M
$146.4M
Q3 25
$212.9M
$27.5M
Q2 25
$260.0M
$22.5M
Q1 25
$295.1M
$34.1M
Q4 24
$320.9M
$157.2M
Q3 24
$96.8M
$40.8M
Q2 24
$78.4M
$14.6M
Total Debt
BCRX
BCRX
OSG
OSG
Q1 26
$117.1M
Q4 25
$117.6M
Q3 25
Q2 25
Q1 25
Q4 24
$0
Q3 24
$518.0M
Q2 24
$515.0M
Stockholders' Equity
BCRX
BCRX
OSG
OSG
Q1 26
$833.6M
Q4 25
$-119.2M
$715.8M
Q3 25
$-387.9M
$843.4M
Q2 25
$-421.6M
$859.8M
Q1 25
$-451.9M
$852.2M
Q4 24
$-475.9M
$798.4M
Q3 24
$-468.6M
$1.5B
Q2 24
$-475.6M
$1.4B
Total Assets
BCRX
BCRX
OSG
OSG
Q1 26
$465.1M
$2.3B
Q4 25
$514.2M
$2.2B
Q3 25
$446.4M
$2.1B
Q2 25
$457.2M
$8.5B
Q1 25
$480.0M
$8.3B
Q4 24
$490.4M
$8.1B
Q3 24
$491.3M
$9.3B
Q2 24
$472.4M
$8.2B
Debt / Equity
BCRX
BCRX
OSG
OSG
Q1 26
0.14×
Q4 25
0.16×
Q3 25
Q2 25
Q1 25
Q4 24
0.00×
Q3 24
0.35×
Q2 24
0.38×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

BCRX
BCRX

ORLADEYO$148.3M95%
Other revenues$5.0M3%
License revenue$3.0M2%

OSG
OSG

Commissions$68.2M65%
Other$20.6M20%
Servicing and other fees$9.4M9%
Program fees$3.6M3%
Investment income$2.4M2%

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