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Side-by-side financial comparison of Biogen (BIIB) and CME Group (CME). Click either name above to swap in a different company.
Biogen is the larger business by last-quarter revenue ($2.3B vs $1.9B, roughly 1.2× CME Group). CME Group runs the higher net margin — 0.1% vs -2.1%, a 2.2% gap on every dollar of revenue. On growth, CME Group posted the faster year-over-year revenue change (14.5% vs -7.1%). Over the past eight quarters, CME Group's revenue compounded faster (10.8% CAGR vs -0.2%).
Biogen Inc. is an American multinational biotechnology company based in Cambridge, Massachusetts, United States specializing in the treatment of neurological diseases. The company's primary products are dimethyl fumarate (Tecfidera), diroximel fumarate (Vumerity), interferon beta-1a (AVONEX), peginterferon beta-1a (Plegridy), and natalizumab (Tysabri), all for the treatment of multiple sclerosis ; nusinersen (Spinraza) for the treatment of spinal muscular atrophy ; omaveloxolone (Skyclarys) for ...
CME Group Inc. is an American financial services company based in Chicago, Illinois. It operates financial derivatives exchanges, including the Chicago Mercantile Exchange (CME), the Chicago Board of Trade (CBOT), the New York Mercantile Exchange (NYMEX), and the Commodity Exchange (COMEX). The company owns 27% of S&P Dow Jones Indices. It is the world's largest operator of financial derivatives exchanges. Its exchanges are platforms for trading in agricultural products, currencies, energy, i...
BIIB vs CME — Head-to-Head
Income Statement — Q4 FY2025 vs Q1 FY2026
| Metric | | |
|---|---|---|
| Revenue | $2.3B | $1.9B |
| Net Profit | $-48.9M | $1.2M |
| Gross Margin | 78.3% | — |
| Operating Margin | -2.5% | 0.1% |
| Net Margin | -2.1% | 0.1% |
| Revenue YoY | -7.1% | 14.5% |
| Net Profit YoY | -118.3% | 20.7% |
| EPS (diluted) | $-0.35 | — |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q1 26 | — | $1.9B | ||
| Q4 25 | $2.3B | $1.6B | ||
| Q3 25 | $2.5B | $1.5B | ||
| Q2 25 | $2.6B | $1.7B | ||
| Q1 25 | $2.4B | $1.6B | ||
| Q4 24 | $2.5B | $1.5B | ||
| Q3 24 | $2.5B | $1.6B | ||
| Q2 24 | $2.5B | $1.5B |
| Q1 26 | — | $1.2M | ||
| Q4 25 | $-48.9M | $1.2B | ||
| Q3 25 | $466.5M | $908.0M | ||
| Q2 25 | $634.8M | $1.0B | ||
| Q1 25 | $240.5M | $956.2M | ||
| Q4 24 | $266.7M | $874.6M | ||
| Q3 24 | $388.5M | $912.8M | ||
| Q2 24 | $583.6M | $883.2M |
| Q1 26 | — | — | ||
| Q4 25 | 78.3% | — | ||
| Q3 25 | 73.4% | — | ||
| Q2 25 | 77.1% | — | ||
| Q1 25 | 74.1% | — | ||
| Q4 24 | 76.2% | — | ||
| Q3 24 | 74.1% | — | ||
| Q2 24 | 77.8% | — |
| Q1 26 | — | 0.1% | ||
| Q4 25 | -2.5% | 61.8% | ||
| Q3 25 | 22.0% | 63.3% | ||
| Q2 25 | 28.1% | 66.7% | ||
| Q1 25 | 12.8% | 67.5% | ||
| Q4 24 | 11.9% | 62.1% | ||
| Q3 24 | 18.3% | 64.6% | ||
| Q2 24 | 28.3% | 65.3% |
| Q1 26 | — | 0.1% | ||
| Q4 25 | -2.1% | 71.7% | ||
| Q3 25 | 18.4% | 59.1% | ||
| Q2 25 | 24.0% | 60.6% | ||
| Q1 25 | 9.9% | 58.2% | ||
| Q4 24 | 10.9% | 57.3% | ||
| Q3 24 | 15.8% | 57.6% | ||
| Q2 24 | 23.7% | 57.6% |
| Q1 26 | — | — | ||
| Q4 25 | $-0.35 | $3.24 | ||
| Q3 25 | $3.17 | $2.49 | ||
| Q2 25 | $4.33 | $2.81 | ||
| Q1 25 | $1.64 | $2.62 | ||
| Q4 24 | $1.82 | $2.40 | ||
| Q3 24 | $2.66 | $2.50 | ||
| Q2 24 | $4.00 | $2.42 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | — | $2.4B |
| Total DebtLower is stronger | $6.3B | $3.4B |
| Stockholders' EquityBook value | $18.3B | — |
| Total Assets | $29.4B | $202.0B |
| Debt / EquityLower = less leverage | 0.34× | — |
8-quarter trend — quarters aligned by calendar period.
| Q1 26 | — | $2.4B | ||
| Q4 25 | — | $4.5B | ||
| Q3 25 | — | $2.6B | ||
| Q2 25 | — | $2.1B | ||
| Q1 25 | — | $1.5B | ||
| Q4 24 | — | $3.0B | ||
| Q3 24 | — | $2.4B | ||
| Q2 24 | — | $1.9B |
| Q1 26 | — | $3.4B | ||
| Q4 25 | $6.3B | — | ||
| Q3 25 | $6.3B | — | ||
| Q2 25 | $6.3B | — | ||
| Q1 25 | $4.5B | — | ||
| Q4 24 | $6.3B | — | ||
| Q3 24 | $4.5B | — | ||
| Q2 24 | $6.3B | — |
| Q1 26 | — | — | ||
| Q4 25 | $18.3B | $28.7B | ||
| Q3 25 | $18.2B | $28.2B | ||
| Q2 25 | $17.6B | $27.7B | ||
| Q1 25 | $17.0B | $27.0B | ||
| Q4 24 | $16.7B | $26.5B | ||
| Q3 24 | $16.4B | $28.2B | ||
| Q2 24 | $15.9B | $27.6B |
| Q1 26 | — | $202.0B | ||
| Q4 25 | $29.4B | $198.4B | ||
| Q3 25 | $29.2B | $187.1B | ||
| Q2 25 | $28.3B | $179.9B | ||
| Q1 25 | $28.0B | $157.8B | ||
| Q4 24 | $28.0B | $137.4B | ||
| Q3 24 | $28.3B | $137.8B | ||
| Q2 24 | $26.8B | $123.4B |
| Q1 26 | — | — | ||
| Q4 25 | 0.34× | — | ||
| Q3 25 | 0.35× | — | ||
| Q2 25 | 0.36× | — | ||
| Q1 25 | 0.27× | — | ||
| Q4 24 | 0.38× | — | ||
| Q3 24 | 0.28× | — | ||
| Q2 24 | 0.40× | — |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $511.9M | — |
| Free Cash FlowOCF − Capex | $468.0M | — |
| FCF MarginFCF / Revenue | 20.5% | — |
| Capex IntensityCapex / Revenue | 1.9% | — |
| Cash ConversionOCF / Net Profit | — | — |
| TTM Free Cash FlowTrailing 4 quarters | $2.1B | — |
8-quarter trend — quarters aligned by calendar period.
| Q1 26 | — | — | ||
| Q4 25 | $511.9M | $1.1B | ||
| Q3 25 | $1.3B | $968.1M | ||
| Q2 25 | $160.9M | $1.1B | ||
| Q1 25 | $259.3M | $1.1B | ||
| Q4 24 | $760.9M | $1.0B | ||
| Q3 24 | $935.6M | $1.0B | ||
| Q2 24 | $625.8M | $776.9M |
| Q1 26 | — | — | ||
| Q4 25 | $468.0M | $1.1B | ||
| Q3 25 | $1.2B | $949.7M | ||
| Q2 25 | $134.3M | $1.0B | ||
| Q1 25 | $222.2M | $1.1B | ||
| Q4 24 | $721.6M | $991.7M | ||
| Q3 24 | $900.6M | $973.2M | ||
| Q2 24 | $592.3M | $758.7M |
| Q1 26 | — | — | ||
| Q4 25 | 20.5% | 66.8% | ||
| Q3 25 | 48.4% | 61.8% | ||
| Q2 25 | 5.1% | 61.5% | ||
| Q1 25 | 9.1% | 67.1% | ||
| Q4 24 | 29.4% | 65.0% | ||
| Q3 24 | 36.5% | 61.4% | ||
| Q2 24 | 24.0% | 49.5% |
| Q1 26 | — | — | ||
| Q4 25 | 1.9% | 2.0% | ||
| Q3 25 | 1.8% | 1.2% | ||
| Q2 25 | 1.0% | 1.1% | ||
| Q1 25 | 1.5% | 0.9% | ||
| Q4 24 | 1.6% | 1.7% | ||
| Q3 24 | 1.4% | 1.9% | ||
| Q2 24 | 1.4% | 1.2% |
| Q1 26 | — | — | ||
| Q4 25 | — | 0.96× | ||
| Q3 25 | 2.73× | 1.07× | ||
| Q2 25 | 0.25× | 1.03× | ||
| Q1 25 | 1.08× | 1.17× | ||
| Q4 24 | 2.85× | 1.16× | ||
| Q3 24 | 2.41× | 1.10× | ||
| Q2 24 | 1.07× | 0.88× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
BIIB
| Products | $1.7B | 73% |
| Tysabri Product | $244.5M | 11% |
| AVONEX | $119.2M | 5% |
| SKYCLARYS | $88.9M | 4% |
| Alzheimers Collaboration | $47.1M | 2% |
| IMRALDI | $43.5M | 2% |
| TECFIDERA | $36.9M | 2% |
| PLEGRIDY | $24.7M | 1% |
| QALSODY | $7.8M | 0% |
| BYOOVIZ | $4.3M | 0% |
CME
Segment breakdown not available.
