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Side-by-side financial comparison of Biofrontera Inc. (BFRI) and Spok Holdings, Inc (SPOK). Click either name above to swap in a different company.

Spok Holdings, Inc is the larger business by last-quarter revenue ($33.9M vs $17.1M, roughly 2.0× Biofrontera Inc.). Biofrontera Inc. runs the higher net margin — 33.0% vs 8.7%, a 24.3% gap on every dollar of revenue. On growth, Biofrontera Inc. posted the faster year-over-year revenue change (36.2% vs -0.1%). Spok Holdings, Inc produced more free cash flow last quarter ($10.1M vs $-2.4M). Over the past eight quarters, Biofrontera Inc.'s revenue compounded faster (47.0% CAGR vs -1.5%).

Biofrontera Inc. is a specialty biopharmaceutical enterprise focused on developing and commercializing prescription dermatological products. Its core product line targets skin conditions including actinic keratosis and other dermatological disorders, with primary operating markets in the United States and European Union, serving patients and dermatology care providers.

Spok Holdings, Inc. is a global provider of critical communication solutions primarily serving the healthcare industry. It offers unified clinical communication platforms, secure messaging tools, alerting systems, and on-call scheduling software that help care teams coordinate efficiently, cut response times, and boost patient safety across medical facilities.

BFRI vs SPOK — Head-to-Head

Bigger by revenue
SPOK
SPOK
2.0× larger
SPOK
$33.9M
$17.1M
BFRI
Growing faster (revenue YoY)
BFRI
BFRI
+36.3% gap
BFRI
36.2%
-0.1%
SPOK
Higher net margin
BFRI
BFRI
24.3% more per $
BFRI
33.0%
8.7%
SPOK
More free cash flow
SPOK
SPOK
$12.5M more FCF
SPOK
$10.1M
$-2.4M
BFRI
Faster 2-yr revenue CAGR
BFRI
BFRI
Annualised
BFRI
47.0%
-1.5%
SPOK

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
BFRI
BFRI
SPOK
SPOK
Revenue
$17.1M
$33.9M
Net Profit
$5.6M
$2.9M
Gross Margin
76.7%
Operating Margin
26.6%
11.6%
Net Margin
33.0%
8.7%
Revenue YoY
36.2%
-0.1%
Net Profit YoY
504.0%
-19.6%
EPS (diluted)
$0.62
$0.13

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
BFRI
BFRI
SPOK
SPOK
Q4 25
$17.1M
$33.9M
Q3 25
$7.0M
$33.9M
Q2 25
$9.0M
$35.7M
Q1 25
$8.6M
$36.3M
Q4 24
$12.6M
$33.9M
Q3 24
$9.0M
$34.9M
Q2 24
$7.8M
$34.0M
Q1 24
$7.9M
$34.9M
Net Profit
BFRI
BFRI
SPOK
SPOK
Q4 25
$5.6M
$2.9M
Q3 25
$-6.6M
$3.2M
Q2 25
$-5.3M
$4.6M
Q1 25
$-4.2M
$5.2M
Q4 24
$-1.4M
$3.6M
Q3 24
$-5.7M
$3.7M
Q2 24
$-257.0K
$3.4M
Q1 24
$-10.4M
$4.2M
Gross Margin
BFRI
BFRI
SPOK
SPOK
Q4 25
76.7%
Q3 25
78.3%
Q2 25
79.5%
Q1 25
80.1%
Q4 24
78.5%
Q3 24
79.5%
Q2 24
78.9%
Q1 24
79.5%
Operating Margin
BFRI
BFRI
SPOK
SPOK
Q4 25
26.6%
11.6%
Q3 25
-89.8%
12.9%
Q2 25
-56.2%
15.1%
Q1 25
-52.9%
16.6%
Q4 24
-13.6%
13.7%
Q3 24
-55.0%
14.2%
Q2 24
-64.7%
13.2%
Q1 24
-69.1%
14.0%
Net Margin
BFRI
BFRI
SPOK
SPOK
Q4 25
33.0%
8.7%
Q3 25
-95.1%
9.5%
Q2 25
-59.0%
12.8%
Q1 25
-48.9%
14.3%
Q4 24
-11.1%
10.8%
Q3 24
-62.9%
10.5%
Q2 24
-3.3%
10.1%
Q1 24
-131.9%
12.1%
EPS (diluted)
BFRI
BFRI
SPOK
SPOK
Q4 25
$0.62
$0.13
Q3 25
$-0.62
$0.15
Q2 25
$-0.57
$0.22
Q1 25
$-0.47
$0.25
Q4 24
$0.69
$0.17
Q3 24
$-0.98
$0.18
Q2 24
$-0.05
$0.17
Q1 24
$-2.88
$0.21

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
BFRI
BFRI
SPOK
SPOK
Cash + ST InvestmentsLiquidity on hand
$6.4M
$25.3M
Total DebtLower is stronger
Stockholders' EquityBook value
$10.5M
$146.4M
Total Assets
$28.6M
$206.1M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
BFRI
BFRI
SPOK
SPOK
Q4 25
$6.4M
$25.3M
Q3 25
$3.4M
$21.4M
Q2 25
$7.2M
$20.2M
Q1 25
$1.8M
$19.9M
Q4 24
$5.9M
$29.1M
Q3 24
$2.9M
$27.8M
Q2 24
$4.4M
$23.9M
Q1 24
$3.8M
$23.3M
Stockholders' Equity
BFRI
BFRI
SPOK
SPOK
Q4 25
$10.5M
$146.4M
Q3 25
$-2.6M
$148.7M
Q2 25
$-4.7M
$150.9M
Q1 25
$500.0K
$151.7M
Q4 24
$4.4M
$154.7M
Q3 24
$5.5M
$156.3M
Q2 24
$10.9M
$158.2M
Q1 24
$-5.4M
$160.2M
Total Assets
BFRI
BFRI
SPOK
SPOK
Q4 25
$28.6M
$206.1M
Q3 25
$15.4M
$209.7M
Q2 25
$20.1M
$208.7M
Q1 25
$16.6M
$204.5M
Q4 24
$22.1M
$217.1M
Q3 24
$18.5M
$216.8M
Q2 24
$21.6M
$216.4M
Q1 24
$24.6M
$215.0M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
BFRI
BFRI
SPOK
SPOK
Operating Cash FlowLast quarter
$-2.4M
$11.5M
Free Cash FlowOCF − Capex
$-2.4M
$10.1M
FCF MarginFCF / Revenue
-13.9%
29.9%
Capex IntensityCapex / Revenue
0.0%
4.1%
Cash ConversionOCF / Net Profit
-0.42×
3.93×
TTM Free Cash FlowTrailing 4 quarters
$-13.4M
$25.2M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
BFRI
BFRI
SPOK
SPOK
Q4 25
$-2.4M
$11.5M
Q3 25
$-3.8M
$8.1M
Q2 25
$-3.0M
$7.0M
Q1 25
$-4.1M
$2.3M
Q4 24
$-1.0M
$8.4M
Q3 24
$-1.2M
$11.1M
Q2 24
$-4.7M
$7.4M
Q1 24
$-3.3M
$2.0M
Free Cash Flow
BFRI
BFRI
SPOK
SPOK
Q4 25
$-2.4M
$10.1M
Q3 25
$-3.8M
$7.6M
Q2 25
$-3.0M
$6.0M
Q1 25
$-4.1M
$1.5M
Q4 24
$-1.0M
$7.5M
Q3 24
$10.3M
Q2 24
$-4.8M
$6.8M
Q1 24
$-3.4M
$1.1M
FCF Margin
BFRI
BFRI
SPOK
SPOK
Q4 25
-13.9%
29.9%
Q3 25
-54.7%
22.4%
Q2 25
-33.7%
16.8%
Q1 25
-48.0%
4.2%
Q4 24
-8.1%
22.3%
Q3 24
29.4%
Q2 24
-60.8%
20.0%
Q1 24
-42.7%
3.2%
Capex Intensity
BFRI
BFRI
SPOK
SPOK
Q4 25
0.0%
4.1%
Q3 25
0.0%
1.6%
Q2 25
0.0%
2.9%
Q1 25
0.0%
2.1%
Q4 24
0.0%
2.5%
Q3 24
0.0%
2.4%
Q2 24
0.6%
1.9%
Q1 24
0.7%
2.5%
Cash Conversion
BFRI
BFRI
SPOK
SPOK
Q4 25
-0.42×
3.93×
Q3 25
2.54×
Q2 25
1.55×
Q1 25
0.43×
Q4 24
2.31×
Q3 24
3.03×
Q2 24
2.17×
Q1 24
0.47×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

BFRI
BFRI

Segment breakdown not available.

SPOK
SPOK

Paging$16.8M50%
Software Operations$16.0M47%
License$1.2M4%

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