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Side-by-side financial comparison of BioNTech SE (BNTX) and ILLUMINA, INC. (ILMN). Click either name above to swap in a different company.

BioNTech SE is the larger business by last-quarter revenue ($1.5B vs $1.2B, roughly 1.3× ILLUMINA, INC.). ILLUMINA, INC. runs the higher net margin — 28.8% vs -1.9%, a 30.7% gap on every dollar of revenue.

BioNTech SE is a German multinational biotechnology company headquartered in Mainz that develops immunotherapies and vaccines, particularly for cancer and infectious diseases.

Illumina, Inc. is an American biotechnology company, headquartered in San Diego, California. Incorporated on April 1, 1998, Illumina develops, manufactures, and markets integrated systems for the analysis of genetic variation and biological function. The company provides a line of products and services that serves the sequencing, genotyping and gene expression, and proteomics markets, and serves more than 155 countries.

BNTX vs ILMN — Head-to-Head

Bigger by revenue
BNTX
BNTX
1.3× larger
BNTX
$1.5B
$1.2B
ILMN
Higher net margin
ILMN
ILMN
30.7% more per $
ILMN
28.8%
-1.9%
BNTX

Income Statement — Q3 FY2025 vs Q4 FY2025

Metric
BNTX
BNTX
ILMN
ILMN
Revenue
$1.5B
$1.2B
Net Profit
$-28.7M
$334.0M
Gross Margin
65.5%
Operating Margin
-3.1%
17.4%
Net Margin
-1.9%
28.8%
Revenue YoY
5.0%
Net Profit YoY
185.5%
EPS (diluted)
$2.16

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
BNTX
BNTX
ILMN
ILMN
Q4 25
$1.2B
Q3 25
$1.5B
Q2 25
$260.8M
Q4 24
$1.1B
Q3 24
$1.2B
$1.1B
Q2 24
$1.1B
Q1 24
$1.1B
Q4 23
$1.1B
Net Profit
BNTX
BNTX
ILMN
ILMN
Q4 25
$334.0M
Q3 25
$-28.7M
Q2 25
$-386.6M
Q4 24
$186.0M
Q3 24
$198.1M
$705.0M
Q2 24
$-2.0B
Q1 24
$-126.0M
Q4 23
$-754.0M
Gross Margin
BNTX
BNTX
ILMN
ILMN
Q4 25
65.5%
Q3 25
Q2 25
Q4 24
65.9%
Q3 24
69.0%
Q2 24
64.8%
Q1 24
62.0%
Q4 23
61.1%
Operating Margin
BNTX
BNTX
ILMN
ILMN
Q4 25
17.4%
Q3 25
-3.1%
Q2 25
-192.1%
Q4 24
15.8%
Q3 24
0.8%
68.6%
Q2 24
-147.2%
Q1 24
-10.3%
Q4 23
-67.4%
Net Margin
BNTX
BNTX
ILMN
ILMN
Q4 25
28.8%
Q3 25
-1.9%
Q2 25
-148.2%
Q4 24
16.8%
Q3 24
15.9%
65.3%
Q2 24
-178.8%
Q1 24
-11.7%
Q4 23
-67.4%
EPS (diluted)
BNTX
BNTX
ILMN
ILMN
Q4 25
$2.16
Q3 25
Q2 25
Q4 24
$1.16
Q3 24
$4.42
Q2 24
$-12.48
Q1 24
$-0.79
Q4 23
$-4.77

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
BNTX
BNTX
ILMN
ILMN
Cash + ST InvestmentsLiquidity on hand
$1.6B
Total DebtLower is stronger
Stockholders' EquityBook value
$2.7B
Total Assets
$6.6B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
BNTX
BNTX
ILMN
ILMN
Q4 25
$1.6B
Q3 25
Q2 25
Q4 24
$93.0M
Q3 24
$70.0M
Q2 24
$74.0M
Q1 24
Q4 23
$6.0M
Stockholders' Equity
BNTX
BNTX
ILMN
ILMN
Q4 25
$2.7B
Q3 25
Q2 25
Q4 24
$2.4B
Q3 24
$2.1B
Q2 24
$1.4B
Q1 24
$5.7B
Q4 23
$5.9B
Total Assets
BNTX
BNTX
ILMN
ILMN
Q4 25
$6.6B
Q3 25
Q2 25
Q4 24
$6.3B
Q3 24
$6.0B
Q2 24
$6.1B
Q1 24
$10.0B
Q4 23
$10.1B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
BNTX
BNTX
ILMN
ILMN
Operating Cash FlowLast quarter
$321.0M
Free Cash FlowOCF − Capex
$267.0M
FCF MarginFCF / Revenue
23.0%
Capex IntensityCapex / Revenue
Cash ConversionOCF / Net Profit
0.96×
TTM Free Cash FlowTrailing 4 quarters
$935.0M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
BNTX
BNTX
ILMN
ILMN
Q4 25
$321.0M
Q3 25
Q2 25
Q4 24
$364.0M
Q3 24
$316.0M
Q2 24
$80.0M
Q1 24
$77.0M
Q4 23
$139.0M
Free Cash Flow
BNTX
BNTX
ILMN
ILMN
Q4 25
$267.0M
Q3 25
Q2 25
Q4 24
$335.0M
Q3 24
$284.0M
Q2 24
$49.0M
Q1 24
$41.0M
Q4 23
$94.0M
FCF Margin
BNTX
BNTX
ILMN
ILMN
Q4 25
23.0%
Q3 25
Q2 25
Q4 24
30.3%
Q3 24
26.3%
Q2 24
4.4%
Q1 24
3.8%
Q4 23
8.4%
Capex Intensity
BNTX
BNTX
ILMN
ILMN
Q4 25
Q3 25
Q2 25
Q4 24
2.6%
Q3 24
3.0%
Q2 24
2.8%
Q1 24
3.3%
Q4 23
4.0%
Cash Conversion
BNTX
BNTX
ILMN
ILMN
Q4 25
0.96×
Q3 25
Q2 25
Q4 24
1.96×
Q3 24
0.45×
Q2 24
Q1 24
Q4 23

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

BNTX
BNTX

Segment breakdown not available.

ILMN
ILMN

Product revenue$990.0M85%
Service and other revenue$169.0M15%

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