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Side-by-side financial comparison of Bionano Genomics, Inc. (BNGO) and ILLUMINA, INC. (ILMN). Click either name above to swap in a different company.

ILLUMINA, INC. is the larger business by last-quarter revenue ($1.1B vs $8.0M, roughly 138.9× Bionano Genomics, Inc.). ILLUMINA, INC. runs the higher net margin — 16.8% vs -99.8%, a 116.6% gap on every dollar of revenue. On growth, ILLUMINA, INC. posted the faster year-over-year revenue change (-1.6% vs -2.6%). Over the past eight quarters, ILLUMINA, INC.'s revenue compounded faster (0.8% CAGR vs -4.8%).

Bionano Genomics develops and commercializes proprietary optical genome mapping technology and diagnostic solutions. Its products detect large structural genomic variants with high precision, serving global research institutions, biopharma firms, and clinical labs for oncology, rare disease, and reproductive health use cases.

Illumina, Inc. is an American biotechnology company, headquartered in San Diego, California. Incorporated on April 1, 1998, Illumina develops, manufactures, and markets integrated systems for the analysis of genetic variation and biological function. The company provides a line of products and services that serves the sequencing, genotyping and gene expression, and proteomics markets, and serves more than 155 countries.

BNGO vs ILMN — Head-to-Head

Bigger by revenue
ILMN
ILMN
138.9× larger
ILMN
$1.1B
$8.0M
BNGO
Growing faster (revenue YoY)
ILMN
ILMN
+1.0% gap
ILMN
-1.6%
-2.6%
BNGO
Higher net margin
ILMN
ILMN
116.6% more per $
ILMN
16.8%
-99.8%
BNGO
Faster 2-yr revenue CAGR
ILMN
ILMN
Annualised
ILMN
0.8%
-4.8%
BNGO

Income Statement — Q4 2025 vs Q4 2025

Metric
BNGO
BNGO
ILMN
ILMN
Revenue
$8.0M
$1.1B
Net Profit
$-7.9M
$186.0M
Gross Margin
42.8%
65.9%
Operating Margin
-107.4%
15.8%
Net Margin
-99.8%
16.8%
Revenue YoY
-2.6%
-1.6%
Net Profit YoY
60.6%
205.7%
EPS (diluted)
$-0.12
$1.16

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
BNGO
BNGO
ILMN
ILMN
Q4 25
$8.0M
Q3 25
$7.4M
Q2 25
$6.7M
Q1 25
$6.5M
Q4 24
$8.2M
$1.1B
Q3 24
$6.1M
$1.1B
Q2 24
$7.8M
$1.1B
Q1 24
$8.8M
$1.1B
Net Profit
BNGO
BNGO
ILMN
ILMN
Q4 25
$-7.9M
Q3 25
$-8.5M
Q2 25
$-6.9M
Q1 25
$-3.1M
Q4 24
$-20.1M
$186.0M
Q3 24
$-44.2M
$705.0M
Q2 24
$-16.2M
$-2.0B
Q1 24
$-31.4M
$-126.0M
Gross Margin
BNGO
BNGO
ILMN
ILMN
Q4 25
42.8%
Q3 25
45.7%
Q2 25
51.6%
Q1 25
45.5%
Q4 24
41.9%
65.9%
Q3 24
-139.1%
69.0%
Q2 24
33.3%
64.8%
Q1 24
32.2%
62.0%
Operating Margin
BNGO
BNGO
ILMN
ILMN
Q4 25
-107.4%
Q3 25
-115.9%
Q2 25
-115.8%
Q1 25
-131.1%
Q4 24
-146.3%
15.8%
Q3 24
-722.9%
68.6%
Q2 24
-219.0%
-147.2%
Q1 24
-354.9%
-10.3%
Net Margin
BNGO
BNGO
ILMN
ILMN
Q4 25
-99.8%
Q3 25
-115.4%
Q2 25
-101.8%
Q1 25
-48.0%
Q4 24
-246.5%
16.8%
Q3 24
-728.6%
65.3%
Q2 24
-208.8%
-178.8%
Q1 24
-358.3%
-11.7%
EPS (diluted)
BNGO
BNGO
ILMN
ILMN
Q4 25
$-0.12
Q3 25
$-1.59
Q2 25
$-1.99
Q1 25
$-1.15
Q4 24
$-7.05
$1.16
Q3 24
$-30.92
$4.42
Q2 24
$-14.41
$-12.48
Q1 24
$-35.75
$-0.79

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
BNGO
BNGO
ILMN
ILMN
Cash + ST InvestmentsLiquidity on hand
$3.0M
$93.0M
Total DebtLower is stronger
Stockholders' EquityBook value
$44.4M
$2.4B
Total Assets
$73.6M
$6.3B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
BNGO
BNGO
ILMN
ILMN
Q4 25
$3.0M
Q3 25
$3.1M
Q2 25
$3.6M
Q1 25
$3.6M
Q4 24
$9.2M
$93.0M
Q3 24
$8.8M
$70.0M
Q2 24
$10.4M
$74.0M
Q1 24
$15.8M
Stockholders' Equity
BNGO
BNGO
ILMN
ILMN
Q4 25
$44.4M
Q3 25
$49.8M
Q2 25
$45.4M
Q1 25
$48.2M
Q4 24
$35.4M
$2.4B
Q3 24
$48.9M
$2.1B
Q2 24
$80.3M
$1.4B
Q1 24
$82.8M
$5.7B
Total Assets
BNGO
BNGO
ILMN
ILMN
Q4 25
$73.6M
Q3 25
$79.1M
Q2 25
$76.0M
Q1 25
$78.4M
Q4 24
$76.7M
$6.3B
Q3 24
$87.4M
$6.0B
Q2 24
$129.4M
$6.1B
Q1 24
$158.0M
$10.0B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
BNGO
BNGO
ILMN
ILMN
Operating Cash FlowLast quarter
$-4.2M
$364.0M
Free Cash FlowOCF − Capex
$335.0M
FCF MarginFCF / Revenue
30.3%
Capex IntensityCapex / Revenue
2.6%
Cash ConversionOCF / Net Profit
1.96×
TTM Free Cash FlowTrailing 4 quarters
$709.0M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
BNGO
BNGO
ILMN
ILMN
Q4 25
$-4.2M
Q3 25
$-5.9M
Q2 25
$-3.5M
Q1 25
$-2.8M
Q4 24
$-6.5M
$364.0M
Q3 24
$-13.3M
$316.0M
Q2 24
$-21.0M
$80.0M
Q1 24
$-28.1M
$77.0M
Free Cash Flow
BNGO
BNGO
ILMN
ILMN
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
$335.0M
Q3 24
$284.0M
Q2 24
$49.0M
Q1 24
$41.0M
FCF Margin
BNGO
BNGO
ILMN
ILMN
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
30.3%
Q3 24
26.3%
Q2 24
4.4%
Q1 24
3.8%
Capex Intensity
BNGO
BNGO
ILMN
ILMN
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
2.6%
Q3 24
3.0%
Q2 24
2.8%
Q1 24
3.3%
Cash Conversion
BNGO
BNGO
ILMN
ILMN
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
1.96×
Q3 24
0.45×
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

BNGO
BNGO

Segment breakdown not available.

ILMN
ILMN

Sequencing$1.0B91%
Microarray$101.0M9%
Investee$7.0M1%

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