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Side-by-side financial comparison of BIOLIFE SOLUTIONS INC (BLFS) and OptimizeRx Corp (OPRX). Click either name above to swap in a different company.

OptimizeRx Corp is the larger business by last-quarter revenue ($32.2M vs $18.8M, roughly 1.7× BIOLIFE SOLUTIONS INC). BIOLIFE SOLUTIONS INC runs the higher net margin — 58.9% vs 15.6%, a 43.4% gap on every dollar of revenue. On growth, BIOLIFE SOLUTIONS INC posted the faster year-over-year revenue change (24.3% vs -0.2%). Over the past eight quarters, OptimizeRx Corp's revenue compounded faster (28.0% CAGR vs 1.0%).

Biolife Solutions Inc. develops, manufactures and distributes specialized biopreservation products and cold chain management solutions for the cell and gene therapy, biopharmaceutical and regenerative medicine industries. It offers cryopreservation media, automated thawing systems, and temperature monitoring tools, serving biotech firms, research institutions and clinical labs globally.

OptimizeRx Corp is a U.S.-headquartered digital health technology company that delivers patient engagement, medication affordability and clinical communication solutions to life sciences enterprises, healthcare providers and pharmacy partners. Its core offerings include digital medication savings tools, patient support programs, and therapeutic area-specific resources to boost medication access and treatment adherence.

BLFS vs OPRX — Head-to-Head

Bigger by revenue
OPRX
OPRX
1.7× larger
OPRX
$32.2M
$18.8M
BLFS
Growing faster (revenue YoY)
BLFS
BLFS
+24.6% gap
BLFS
24.3%
-0.2%
OPRX
Higher net margin
BLFS
BLFS
43.4% more per $
BLFS
58.9%
15.6%
OPRX
Faster 2-yr revenue CAGR
OPRX
OPRX
Annualised
OPRX
28.0%
1.0%
BLFS

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
BLFS
BLFS
OPRX
OPRX
Revenue
$18.8M
$32.2M
Net Profit
$11.1M
$5.0M
Gross Margin
74.8%
Operating Margin
7.2%
26.6%
Net Margin
58.9%
15.6%
Revenue YoY
24.3%
-0.2%
Net Profit YoY
-11.1%
6535.9%
EPS (diluted)
$0.23
$0.27

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
BLFS
BLFS
OPRX
OPRX
Q4 25
$18.8M
$32.2M
Q3 25
$28.1M
$26.1M
Q2 25
$25.4M
$29.2M
Q1 25
$23.9M
$21.9M
Q4 24
$15.1M
$32.3M
Q3 24
$21.4M
$21.3M
Q2 24
$19.7M
$18.8M
Q1 24
$18.4M
$19.7M
Net Profit
BLFS
BLFS
OPRX
OPRX
Q4 25
$11.1M
$5.0M
Q3 25
$621.0K
$779.0K
Q2 25
$-15.8M
$1.5M
Q1 25
$-448.0K
$-2.2M
Q4 24
$12.5M
$-78.0K
Q3 24
$-1.7M
$-9.1M
Q2 24
$-20.7M
$-4.0M
Q1 24
$-10.2M
$-6.9M
Gross Margin
BLFS
BLFS
OPRX
OPRX
Q4 25
74.8%
Q3 25
67.2%
Q2 25
63.8%
Q1 25
60.9%
Q4 24
68.1%
Q3 24
63.1%
Q2 24
62.2%
Q1 24
62.0%
Operating Margin
BLFS
BLFS
OPRX
OPRX
Q4 25
7.2%
26.6%
Q3 25
-0.3%
7.9%
Q2 25
-65.5%
10.9%
Q1 25
-5.1%
-9.6%
Q4 24
3.6%
11.2%
Q3 24
-2.0%
-40.2%
Q2 24
-6.6%
-19.9%
Q1 24
-17.9%
-25.5%
Net Margin
BLFS
BLFS
OPRX
OPRX
Q4 25
58.9%
15.6%
Q3 25
2.2%
3.0%
Q2 25
-62.3%
5.2%
Q1 25
-1.9%
-10.0%
Q4 24
82.5%
-0.2%
Q3 24
-8.0%
-42.8%
Q2 24
-105.1%
-21.3%
Q1 24
-55.4%
-35.0%
EPS (diluted)
BLFS
BLFS
OPRX
OPRX
Q4 25
$0.23
$0.27
Q3 25
$0.01
$0.04
Q2 25
$-0.33
$0.08
Q1 25
$-0.01
$-0.12
Q4 24
$0.27
$0.00
Q3 24
$-0.04
$-0.50
Q2 24
$-0.45
$-0.22
Q1 24
$-0.22
$-0.38

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
BLFS
BLFS
OPRX
OPRX
Cash + ST InvestmentsLiquidity on hand
$33.0M
$23.4M
Total DebtLower is stronger
$5.0M
$26.3M
Stockholders' EquityBook value
$371.9M
$128.3M
Total Assets
$405.9M
$176.9M
Debt / EquityLower = less leverage
0.01×
0.20×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
BLFS
BLFS
OPRX
OPRX
Q4 25
$33.0M
$23.4M
Q3 25
$29.5M
$19.5M
Q2 25
$31.9M
$16.6M
Q1 25
$66.9M
$16.6M
Q4 24
$91.5M
$13.4M
Q3 24
$24.0M
$16.1M
Q2 24
$22.0M
Q1 24
$29.7M
Total Debt
BLFS
BLFS
OPRX
OPRX
Q4 25
$5.0M
$26.3M
Q3 25
$7.5M
$28.8M
Q2 25
$10.1M
$29.3M
Q1 25
$12.9M
$33.8M
Q4 24
$15.9M
$34.3M
Q3 24
$20.1M
$36.8M
Q2 24
$21.1M
$37.3M
Q1 24
$24.3M
$37.8M
Stockholders' Equity
BLFS
BLFS
OPRX
OPRX
Q4 25
$371.9M
$128.3M
Q3 25
$353.7M
$122.3M
Q2 25
$347.2M
$119.3M
Q1 25
$352.6M
$116.3M
Q4 24
$348.9M
$117.0M
Q3 24
$325.5M
$114.5M
Q2 24
$321.4M
$121.0M
Q1 24
$333.4M
$122.5M
Total Assets
BLFS
BLFS
OPRX
OPRX
Q4 25
$405.9M
$176.9M
Q3 25
$392.1M
$170.3M
Q2 25
$387.2M
$169.3M
Q1 25
$395.1M
$167.8M
Q4 24
$399.5M
$171.2M
Q3 24
$381.7M
$165.2M
Q2 24
$375.0M
$172.9M
Q1 24
$401.6M
$176.4M
Debt / Equity
BLFS
BLFS
OPRX
OPRX
Q4 25
0.01×
0.20×
Q3 25
0.02×
0.24×
Q2 25
0.03×
0.25×
Q1 25
0.04×
0.29×
Q4 24
0.05×
0.29×
Q3 24
0.06×
0.32×
Q2 24
0.07×
0.31×
Q1 24
0.07×
0.31×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
BLFS
BLFS
OPRX
OPRX
Operating Cash FlowLast quarter
$4.9M
$7.1M
Free Cash FlowOCF − Capex
$7.1M
FCF MarginFCF / Revenue
22.0%
Capex IntensityCapex / Revenue
0.0%
Cash ConversionOCF / Net Profit
0.44×
1.41×
TTM Free Cash FlowTrailing 4 quarters
$18.7M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
BLFS
BLFS
OPRX
OPRX
Q4 25
$4.9M
$7.1M
Q3 25
$6.1M
$3.2M
Q2 25
$7.4M
$4.6M
Q1 25
$1.7M
$3.9M
Q4 24
$1.6M
$198.0K
Q3 24
$4.8M
$1.8M
Q2 24
$6.5M
$782.0K
Q1 24
$-4.5M
$2.1M
Free Cash Flow
BLFS
BLFS
OPRX
OPRX
Q4 25
$7.1M
Q3 25
$3.2M
Q2 25
$4.6M
Q1 25
$3.8M
Q4 24
$181.0K
Q3 24
$1.8M
Q2 24
$737.0K
Q1 24
$2.1M
FCF Margin
BLFS
BLFS
OPRX
OPRX
Q4 25
22.0%
Q3 25
12.2%
Q2 25
15.6%
Q1 25
17.5%
Q4 24
0.6%
Q3 24
8.3%
Q2 24
3.9%
Q1 24
10.6%
Capex Intensity
BLFS
BLFS
OPRX
OPRX
Q4 25
0.0%
Q3 25
0.0%
Q2 25
0.0%
Q1 25
0.1%
Q4 24
0.1%
Q3 24
0.1%
Q2 24
0.2%
Q1 24
0.2%
Cash Conversion
BLFS
BLFS
OPRX
OPRX
Q4 25
0.44×
1.41×
Q3 25
9.83×
4.11×
Q2 25
2.98×
Q1 25
Q4 24
0.13×
Q3 24
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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