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Side-by-side financial comparison of BIOLIFE SOLUTIONS INC (BLFS) and Spire Global, Inc. (SPIR). Click either name above to swap in a different company.

BIOLIFE SOLUTIONS INC is the larger business by last-quarter revenue ($18.8M vs $15.8M, roughly 1.2× Spire Global, Inc.). BIOLIFE SOLUTIONS INC runs the higher net margin — 58.9% vs -176.6%, a 235.6% gap on every dollar of revenue. On growth, BIOLIFE SOLUTIONS INC posted the faster year-over-year revenue change (24.3% vs -26.9%). Over the past eight quarters, BIOLIFE SOLUTIONS INC's revenue compounded faster (1.0% CAGR vs -32.6%).

Biolife Solutions Inc. develops, manufactures and distributes specialized biopreservation products and cold chain management solutions for the cell and gene therapy, biopharmaceutical and regenerative medicine industries. It offers cryopreservation media, automated thawing systems, and temperature monitoring tools, serving biotech firms, research institutions and clinical labs globally.

Spire Global, Inc. is a space-to-cloud data and analytics company that specializes in the tracking of global data sets powered by a large constellation of nanosatellites, such as the tracking of maritime, aviation and weather patterns.

BLFS vs SPIR — Head-to-Head

Bigger by revenue
BLFS
BLFS
1.2× larger
BLFS
$18.8M
$15.8M
SPIR
Growing faster (revenue YoY)
BLFS
BLFS
+51.3% gap
BLFS
24.3%
-26.9%
SPIR
Higher net margin
BLFS
BLFS
235.6% more per $
BLFS
58.9%
-176.6%
SPIR
Faster 2-yr revenue CAGR
BLFS
BLFS
Annualised
BLFS
1.0%
-32.6%
SPIR

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
BLFS
BLFS
SPIR
SPIR
Revenue
$18.8M
$15.8M
Net Profit
$11.1M
$-28.0M
Gross Margin
40.2%
Operating Margin
7.2%
-164.1%
Net Margin
58.9%
-176.6%
Revenue YoY
24.3%
-26.9%
Net Profit YoY
-11.1%
42.7%
EPS (diluted)
$0.23
$-0.85

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
BLFS
BLFS
SPIR
SPIR
Q4 25
$18.8M
$15.8M
Q3 25
$28.1M
$12.7M
Q2 25
$25.4M
$19.2M
Q1 25
$23.9M
$23.9M
Q4 24
$15.1M
$21.7M
Q3 24
$21.4M
$28.6M
Q2 24
$19.7M
$25.4M
Q1 24
$18.4M
$34.8M
Net Profit
BLFS
BLFS
SPIR
SPIR
Q4 25
$11.1M
$-28.0M
Q3 25
$621.0K
$-19.7M
Q2 25
$-15.8M
$119.6M
Q1 25
$-448.0K
$-20.7M
Q4 24
$12.5M
$-48.8M
Q3 24
$-1.7M
$-12.5M
Q2 24
$-20.7M
$-16.6M
Q1 24
$-10.2M
$-25.5M
Gross Margin
BLFS
BLFS
SPIR
SPIR
Q4 25
40.2%
Q3 25
36.6%
Q2 25
48.9%
Q1 25
36.8%
Q4 24
32.4%
Q3 24
44.5%
Q2 24
43.0%
Q1 24
26.5%
Operating Margin
BLFS
BLFS
SPIR
SPIR
Q4 25
7.2%
-164.1%
Q3 25
-0.3%
-166.1%
Q2 25
-65.5%
-122.7%
Q1 25
-5.1%
-106.5%
Q4 24
3.6%
-144.1%
Q3 24
-2.0%
-48.0%
Q2 24
-6.6%
-48.6%
Q1 24
-17.9%
-34.4%
Net Margin
BLFS
BLFS
SPIR
SPIR
Q4 25
58.9%
-176.6%
Q3 25
2.2%
-155.3%
Q2 25
-62.3%
623.4%
Q1 25
-1.9%
-86.5%
Q4 24
82.5%
-225.2%
Q3 24
-8.0%
-43.7%
Q2 24
-105.1%
-65.2%
Q1 24
-55.4%
-73.3%
EPS (diluted)
BLFS
BLFS
SPIR
SPIR
Q4 25
$0.23
$-0.85
Q3 25
$0.01
$-0.61
Q2 25
$-0.33
$3.72
Q1 25
$-0.01
$-0.77
Q4 24
$0.27
$-1.93
Q3 24
$-0.04
$-0.50
Q2 24
$-0.45
$-0.68
Q1 24
$-0.22
$-1.17

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
BLFS
BLFS
SPIR
SPIR
Cash + ST InvestmentsLiquidity on hand
$33.0M
$81.8M
Total DebtLower is stronger
$5.0M
Stockholders' EquityBook value
$371.9M
$112.9M
Total Assets
$405.9M
$211.0M
Debt / EquityLower = less leverage
0.01×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
BLFS
BLFS
SPIR
SPIR
Q4 25
$33.0M
$81.8M
Q3 25
$29.5M
$96.8M
Q2 25
$31.9M
$117.6M
Q1 25
$66.9M
$35.9M
Q4 24
$91.5M
$19.2M
Q3 24
$24.0M
$36.6M
Q2 24
$22.0M
$45.8M
Q1 24
$29.7M
$63.7M
Total Debt
BLFS
BLFS
SPIR
SPIR
Q4 25
$5.0M
Q3 25
$7.5M
Q2 25
$10.1M
Q1 25
$12.9M
$103.7M
Q4 24
$15.9M
$103.1M
Q3 24
$20.1M
$4.9M
Q2 24
$21.1M
$4.9M
Q1 24
$24.3M
$123.1M
Stockholders' Equity
BLFS
BLFS
SPIR
SPIR
Q4 25
$371.9M
$112.9M
Q3 25
$353.7M
$133.1M
Q2 25
$347.2M
$149.2M
Q1 25
$352.6M
$3.7M
Q4 24
$348.9M
$-11.7M
Q3 24
$325.5M
$30.8M
Q2 24
$321.4M
$40.3M
Q1 24
$333.4M
$52.5M
Total Assets
BLFS
BLFS
SPIR
SPIR
Q4 25
$405.9M
$211.0M
Q3 25
$392.1M
$224.3M
Q2 25
$387.2M
$239.5M
Q1 25
$395.1M
$208.8M
Q4 24
$399.5M
$193.6M
Q3 24
$381.7M
$224.2M
Q2 24
$375.0M
$230.8M
Q1 24
$401.6M
$252.3M
Debt / Equity
BLFS
BLFS
SPIR
SPIR
Q4 25
0.01×
Q3 25
0.02×
Q2 25
0.03×
Q1 25
0.04×
27.92×
Q4 24
0.05×
Q3 24
0.06×
0.16×
Q2 24
0.07×
0.12×
Q1 24
0.07×
2.35×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
BLFS
BLFS
SPIR
SPIR
Operating Cash FlowLast quarter
$4.9M
$-4.3M
Free Cash FlowOCF − Capex
$-16.2M
FCF MarginFCF / Revenue
-102.1%
Capex IntensityCapex / Revenue
75.1%
Cash ConversionOCF / Net Profit
0.44×
TTM Free Cash FlowTrailing 4 quarters
$-92.6M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
BLFS
BLFS
SPIR
SPIR
Q4 25
$4.9M
$-4.3M
Q3 25
$6.1M
$-12.0M
Q2 25
$7.4M
$-35.1M
Q1 25
$1.7M
$-8.4M
Q4 24
$1.6M
$-19.2M
Q3 24
$4.8M
$14.0M
Q2 24
$6.5M
$-4.4M
Q1 24
$-4.5M
$-8.8M
Free Cash Flow
BLFS
BLFS
SPIR
SPIR
Q4 25
$-16.2M
Q3 25
$-20.4M
Q2 25
$-38.7M
Q1 25
$-17.3M
Q4 24
$-24.3M
Q3 24
$5.1M
Q2 24
$-9.9M
Q1 24
$-15.9M
FCF Margin
BLFS
BLFS
SPIR
SPIR
Q4 25
-102.1%
Q3 25
-161.3%
Q2 25
-201.7%
Q1 25
-72.6%
Q4 24
-112.2%
Q3 24
17.8%
Q2 24
-39.0%
Q1 24
-45.7%
Capex Intensity
BLFS
BLFS
SPIR
SPIR
Q4 25
75.1%
Q3 25
66.2%
Q2 25
18.8%
Q1 25
37.3%
Q4 24
23.5%
Q3 24
31.2%
Q2 24
21.8%
Q1 24
20.3%
Cash Conversion
BLFS
BLFS
SPIR
SPIR
Q4 25
0.44×
Q3 25
9.83×
Q2 25
-0.29×
Q1 25
Q4 24
0.13×
Q3 24
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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